[Clinical study of electroacupuncture therapy on postoperative rehabilitation of patients with knee fractures].

OBJECTIVE: To investigate the effect of electroacupuncture therapy on postoperative rehabilitation training of patients with knee fractures. METHODS: Patients with knee fractures from July 2020 to July 2021 were randomly assigned to either the experimental group or a control group according to the double-blind principle. Both groups were given surgical treatment and postoperative conventional rehabilitation training. There were 40 cases in the control group, including 27 males and 13 females;the age ranged from 20 to 66 years old with an average of (36.46±6.29) years old, continuous passive motion (CPM) training was performed after operation. There were 40 patients in the experimental group, including 24 males and 16 females. The age ranged from 21 to 68 years old with an average of (37.62±7.08) years old, on the basis of the control group, electroacupuncture was given. After 4 weeks of intervention, the excellent rate of knee function score, visual analogue scale (VAS) before and after intervention, serum pain mediators, prostaglandin E (PGE), substance P (SP), bradykinin (BK), joint range of motion and quality of life were compared between the two groups. RESULTS: After 4 weeks of intervention, the Rasmussen score for knee function in the experimental group (24.15±1.36) scores was higher than that in the control group (21.25±2.20) scores (P<0.001). The VAS in the experimental group (2.04±0.51) scores was lower than that in the control group (2.78±0.60) after 4 weeks of intervention (P<0.05). Serum PGE (2.25±0.37) mg·L-1, SP (4.43±1.05) ng·ml-1, BK (2.67±0.68) ng·ml-1 in the experimental group were lower than those in the control group (3.91±0.44) mg·L-1, (6.12±1.37) ng·ml-1, (4.55±1.03) ng·ml-1 after 4 weeks of intervention(P<0.05);in the experimental group, the active knee flexion angle of the knee joint was (108.63±9.76)°, the active knee extension angle (-2.46±0.70)°, passive knee flexion angle (116.83±6.57)°, passive knee extension angle (1.44±0.38)° were better than control group (100.24±8.15)°, (-3.51±0.86)°, (111.04±8.22)°, (0.78±0.24)° (P<0.05);the experimental group's psychological score (73.12±5.08), physiological score (72.26±5.89), social function score (72.57±4.23), overall health score (75.12±5.16) were higher than that of the control group (68.49±4.13), (68.13±5.27), (69.04±3.42), and(70.88±3.97) respectvely(P<0.05). CONCLUSION: Electroacupuncture combined with CPM training after knee fracture surgery can significantly improve knee function and range of motion, reduce pain levels, and also improve quality of life and reduce the incidence of adverse events.

Application Progress of the Case Teaching Method in Standardized Training for Rehabilitation Nurses.

Context: In China, the dearth of adept rehabilitation nurses has escalated into a pressing concern. Conventional nursing education has stymied nurses' autonomous scholarly pursuits. The case-teaching methodology can augment students' competencies and zeal, culminating in the enrichment of educational excellence. Objective: The study intended to elucidate the principles, taxonomy, and enactment of the case-teaching methodology and examine its salutary impacts on nursing practitioners and educators. Design: The research team performed a narrative review by searching BMJ Best Practice, OVID EBM, NGC et al databases. The search used the keywords 'Rehabilitation nursing', 'nursing', 'case teaching method'. Setting: The study took place at the Rehabilitation Medicine Center at West China Hospital of Sichuan University in Chengdu, China. Results: The current study scrutinizes the assimilation of the case-teaching methodology within the realm of nursing, dissects emerging paradigms in the standardized training of rehabilitation nursing staff, and furnishes precedents for the evolution of training frameworks in the field of rehabilitative care. Conclusions: The case-teaching methodology not only serves as an instructional tool but also embodies a fundamental transformation in the modernization of nursing education, embodying the aspiration for excellence, the desire for continuous improvement, and a dedication to the highest standards of patient care.

Effectiveness of Enhanced Recovery After Surgery-Based Respiratory Function Exercise in Elderly Patients with Lung Cancer and its Effect on Postoperative Functional Recovery.

Objective: To investigate the effect of enhanced recovery after surgery-based respiratory function exercise in elderly lung cancer patients and its impact on postoperative functional recovery. Methods: A total of 109 elderly lung cancer patients admitted to our hospital between January 2020 and January 2021 were included in the study. The patients were randomly assigned to either the control group (n = 52), receiving conventional care, or the research group (n = 57), receiving enhanced recovery after surgery-based respiratory function exercise in addition to conventional care. Respiratory function, functional capacity, quality of life, and incidence of pulmonary complications were compared between the two groups before and after the intervention. Results: Following the intervention, the research group showed significant improvements in Forced Expiratory Volume in the first second, Forced Vital Capacity, and Forced Expiratory Volume in the first second/Forced Vital Capacity compared to the control group (P < .05). The research group also exhibited higher Barthel indices (indicating better functional capacity) and lower St George's Respiratory Questionnaire scores (indicating better quality of life) compared to the control group (P < .05). The incidence of pulmonary complications was significantly lower in the research group (5.26%) compared to the control group (21.15%) (P < .05). Conclusions: Enhanced recovery after surgery-based respiratory function exercise can improve respiratory function, promote postoperative functional recovery, enhance the quality of life, and reduce pulmonary complications in elderly lung cancer patients. These findings support its clinical application and wider adoption.

Antibody responses to SARS-CoV-2 in healthy individuals returning to Shenzhen.

To verify reliability of antibody detection and investigate population immunity to severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) in the local Chinese population. A cross-sectional study was conducted in Shenzhen to detect anti-coronavirus antibodies including, immunoglobulin G (IgG), immunoglobulin M (IgM), and immunoglobulin A (IgA). In the COVID-19 group, nine patients were enrolled after diagnosis. In the control group, 1589 individuals without clinical symptoms (cough, fever, and fatigue) and returning from outside Shenzhen were enrolled. The first study enrollment occurred at the end of February 2020; the final study visit was 18 March 2020. In the COVID-19 group, the seven of nine patients were positive for IgM, IgG, and IgA. Meanwhile, six of the 1589 healthy individuals were found to be weakly positive for IgG. According to SARS-CoV-2 nucleic acid tests, the six individuals were all negative. Strong supplemental support for clinical information can be provided by antibody detection, especially for IgA. According to comparison with overseas reports, the infection rate of the Chinese population outside Shenzhen, China, is significantly low, so most of the population in China is still susceptible. Hence, social distancing measures are still inevitable until a vaccine is developed successfully.

[Exploring the sensitive indicators of uterotrophic assay in immature SD rats exposed to para-nonylphenol].

OBJECTIVE: To investigate the estrogenic activity of para-nonylphenol in immature SD rats and explore the mechanism and sensitive indicators of its action in uterotrophic assay. METHODS: The vehicle control (peanut oil), positive control(estradiol benzoate, E2B, 0.4 mg/kg) and p-NP(60 mg/kg, 90 mg/kg and 120 mg/kg) were given orally (by gavage) q.d. on the 21st, 22nd, 23rd postnatal days. Then the rats were sacrificed 24 hours after the last administration. By using ABC immunohistochemistry, the progesterone receptor (PR), estrogen receptor (ER), and proliferating cell nuclear antigen (PCNA) of the rat uterine were analysed. RESULTS: Uterine weight, uterine/body weight significantly increased in E2B 0.4 mg/kg, p-NP 90 mg/kg and 120 mg/kg groups as compared with those of vehicle control group (P < 0.01), and a dose-response relationship was observed. The expressions of PR, ER and PCNA in the nuclei of stromal and myometrial cells of uterus were detected in all the p-NP groups, and a dose-effect relationship was noted. CONCLUSION: Expressions of PR, ER and PCNA as indicators tested by immunohistochemical technique are more sensitive than uterine weight in uterotrophic assay. Hyperplasia of stromal and myometrial cells of uterus is the reason why the uterine weight of the rat increased.