Nitrogen and titanium-codoped porous carbon nanocomposites derived from metal-organic framework as cathode to address polysulfides shuttle effects by Ti-assisted N-inhibiting strategy.

To address the problem of shutting effect of Li-S batteries, we used Ti-based MOF as precursor to obtain a conductive matrix with dual inhibitors. The target material, namely NTiPC, shown remarkable discharge capacity with 1178 mA h g-1, and maintained at 732 mA h g-1 after 100 cycles. The results indicated the N- and Ti-active sites synergistic acted with conductive framework can facilitate binding reaction between matrix and polysulfides.

Neonatal myofibrillar myopathy type II associated with biallelic UNC-45B gene novel mutation and perinatal myasthenia as the core phenotype: A case report.

Myofibrillar myopathy (MFM) is characterized by phenotypic heterogeneity; decreased function of the myosin-directed chaperone, UNC-45B protein, leads to MFM II, which is characterized by slow progressive proximal myasthenia. Currently, only two studies have reported 11 cases worldwide. This study aimed to conduct genetic research and etiological analysis of a neonatal case of perinatal myasthenia who eventually died due to autonomic dyspnea. The case involved a newborn female admitted for weak cries and groaning. Physical examination revealed shallow and irregular spontaneous breathing, difficulty feeding, hip flexion and knee flexion in both lower limbs, hypotonia (level 1), less translation action, and inability to resist gravity. The child died at 23 days after birth. Gene testing, mutation analysis, and crystal structure analysis were conducted. Cell culture and plasmid construction were conducted, followed by western blot analysis. Pathological changes, including Z-line breakage, were observed in the muscle biopsies of different tissues. Gene testing showed that UNC-45B had a novel compound heterozygous mutation (c.2357T>A/p.Met786Lys, c.2591A>C/p.His864Pro), and in vitro functional experiments showed that the variants could lead to a decrease in protein expression. This study expands the UNC-45B mutation and phenotype spectrum by reporting an MFM II case in a Chinese patient for the first time.

[Experimental study on high alloy steel sample by laser-induced breakdown spectroscopy].

The laser-induced breakdown spectroscopy (LIBS) technique is a fast, non-contact method with no need for any sample preparation, and can be carried out under various atmospheric conditions. These properties make LIBS applicable to process control in metallurgy. In the present paper, a series of high alloy steel GBW01605-01609 samples were determined by laser induced plasma spectroscopy, based on a Nd : YAG Q-switched solid laser with wavelength 1 064 nm as an excitation source and CCD as detector. Experimental study on the interaction between laser and high alloy steel samples was completed. The effects on LIBS in high alloy steel such as observation distance and laser power density were systematically studied. The time-resolved spectrum of LIBS was also investigated. The optimum experiment conditions for the application of LIBS to the trace analysis in high alloy steel were obtained firstly.