Just-in-time Training with Remote Guidance for Ultrasound-Guided Percutaneous Intervention.

BACKGROUND: Management of surgical emergencies in spaceflight will pose a challenge as the era of exploration class missions dawns, requiring increased crew autonomy at a time when training and supplies will be limited. Ultrasound-guided percutaneous intervention would allow for the management of a variety of pathologies with largely shared equipment and training. This proof-of-concept work attempts to determine the feasibility of "just-in-time" remote teaching and guidance of a sample procedure of this type.METHODS: Subjects naïve to ultrasound-guided intervention were instructed via a short video regarding the technique for placement of a percutaneous drain into a simulated abscess within a gel phantom. Subjects were then guided through the performance of the procedure via two-way audiovisual communication with an experienced remote assistant. Technical success was determined by the successful aspiration or expression of fluid from the simulated abscess following drain placement. This was then performed by and compared with staff experienced with such procedures. Time to completion and number of needle redirections required were also measured.RESULTS: All 29 subjects naïve to interventional work and the 4 experienced control subjects achieved technical success. There was a statistically significant difference in the time to completion between the two groups, with the experienced subjects averaging 2 min to completion and the inexperienced 5.8 min. There was no statistically significant difference in the number of redirections.DISCUSSION: This proof-of-concept work demonstrates high rates of technical success of percutaneous ultrasound-guided intervention in previously inexperienced personnel when provided with brief just-in-time training and live two-way audiovisual guidance.Lerner DJ, Pohlen MS, Apland RC, Parivash SN. Just-in-time training with remote guidance for ultrasound-guided percutaneous intervention. Aerosp Med Hum Perform. 2022; 93(12):882-886.

Ultrasound Guided Lumbar Puncture and Remote Guidance for Potential In-Flight Evaluation of VIIP/SANS.

INTRODUCTION: Changes of visual function/neuro-opthalmic structures during spaceflight have been described as visual impairment and intracranial pressure syndrome (VIIP)/spaceflight-associated neuro-ocular syndrome (SANS). Although theories are suggested, the mechanism is unknown. Only indirect measurements of intracranial pressure (ICP) have been performed in spaceflight. Direct determination of in-flight ICP is crucial to understanding VIIP. Current "gold standard" is lumbar puncture (LP). The only direct evaluation has occurred with postflight LP. In-flight measurements would allow correlation of opening pressures/possible contributing factors. The only imaging modality on the International Space Station (ISS) is ultrasound. With appropriate methodology, remotely guided ultrasound-guided lumbar puncture (USGLP) may allow safe performance in flight. Therefore, we sought to develop a novel ultrasound approach for definitive placement of an LP needle, and to show this can be achieved with remote guidance by those without training.METHODS: Literature review and round-table discussions with multiple medical fields was performed. Volunteers were scanned with ultrasound for optimizing technique. A cadaver was used to perform this technique by a radiologist, then taught to volunteers not experienced in image guided procedures, and finally was repeated multiple times by volunteers with simulated remote guidance.RESULTS: Optimal visualization was in the fetal and seated exaggerated kyphotic [corrected] positions. Technical success was achieved by the radiologist in all attempts and achieved in 9 of 11 attempts by the trainees.DISCUSSION: Given ultrasound experience at NASA and the ability to educate non-image-guided trained personnel, these could make this technique feasible and aid in direct in-flight measurements to further research VIIP.Lerner DJ, Chima RS, Patel K, Parmet AJ. Ultrasound guided lumbar puncture and remote guidance for potential in-flight evaluation of VIIP. Aerosp Med Hum Perform. 2019; 90(1):58-62.

Technique for Performing Lumbar Puncture in Microgravity Using Portable Radiography.

INTRODUCTION: Visual Impairment and Intracranial Pressure Syndrome (VIIP) has caused symptomatology during and after long duration missions on the International Space Station (ISS). Only indirect measurements of intracranial pressure (ICP), such as ultrasound, have been performed on ISS. Discussion and interest has happened at NASA about performing lumbar puncture (LP) in microgravity. Only the "blind" palpation approach and the ultrasound-assisted approach have been discussed. This article, as proof of concept, discusses the possibility of portable radiography to assist lumbar punctures in microgravity. METHOD: An anthropomorphic radiological phantom of an adult lumbar spine was made containing a fluid-filled space in the spinal canal with a latex membrane which simulated the dural sac and cerebrospinal fluid. A portable direct-digital radiography system with wireless transmitting image receptor and screen was used to perform image-guided lumbar puncture. Using the same equipment and technique, this procedure was then performed on a cadaver for final proof of concept. RESULTS: Technical success was achieved in all approaches on the first try without needle redirection. There was no difference between the cadaver model and the phantom model in terms of difficulty in reaching the fluid space or visually confirming needle location. DISCUSSION: Portable radiography via proof of concept has the potential to guide lumbar puncture while minimizing volume and mass of equipment. This could be ideal for assisting in performing lumbar puncture in microgravity, as this is the standard of care on Earth for difficult or failed "blind" lumbar punctures. Lerner DJ, Parmet AJ, Don S, Shimony JS, Goyal MS. Technique for performing lumbar puncture in microgravity using portable radiography. Aerosp Med Hum Perform. 2016; 87(8):745-747.

Portable radiography: a reality and necessity for ISS and explorer-class missions.

On ISS missions and explorer class missions, unexpected medical and surgical emergencies could be disastrous. Lack of ability to rapidly assess and make critical decisions affects mission capability. Current imaging modalities on ISS consist only of ultrasound. There are many acute diagnoses which ultrasound alone cannot diagnose. Portable X-Ray imaging (radiography) technology has advanced far enough to where it is now small enough, cheap enough, and accurate enough to give diagnostic quality images sent wirelessly to the onboard computer and on Earth for interpretation while fitting in something the size of a briefcase. Although further research is warranted, Portable Radiography is an important addition to have on ISS and future Explorer Class Missions while maintaining a very small footprint.

Interventional radiology: the future of surgery in microgravity.

Explorer Class missions face situations requiring innovative answers, including medical/surgical dilemmas. Interventional radiology (IR) could play a very important role as sonographically guided procedures make possible many minimally invasive surgical solutions. A review of IR was performed, including performing many IR procedures. Surgical equipment is limited in microgravity. General anesthesia, surgical skill, large mass/volume equipment, and postsurgical/postanesthesia care are among the reasons that open compartment/laparoscopic procedures are undesirable. Sonographically guided percutaneous procedures treat these issues with minimal sedation. Catheters are interchangeable and extremely lightweight and placement could be performed with 0.5 lb (0.2268 kg) of material, nearly a 1000 fold decrease in mass from normal surgical devices. These carry a lower risk of complications comparable to surgery. These can further be researched using the KC-135 and remote "bases." Although further research is required, IR is ideally suited to handle many predicted medical problems that might arise during Explorer Class missions. The percutaneous treatment would allow symptoms to resolve during the mission, and be fully cured upon return to Earth.