Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
J Biophotonics ; 17(7): e202300475, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38866730

RESUMO

The study encompasses an investigation of optical, photothermal and biocompatibility properties of a composite consisting of golden cores surrounded by superparamagnetic CoFe2O4 nanoparticles. Accompanied with the experiment, the computational modeling reveals that each adjusted magnetic nanoparticle redshifts the plasmon resonance frequency in gold and nonlinearly increases the extinction cross-section at ~800 nm. The concentration dependent photothermal study demonstrates a temperature increase of 8.2 K and the photothermal conversion efficiency of 51% for the 100 µg/mL aqueous solution of the composite nanoparticles, when subjected to a laser power of 0.5 W at 815 nm. During an in vitro photothermal therapy, a portion of the composite nanoparticles, initially seeded at this concentration, remained associated with the cells after washing. These retained nanoparticles effectively heated the cell culture medium, resulting in a 22% reduction in cell viability after 15 min of the treatment. The composite features a potential in multimodal magneto-plasmonic therapies.


Assuntos
Cobalto , Compostos Férricos , Ouro , Nanocompostos , Terapia Fototérmica , Nanocompostos/química , Cobalto/química , Cobalto/farmacologia , Ouro/química , Ouro/farmacologia , Compostos Férricos/química , Humanos , Sobrevivência Celular/efeitos dos fármacos , Temperatura
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA