Correlation between growth rate of corpus callosum and neuromotor development in preterm infants / 中国当代儿科杂志

<p><b>OBJECTIVE</b>To investigate the growth rate of corpus callosum by cranial ultrasound in very low birth weight preterm infants and to provide a reference for early evaluation and improvement of brain development.</p><p><b>METHODS</b>A total of 120 preterm infants under 33 weeks' gestation were recruited and divided into 26-29(+6) weeks group (n=64) and 30-32(+6) weeks group (n=56) according to the gestational age. The growth rate of corpus callosum was compared between the two groups. The correlation between the corpus callosum length and the cerebellar vermis length and the relationship of the growth rate of corpus callosum with clinical factors and the neuromotor development were analyzed.</p><p><b>RESULTS</b>The growth rate of corpus callosum in preterm infants declined since 2 weeks after birth. Compared with the 30-32(+6) weeks group, the 26-29(+6) weeks group had a significantly lower growth rate of corpus callosum at 3-4 weeks after birth, at 5-6 weeks after birth, and from 7 weeks after birth to 40 weeks of corrected gestational age. There was a positive linear correlation between the corpus callosum length and the cerebellar vermis length. Small-for-gestational age infants had a low growth rate of corpus callosum at 2 weeks after birth. The 12 preterm infants with severe abnormal intellectual development had a lower growth rate of corpus callosum compared with the 108 preterm infants with non-severe abnormal intellectual development at 3-6 weeks after birth. The 5 preterm infants with severe abnormal motor development had a significantly lower growth rate of corpus callosum compared with the 115 preterm infants with non-severe abnormal motor development at 3-6 weeks after birth.</p><p><b>CONCLUSIONS</b>The decline of growth rate of corpus callosum in preterm infants at 2-6 weeks after birth can increase the risk of severe abnormal neuromotor development.</p>

Alcohol-processable organic amorphous electrolytes as an effective electron-injection layer for organic light-emitting diodes.

A new series of monoammonium-based organic electrolytes with the tetrafluoroborate (BF(4)(-)) counteranion have been synthesized. Replacing the pendant ethyl groups in the fluorenyl unit with 4-ethoxyphenyl groups dramatically improves both solubility and morphological stability. The characterization of the alcohol-processable amorphous ionic compounds as an electron-injection layer in organic light-emitting diodes (OLEDs) reveals that the organic electrolyte that comprises a rigid linear-conjugated unit provides better device performance, with respect to its counterpart containing a branched bulky moiety. The capability of these compounds to facilitate electron injection from air-stable aluminum metal is preliminarily discussed on the basis of the investigations of the electron-only devices and photovoltaic experiments.