Expert opinion: what to do when there is Coccidioides exposure in a laboratory.

Inadvertent exposure to Coccidioides species by laboratory staff and others as a result of a mishap is not an uncommon cause of infection in clinical microbiology laboratories. These types of infection may occur in laboratories outside the endemic areas, because the etiologic agent is unexpected in the submitted specimens and because personnel may be unfamiliar with the hazards of dealing with Coccidioides species in the laboratory. Coccidioidal infections are often difficult to treat, and outcomes can be poor. Here, we emphasize prevention and an approach to a laboratory accident that minimizes the risk of exposure to laboratory staff and staff in adjacent areas. On the basis of an artificially large exposure to arthroconidia that may occur as a result of a laboratory accident, a conservative approach of close observation and early treatment of exposed staff is discussed.

Saccharomyces cerevisiae as a vaccine against coccidioidomycosis.

Disseminated coccidioidomycosis is a life-threatening infection. In these studies, we examined protection against systemic murine coccidioidomycosis by vaccination with heat-killed Saccharomyces cerevisiae (HKY). CD-1 mice received HKY subcutaneously or by oral gavage with or without adjuvants once weekly beginning 3 or 4 weeks prior to infection; oral live Saccharomyces was also studied. All HKY sc regimens were equivalent, prolonging survival (P

Esferulina y coccidioidina: reacciones cruzadas con la histoplasmina y la paracoccidioidina en pruebas de sensibilidad cutánea / Spherulin and coccidioidin: cross-reactions in dermal sensitivity to histoplasmin and paracocciodioidin

Este estudio presenta los resultados obtenidos -incluyendo los datos sobre las pruebas cutáneas con coccidioidina y paracoccidioidina- respecto de la reactividad a la esferulina, en poblaciones provenientes de zonas en las que la histoplasmosis, si bien no la coccidioidomicosis, es endémica (AU)

Sensibilidad dérmica a diferentes dosis de esferulina y coccidioidina / Dermal sensitivity to different doses of spherulin and coccidioidin

Este estudio revela la mayor eficacia de la esferulina, comparada con la coccidioidina, en la detección de la sensibilidad al C. immitis con fines epidemiológicos (AU)

Esferulina y coccidioidina: reacciones cruzadas con la histoplasmina y la paracoccidioidina en pruebas de sensibilidad cutánea / Spherulin and coccidioidin: cross-reactions in dermal sensitivity to histoplasmin and paracocciodioidin

Este estudio presenta los resultados obtenidos -incluyendo los datos sobre las pruebas cutáneas con coccidioidina y paracoccidioidina- respecto de la reactividad a la esferulina, en poblaciones provenientes de zonas en las que la histoplasmosis, si bien no la coccidioidomicosis, es endémica (AU)

The mycoses as a potentital public health problem in the trans-Amazon highway region

Meeting of the Advisory Committe on Medical Research, 13. Pan American Health Organization; 24-28 Jun. 1974

Field trial of spherulin: a new diagnostic reagent in coccidioidomycosis

Meeting of the Advisory Committee on Medical Research, 11. Pan American Health Organization; 19-23 Jun. 1972

Sensibilidad dérmica a diferentes dosis de esferulina y coccidioidina / Dermal sensitivity to different doses of spherulin and coccidioidin

Este estudio revela la mayor eficacia de la esferulina, comparada con la coccidioidina, en la detección de la sensibilidad al C. immitis con fines epidemiológicos (AU)