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1.
Regul Toxicol Pharmacol ; 63(1): 171-6, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22406137

RESUMO

We measured consumer exposure to formaldehyde (FA) from personal care products (PCP) containing FA-releasing preservatives. Six study subjects applied facial moisturiser, foundation, shower gel, shampoo, deodorant, hair conditioner, hair styling gel or body lotion at the 90th percentile amount of EU PCP consumer use. FA air concentrations were measured in the empty room, in the presence of study subjects prior to PCP use, and for one hour (breathing zone, area monitoring) after PCP use. The mean FA air concentration in the empty bathroom was 1.32 ± 0.67 µg/m³, in the presence of subjects it was 2.33 ± 0.86 µg/m³). Except for body lotion and hair conditioner (6.2 ± 0.1.9 or 4.5 ± 0.1.5 µg/m³, respectively), mean 1-h FA air concentrations after PCP use were similar to background. Peak FA air concentrations, ranging from baseline values (2.2 µg/m³; shower gel) to 11.5 µg/m³ (body lotion), occurred during 0-5 to 5-10 min after PCP use. Despite of exaggerated exposure conditions, FA air levels were a fraction of those considered to be safe (120 µg/m³), occurring in indoor air (22-124 µg/m³) or expired human breath (1.4-87 µg/m³). Overall, our data yielded evidence that inhalation of FA from the use of PCP containing FA-releasers poses no risk to human health.


Assuntos
Poluentes Atmosféricos/análise , Poluição do Ar em Ambientes Fechados/análise , Cosméticos/análise , Formaldeído/análise , Exposição por Inalação/análise , Adulto , Qualidade de Produtos para o Consumidor , Monitoramento Ambiental , Feminino , Humanos , Medição de Risco , Adulto Jovem
2.
Skin Res Technol ; 13(1): 101-9, 2007 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-17250540

RESUMO

BACKGROUND: Age-induced skin color variations are of great importance and incite increasing demand for cosmetic products to improve the appearance. The evaluation by clinicians or estheticians of the efficacy of skin care products is particularly difficult and requires the help of color charts. PURPOSE: To standardize this kind of evaluation, we have developed a new Skin Color Chart. In contrast to other color charts, this new one represents true skin color without metamerism and covers almost all skin colors encountered around the world. This new instrument has been validated for both Asian and Caucasian skin complexion and sun spot color. METHOD: The new device used to record skin color, the Chromasphere, developed by L'Oréal, is briefly presented. All skin color measurements and the validation of each selected Color were performed under identical conditions, and then, absorption spectra of both skin and chart were compared using severe criteria. The first use and the validation of this Skin Color Chart were performed by dermatologists (two in China and one in France) in groups of about 40 women on sunspots and complexion color. RESULTS: Regarding repeatability (intraobserver agreement), the new Skin Color Chart showed very good statistical validation on complexion and sunspot color. The agreement between dermatologists, the reproducibility criterion, although not as good remained high. An example of the evaluation of the efficacy of a whitening product is given in order to illustrate the 'sensitivity' of this new device to evaluate very weak color variations. CONCLUSIONS: The new Skin Color Chart appears to be very useful and easy to use even by clinicians without training in color evaluation.


Assuntos
Cor/normas , Colorimetria/instrumentação , Colorimetria/normas , Dermoscopia/instrumentação , Dermoscopia/normas , Guias de Prática Clínica como Assunto , Pigmentação da Pele , Colorimetria/métodos , Dermoscopia/métodos , Desenho de Equipamento , Análise de Falha de Equipamento , França , Humanos , Valores de Referência , Reprodutibilidade dos Testes , Sensibilidade e Especificidade
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