Pulmonary rehabilitation to decrease perioperative risks of spinal fusion for patients with neuromuscular scoliosis and low vital capacity.

BACKGROUND: In patients with neuromuscular disease and a forced vital capacity (FVC) of <30% of the predictive value, scoliosis correction operation was not recommended because of the possibility of subsequent complications. However, recent reports suggest that the operation can be performed safelyeven in these patients. AIM: This study aimed to determine the usefulness of pulmonary rehabilitation for scoliosis operation, in cases of patients with a low FVC. DESIGN: A retrospective study of a clinical case series SETTING: Inpatients of a university hospital POPULATION: Neuromuscular patients with a low FVC who received mechanical correction of scoliosis (N.=24). METHODS: End-tidal or transcutaneous carbon dioxide was monitored and noninvasive intermittent positive pressure ventilation was applied as needed to maintain normal carbon dioxide concentration. Air stacking, manually assisted coughing and mechanical insufflation-exsufflation were used to maintain normal oxygen saturation. RESULTS: A total of 24 patients of neuromuscular disease (mean age: 15.2 years; average FVC: 19.2%) were included Noninvasive intermittent positive pressure ventilator (NIPPV) was applied in 22 of the 24 patients. The endotracheal tubes of all except two patients were removed within 3 days after the operation, and they were transferred to the general ward within 3 days of extubation. Eight patients had complications, such as pneumonia, wound infection, heart failure, and debility, which were controlled easily with medical management, there were neither life-threatening complications nor a need for an invasiverespiratory intervention. CONCLUSION: Through pulmonary rehabilitation, scoliosis correction surgery could be performed safely even in patients with a neuromuscular disease and a low FVC. CLINICAL REHABILITATION IMPACT: The findings of this study can be used as a basis for practical guidelines for successful and safe mechanical correction of neuromuscular scoliosis.

Permanent Genetic Resources added to Molecular Ecology Resources Database 1 June 2010 - 31 July 2010.

This article documents the addition of 205 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Bagassa guianensis, Bulweria bulwerii, Camelus bactrianus, Chaenogobius annularis, Creontiades dilutus, Diachasmimorpha tryoni, Dioscorea alata, Euhrychiopsis lecontei, Gmelina arborea, Haliotis discus hannai, Hirtella physophora, Melanaphis sacchari, Munida isos, Thaumastocoris peregrinus and Tuberolachnus salignus. These loci were cross-tested on the following species: Halobaena caerulea, Procellaria aequinoctialis, Oceanodroma monteiroi, Camelus ferus, Creontiades pacificus, Dioscorea rotundata, Dioscorea praehensilis, Dioscorea abyssinica, Dioscorea nummularia, Dioscorea transversa, Dioscorea esculenta, Dioscorea pentaphylla, Dioscorea trifida, Hirtella bicornis, Hirtella glandulosa, Licania alba, Licania canescens, Licania membranaceae, Couepia guianensis and 7 undescribed Thaumastocoris species.