Analyzing evidence-based falls prevention data with significant missing information using variable selection after multiple imputation.

Falls are the leading cause of fatal and non-fatal injuries among older adults. Evidence-based fall prevention programs are delivered nationwide, largely supported by funding from the Administration for Community Living (ACL), to mitigate fall-related risk. This study utilizes data from 39 ACL grantees in 22 states from 2014 to 2017. The large amount of missing values for falls efficacy in this national database may lead to potentially biased statistical results and make it challenging to implement reliable variable selection. Multiple imputation is used to deal with missing values. To obtain a consistent result of variable selection in multiply-imputed datasets, multiple imputation-stepwise regression (MI-stepwise) and multiple imputation-least absolute shrinkage and selection operator (MI-LASSO) methods are used. To compare the performances of MI-stepwise and MI-LASSO, simulation studies were conducted. In particular, we extended prior work by considering several circumstances not covered in previous studies, including an extensive investigation of data with different signal-to-noise ratios and various missing data patterns across predictors, as well as a data structure that allowed the missingness mechanism to be missing not at random (MNAR). In addition, we evaluated the performance of MI-LASSO method with varying tuning parameters to address the overselection issue in cross-validation (CV)-based LASSO.

Six Minutes of Physical Activity Improves Mood in Older Adults: A Pilot Study.

BACKGROUND AND PURPOSE: The purposes of this study were to examine (1) differences in mood and motivation among older adults after the completion of 6 minutes of self-paced walking (6MW) and (2) the relationship between pace and magnitude of mood change. METHODS: Eleven participants completed 3 days of testing where energy, fatigue, tension, depression, confusion, mental and physical energy, and motivation to perform mental tasks were measured before and after the 6MW. A repeated-measures analysis of variance was used to examine changes in mood and motivation, and a bivariate Pearson correlation was used to determine relationships between pace and magnitude of changes in mood. RESULTS: Faster pace was associated with significant improvements (P < .05) in fatigue, energy, tension, confusion, total mood disturbance, state mental fatigue, and state physical energy. A significant relationship was noted between pace and changes in energy, fatigue, state mental and physical energy, and fatigue in the expected direction. DISCUSSION: Results indicate that mood is influenced by pace of the activity. Findings suggest that even 6 minutes of physical activity can improve moods, which may impact how physical therapists approach prescribing exercise to older adults.

Examining the Role of Weight Status and Individual Attributes on Adolescent Social Relations.

PURPOSE: Weight stigmatization during adolescence may compromise the development of social relations important for the development. This study examined the associations between weight status and likelihood of nomination (indegree) for five different social network types-friendship, romantic, admiration, succeed, and popularity. METHODS: Data for the study were from 1,110 tenth grade students (aged 11-19 years) from four high schools in one Los Angeles school district in 2010. Multiple Poisson regression analyses using generalized linear model were conducted to examine the relationship between weight status (underweight/normal weight/overweight measured with body mass index calculated from self-reported height and weight) and adolescents' indegree for the five different networks. RESULTS: Obese adolescents were significantly less likely to be nominated as romantic interest (odds ratio [OR]: .29, 95% confidence interval [CI]: .19-42), admired (OR: .80, 95% CI: .65-.97), or popular (OR: .71, 95% CI: .57-.88) compared with their normal weight peers. Overweight adolescents were also less likely to be nominated as a romantic interest (OR: .57, 95% CI: .42-.78) or popular (OR: .67, 95% CI: .53-.84) compared with those who were normal weight. Underweight adolescents were also less likely to be nominated as friends (OR: .76, 95% CI: .60-98), someone admired (OR: .61, 95% CI: .42-.89), likely to succeed (OR: .62, 95% CI: .44-.87), or popular (OR: .40, 95% CI: .25-.64). CONCLUSIONS: Our results suggest weight status is associated with being selected by peers into different types of adolescent networks. Underweight, overweight, and obese adolescents are at an increased risk for social isolation because of their weight. This may have a negative impact on their peer relations important for social development, self-esteem, and mental health.

Impact of Diabetes Self-Management Education on Psychological Distress and Health Outcomes Among African Americans and Hispanics/Latinos With Diabetes.

PURPOSE: Diabetes self-management education and support (DSME/S) is an effective strategy to improve health outcomes. However, little is known about the impact of formal DSME/S on psychological distress among minority populations. The study purposes were to 1) explore the impact of a culturally tailored DSME/S intervention on psychological distress and diabetes-related outcomes among African-American and Hispanic/Latino participants and 2) examine differences across groups in self-care, self-efficacy, diabetes knowledge, and psychological distress. METHODS: Using a pre- and post-test research design, baseline and post-test assessments were conducted at weeks 1 and 7 of the intervention, respectively. Statistical analyses included descriptive statistics for demographic variables and four outcomes (self-care, self-efficacy, knowledge, and psychological distress score), general linear regression analysis of the post-test outcomes, and the Spearman correlation between psychological distress score and the outcomes. RESULTS: Compared to African-American participants (n = 122), Hispanic/Latino participants (n = 137) were significantly younger and less educated. The two groups were comparable in sex, income, and health status. Significant pre- to post-test improvements were seen in each group for self-care, self-efficacy, and psychological distress. Diabetes knowledge had moderate improvement. Hispanics/Latinos had significantly greater post-test self-efficacy and self-care scores compared to African Americans. For both African-American and Hispanic/Latino participants, lower psychological distress scores were generally associated with greater self-efficacy and self-care. Psychological distress scores were not significantly associated with knowledge in African-Amerian or Hispanic/Latino participants. For African Americans only, better health status was significantly associated with less psychological distress. CONCLUSION: DSME/S programs have the potential to improve psychological health among African Americans and Hispanics/Latinos, which can lead to better diabetes outcomes.

Participation of lower-to-middle wage workers in a study of Chronic Disease Self-Management Program (CDSMP) effectiveness: Implications for reducing chronic disease burden among racial and ethnic minority populations.

BACKGROUND: Although the Chronic Disease Self-Management Program (CDSMP) improves chronic disease outcomes, little is known about CDSMP participation in populations less than 65 years of age. We explore study and CDSMP participation rates by demographic characteristics with younger (40-64 years old), lower-to-middle wage workers with chronic disease in a randomized clinical trial (RCT) conducted in North Carolina. METHODS: Descriptive statistics and regression models were used to examine associations between demographic, chronic disease burden, and employment variables, and time-dependent study enrollment and intervention participation outcomes that ranged from initiating consent (n = 1,067) to CDSMP completion (n = 41). RESULTS: Overall, participation among non-Whites was disproportionately higher (43%-59%) than that of Whites (42%-57%) relative to the age-matched racial composition of North Carolina (31% non-White and 69% White). Among participants randomized to the CDSMP, racial and ethnic minorities had the highest rates of participation. There were no significant demographic, chronic disease burden, or employment predictors among the participation outcomes examined, although this may have been due to the limited number of CDSMP workshop participation observations. CONCLUSIONS: Extending the CDSMP to lower-to-middle wage workers may be particularly effective in reaching racial and ethnic minority populations, who complete the program to a greater extent than their White, non-Hispanic counterparts.

Associations for tasks requiring single stimulus and working memory with different aspects of gait and posture: an exploratory study.

Evidence suggests that there is a significant relationship between cognition and gait. However, studies have primarily focused on overall cognition when elucidating the relationship with gait. This study aimed to delineate specific aspects of cognition that are related to gait and postural control parameters. Participants (N = 11, age = 76.55 ± 7.58 years) performed a series of cognitive tasks categorized as either lower-level (serial subtract 3 and continuous performance task) or higher-level (serial subtract 7 and rapid visual input processing task) tasks. Following the completion of the cognitive tasks, participants performed balance and gait activities. This procedure was performed on two separate days with a minimum 48-h rest period between days. A bivariate Pearson correlation analysis was utilized to identify relationships between cognitive task scores and gait speed, step length, gait imbalance as well as the visual, vestibular, and somatosensory aspect of postural control. Lower-level cognitive tasks, specifically the serial subtract 3 was significantly (P < 0.05) associated with gait speed (r = 0.457), step length (r = 0.481), and the ability to maintain postural control with occluded vision and unreliable somatosensory input (r = -0.504). In contrast, higher-level cognitive tasks, specifically serial subtract 7 were associated (P < 0.05) with gait imbalance (r = -0.540), while rapid visual input processing primary reaction time was associated with the ability to maintain postural control in the absence of visual input (r = -0.751). Our findings align with functional magnetic resonance imaging (fMRI) studies that examine gait, postural control, and cognitive task performance and provide a granular insight. These results may help us to better understand the relationship between cognitive deficits, gait, and postural control with aging.

The science of sustaining health behavior change: the health maintenance consortium.

OBJECTIVE: To enhance understanding of the long-term maintenance of behavior change, as well as effective strategies for achieving sustainable health promotion and disease prevention through the Health Maintenance Consortium (HMC). METHODS: This introductory research synthesis prepared by the resource center gives context to this theme issue by providing an overview of the HMC and the articles in this journal. RESULTS: It explores the contributions to our conceptualization of behavior change processes and intervention strategies, the trajectory of effectiveness of behavioral and social interventions, and factors influencing the long-term maintenance of behavioral and social interventions. CONCLUSIONS: Future directions for furthering the science of maintaining behavior change and reducing the gaps between research and practice are recommended.