RESUMO
The efficacy of intraruminal albendazole (ABZ) capsules (Profitril-Captec) and the effect of treatment on productivity were studied in 300 ewes infected with gastrointestinal nematodes and the trematode Dicrocoelium dendriticum. Coprological tests revealed that treated animals remained negative for 10 weeks after the administration of capsules. Contamination of pasture with nematode larvae was significantly reduced during the whole experiment. Necropsy of 14 animals (seven treated and seven untreated) showed 96.9-99.2% efficacy against the nematodes Nematodirus spp., Oesophagostomum spp., Cooperia spp., Trichostrongylus spp. and Trichuris ovis, while efficacy was 88.5% against D. dendriticum. During the 6 month pasture season (May-October 1989), treated ewes produced on average 2.56 kg cheese and 0.6 kg wool per ewe more than untreated controls. Our study confirms the reliability of the ABZ slow-release capsules over 90 days and the positive effect of treatment on nematode contamination of pasture and ewe productivity.
Assuntos
Albendazol/administração & dosagem , Nematoides/efeitos dos fármacos , Infecções por Nematoides/veterinária , Doenças dos Ovinos/parasitologia , Albendazol/uso terapêutico , Animais , Cápsulas , Queijo , Preparações de Ação Retardada , Fezes/parasitologia , Feminino , Infecções por Nematoides/tratamento farmacológico , Infecções por Nematoides/parasitologia , Esofagostomíase/tratamento farmacológico , Esofagostomíase/parasitologia , Esofagostomíase/veterinária , Oesophagostomum/efeitos dos fármacos , Contagem de Ovos de Parasitas/veterinária , Ovinos , Doenças dos Ovinos/tratamento farmacológico , Tricostrongilose/tratamento farmacológico , Tricostrongilose/parasitologia , Tricostrongilose/veterinária , Trichostrongylus/efeitos dos fármacos , Tricuríase/tratamento farmacológico , Tricuríase/parasitologia , Tricuríase/veterinária , Trichuris/efeitos dos fármacos , LãRESUMO
Tests were performed to examine the effectiveness of a new form of cambendazole (Bonlam paste, produced by MSD, USA) in sheep, naturally invaded by the trematodes Dicrocoelium dendriticum. Single administration of 25 mg per 1 kg live weight induced a rapid decrease in the number of the excreted eggs of D. dendriticum, as counted during ovoscopic examination seven, ten, and fifteen days after administration of the chemical. The intenseffectiveness of the preparation, determined post mortem, was 95.1%. Despite this, several dicrocoelia with normal motility and with no changes on the cuticle or internal organs were found in all the animals dissected. The animals tolerated the treatment with no signs of side-effects.
