1.
J Org Chem
; 88(24): 17227-17236, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38019169
RESUMO
This study presents a convenient approach to the synthesis of indole- and benzofuran-based benzylic sulfones using unactivated alkynes containing aryl iodides and sodium sulfinates under visible light irradiation. The procedure involves a sequential series of dehalogenation, carbo-cyclization, and radical sulfonylation. Plausible insights into the reaction mechanism are derived from control experiments, leading to the proposal of a radical cascade reaction pathway.