Mindfulness-Based Movement Intervention to Improve Sleep Quality: A Meta-Analysis and Moderator Analysis of Randomized Clinical Trials.

(1) Background: Given that the most effective dose, optimal type, and most beneficial population for improving sleep with mindfulness-based movement (MBM) remains unknown, we conducted a systematic review and meta-analysis with moderator analysis of randomized controlled trials (RCTs) to assess these effects. (2) Methods: Three electronic databases (PubMed, Web of Science, and EBSCO) were systematically searched for RCTs published through August 2021 for analysis. The risk of bias of the included studies was assessed with Review Manager 5.3, and the meta-analysis was performed in Stata 16.0. (3) Results: A meta-analysis of 61 RCTs with 2697 participants showed that MBM significantly improved sleep quality compared to controls (SMD = −0.794; 95% CI: −0.794 to −0.994, p < 0.001, I2 = 90.7%). Moderator analysis showed that a long-term MBM (SMD = −0.829; 95% CI: 0.945 to 0.712; p < 0.001) had a larger effect size on sleep than a short-term MBM (SMD = −0.714; 95% CI: 0.784 to 0.644; p < 0.001). Practicing at least twice per week (SMD = −0.793; 95% CI: −0.868 to −0.718; p < 0.001) was more effective compared to practicing once per week (SMD = −0.687; 95% CI: −0.804 to −0.570; p < 0.001). Studies with a total intervention time of more than 24 h also revealed better sleep quality improvement (SMD = −0.759; 95% CI: −0.865 to −0.653; p < 0.001). In addition, the healthy population and older adults gained more from MBM than the patients and younger adults. (4) Conclusions: MBM can effectively improve subjective sleep quality, and the optimal intervention dose of MBM can be utilized in future intervention studies to treat or improve sleep disturbance (MBM more than twice a week for more than three months, with a total intervention time of more than 24 h).

Differences in School Performance Between Only Children and Non-only Children: Evidence From China.

This study aimed to investigate the features of only child status related to physical health, mathematics achievement, and school feelings and expectations from a different perspective. A representative sample of 91,619 Grade 4 students with an average age of 10.4 ± 0.7, among which 28,631 were only children, were assessed. We used propensity score matching (PSM) and the average treatment effects on the treatment to analyze data. The treatment was the only child of a family. The results indicated that only children have better academic achievement and school feelings (only for urban only child girls), while non-only children have better physical status and anaerobic fitness (AF). In addition, gender and rural vs. urban areas differences were also explored. The adverse situation for rural only boys is emphasized for families, researchers, and governments to focus on. Some suggestions are given under the Two- and Three-Child Policy.

Associations between Poor Vision, Vision-Related Behaviors and Mathematics Achievement in Chinese Students from the CNAEQ-PEH 2015.

Purpose: Poor vision is prevalent in school-aged students, especially in East Asia. This can not only cause irreversibly physical health impairments like glaucoma and cataracts, but also the loss of individual education and employment opportunities and deterioration of the quality of life. The present study aims to investigate the associations between poor vision, vision-related risk behaviors, and mathematics achievement in youth from China. Methods: The present study included a total of 106,192 Grade 4 students and 70,236 Grade 8 students from the China National Assessment of Educational Quality-Physical Education & Health 2015 (CNAEQ-PEH 2015). We conducted a standard logarithmic visual acuity scale for vision screening, a self-reported questionnaire for vision-related risk behavior and a standardized mathematics assessment for mathematics performance. Poor vision is defined as the visual acuity below 5.0 by using the standard logarithmic visual acuity chart. Linear regression was conducted. Results: The prevalence rate of poor vision in China was 37.1% in Grade 4 and 66.2% in Grade 8 in 2015. Students who had poor vision were more likely to have better mathematics achievement than those with normal vision. Reading in bed, insufficient sleep, and screen time during weekdays and weekends were associated with higher odds of poor vision. Conclusions: Poor vision was positively associated with mathematics academic achievements, while vision-related risk behaviors such as screen time, homework time and reading in bed were associated with a high prevalence of poor vision in compulsory education cycle students.

"No Pain No Gain": Evidence from a Parcel-Wise Brain Morphometry Study on the Volitional Quality of Elite Athletes.

Volition is described as a psychological construct with great emphasis on the sense of agency. During volitional behavior, an individual always presents a volitional quality, an intrapersonal trait for dealing with adverse circumstances, which determines the individual's persistence of action toward their intentions or goals. Elite athletes are a group of experts with superior volitional quality and, thereby, could be regarded as the natural subject pool to investigate this mental trait. The purpose of this study was to examine brain morphometric characteristics associated with volitional quality by using magnetic resonance imaging (MRI) and the Scale of Volitional Quality. We recruited 16 national-level athletes engaged in short track speed skating and 18 healthy controls matched with age and gender. A comparison of a parcel-wise brain anatomical characteristics of the healthy controls with those of the elite athletes revealed three regions with significantly increased cortical thickness in the athlete group. These regions included the left precuneus, the left inferior parietal lobe, and the right superior frontal lobe, which are the core brain regions involved in the sense of agency. The mean cortical thickness of the left inferior parietal lobe was significantly correlated with the independence of volitional quality (a mental trait that characterizes one's intendency to control his/her own behavior and make decisions by applying internal standards and/or objective criteria). These findings suggest that sports training is an ideal model for better understanding the neural mechanisms of volitional behavior in the human brain.

