[Clinical trials of Xingnao Kaiqiao needling combined with respiratory training for post-stroke dysphagia].

OBJECTIVE: To observe the clinical effect of Xingnao Kaiqiao needling combined with respiratory training on swallowing function, quality of life and throat surface muscle function in patients with post-stroke dysphagia. METHODS: A total of 124 patients with post-stroke dysphagia were randomized into an observation group and a control group, 62 cases in each group. On the basis of conventional western medication treatment, respiratory training was applied in the control group, once daily, 5 times a week for 4 weeks. On the base of the treatment as the control group, Xingnao Kaiqiao needling was applied at Neiguan (PC6), Sanyinjiao (SP6), Fengchi (GB20), Wangu (GB12), Yifeng (SJ17), posterior pharyngeal wall, Shuigou (GV26) and Lianquan (CV23) in the observation group, once daily, 6 times a week for 4 weeks. Before and after treatment, the Kubota water swallowing test (KWST) scale, swallowing function, swallowing-quality of life (SWAL-QOL) scale, maximum amplitude of pharyngeal surface electromyography (sEMG), and complications of dysphagia were observed and recorded. RESULTS: After the treatment, self-comparison showed that the KWST and swallowing function scores were significantly decreased (P<0.05), the SWAL-QOL score and sEMG were notably increased in both groups (P<0.05) in comparison with their own pre-treatment. The KWST and swallowing function scores were obviously lower in the observation group than in the control group (P<0.05), whereas the SWAL-QOL score and sEMG were evidently higher in the observation group than in the control group (P<0.05). The total effective rate of the observation group was 95.16% (59/62), which was higher than 80.65% (50/62) of the control group (P<0.05). The incidence of dysphagia complications in the observation group was 24.19% (15/62), which was lower than 50.00% (31/62) of the control group (P<0.01). CONCLUSION: Xingnao Kaiqiao needling combined with respiratory training in the treatment of post-stroke dysphagia can increase the activity of throat muscles, promote the swallowing function, improve the quality of life, and reduce the incidence of dysphagia related complications.

Effect of danzhi xiaoyao pill on ovulation induction of polycystic ovarian syndrome patients of pathogenic fire derived from stagnation of gan-qi / 中国中西医结合杂志

<p><b>OBJECTIVE</b>To observe the efficacy of Danzhi Xiaoyao Pill (DXP) in anovulation infertility patients with polycystic ovary syndrome (PCOS) of pathogenic fire derived from stagnation of Gan-qi (PFDSG) complicated insulin resistance (IR).</p><p><b>METHODS</b>Sixty PCOS patients were randomly assigned to two group, the integrative medical treatment group (Group A) and the Western medical treatment group (Group B), 30 cases in each group. All patients took Metformin and Diane-35. Those in Group A took DXP additionally. The therapeutic course for all was 3 menstrual cycles. After treatment the ovulation was induced by oral administration of letrozole or injection of menotropins (HMG). The therapeutic efficacy was compared between the two groups.</p><p><b>RESULTS</b>The levels of insulin, luteinizing hormone, and testosterone were obviously lower after treatment than before treatment in the two groups (P < 0.05). There was no statistical difference between the two groups after treatment. There was no statistical difference in body mass index (BMI) between the two groups before and after treatment (P > 0.05). Better effects were obtained in Group A in improving symptoms such as agitation and irritability, fullness in the chest and hypochondrium, swollen pain in the breast before menstruation, bitter and dry mouth, oligomenorrhea, abnormal color and amount of menstruation, and pulse and tongue (P < 0.05, P < 0.01). The ovulation rate was 86.1% (93/108 cases) in Group A, obviously higher than that in Group B (65.5%, 74/113 cases). The clinical pregnancy rate was 60.0% (18/30 cases) in Group A, obviously higher than that in Group B (36.7%, 11/30 cases), showing statistical difference (P < 0.05).</p><p><b>CONCLUSIONS</b>DXP could improve the ovulation rate and the pregnancy rate in anovulation infertility patients with PCOS complicated IR. It also could significantly improve Chinese medical syndromes, showing obvious advantages over using Western medicine alone.</p>