[The structural and functional status of the immune system in pre-school children infected with Mycobacterium tuberculosis]. / Strukturno-funktsional'noe sostoianie immunnoi sistemy u detei rannego vozrasta, infitsirovannykh mikobakteriiami tuberkuleza.

Sixty children infected with Mycobacterium tuberculosis (MBT), aged 3 to 5 years were followed up in the period before specific chemotherapy. The studies established structural and functional changed in the immune system in young MBT-infected children. Moreover, the disorders found in immune homeostasis were of combined nature. This circumstance should be taken into account in elaborating immune rehabilitative programs for this group of patients.

[Specific features of functional activity of neutrophilic granulocytes in infection with Mycobacterium tuberculosis in children of different age groups]. / Osobennosti funktsional'noi aktivnosti neitrofil'nykh granulotsitov pri infitsirovanii mikobakteriiami tuberkuleza u detei razlichnykh vozrastnykh grupp.

Sixty children infected with Mycobacteria tuberculosis from two age groups (3-5 and 12-14 years) were followed up. The phagocytic activity and oxygen-dependent biocidicity of peripheral neutrophilic granulocytes were studied. The studies indicated dysfunctions of neutrophilic granulocytes in the children infected with Mycobacteria tuberculosis. This fact should be borne in mind in developing immunorehabilitative programmes in this category of patients. Moreover, the changes in the killing activity of neutrophilic turned out to be more pronounced in a young age group. In this connection, immunomodulating therapy should be strictly differentiated.