Phytic Acid Contents and Metabolite Profiles of Progenies from Crossing Low Phytic Acid OsMIK and OsMRP5 Rice (Oryza sativa L.) Mutants.

The impact of cross-breeding two low phytic acid (lpa) rice mutants on the content of phytic acid and the metabolite profile of the resulting double mutant was investigated. Progenies resulting from the cross of Os-lpa-XS110-1, a rice mutant carrying the myo-inositol kinase (OsMIK) mutated gene, and Os-lpa-XS110-2, with the multidrug resistance-associated protein ABC transporter gene 5 (OsMRP5) as the mutation target, were subjected to high-pressure ion chromatography. The reduction of the phytic acid content in the double mutant (-63%) was much more pronounced than in the single mutants (-26 and -47%). Gas chromatography-based metabolite profiling revealed a superimposition of the metabolite profiles inherited from the lpa progenitors in the double mutant progenies; the resulting metabolite signature was predominated by the OsMIK mutation effect. The study demonstrated that cross-breeding of two single lpa mutants can be employed to generate double lpa rice mutants showing both a significant reduction in the content of phytic acid and the imprinting of a specific mutation-induced metabolite signature.

Relationship of Physical Education Curriculum Implementation and Mathematics Achievement in Chinese Youth.

PURPOSE: Previous studies indicated a positive association between physical education (PE) and mathematics achievement (MA). This study explored how PE curriculum implementation relates to MA using data from the China National Assessment of Education Quality (CNAEQ) in 2015, including Mathematics (CNAEQ-MA 2015) as well as Physical Education & Health (CNAEQ-PEH 2015). METHOD: This study included 22,619 students (48.7% girls) age 13.96 ± 0.64 yr. from the national sample of Grade 8 students from CNAEQ. During 2015, MA and cardiorespiratory fitness (CF) were assessed. PE curriculum implementation, personal hygiene, eating habits, PE interest, mathematics interest, and self-confidence were collected via a self-report student survey. Personal hygiene and eating habits were combined to create the latent variable, healthy lifestyle (HL). Structural equation modeling was applied to examine the associations. Socioeconomic status, school location, Body Mass Index (BMI), and sex were all controlled. RESULTS: PE curriculum implementation had an indirect, positive association with MA through CF, HL-mathematics interest, and HL-mathematics self-confidence. Together, the model explained 27.8% of the variance in MA. CONCLUSION: PE curriculum implementation may benefit mathematics education, and this link is mainly through HL, CF, mathematics interest, and self-confidence.

China National Assessment of Education Quality - Physical Education & Health (CNAEQ-PEH) 2015: An Introduction.

PURPOSE: To summarize the framework and development procedure of the China National Assessment of Education Quality - Physical Education & Health in 2015 (CNAEQ-PEH 2015), an authoritative and evidence-based national surveillance protocol developed by the Ministry of Education of the People's Republic of China for Grade 4 and Grade 8 students. METHODS: The framework of CNAEQ-PEH 2015 included a test battery of physical fitness and health outcomes and self-reported questionnaires regarding facilitators and barriers to physical fitness and health in school settings and family status, completed by students, teachers, and principals. A qualified, standardized, and responsible work procedure was generated to provide insights into the quality of data collection and supervision of large-scale school-based physical fitness testing implementation. Measure development, stratified unequal probability sampling, and implementation were included in the working procedure. RESULTS: In the first circle of the CNAEQ-PEH conducted on June 18, 2015, 111,173 Grade 4 students from 4,015 elementary schools and 72,243 Grade 8 students from 2,461 middle schools, along with their principals (n = 6,447) and physical education (PE) teachers (n = 11,418), were sampled by probability proportionate to size (PPS) across 323 counties in China. Results provided detailed information regarding students' physical fitness outcomes, learning, lifestyle, and educational environment. CONCLUSIONS: CNAEQ-PEH 2015 is a large-scale assessment of physical fitness and health outcomes. It helps provide opportunities to understand the physical fitness and health status of Chinese Grade 4 and 8 students and to study the correlations of physical fitness and health, as well as their relationship with education-related indicators and academic performance.

Associations Among Physical Education, Activity-Related Healthy Lifestyle Practices, and Cardiorespiratory Fitness of Chinese Youth.

PURPOSE: Physical education (PE) in school provides opportunities for physical activity (PA) engagement and reportedly results in improved health-related fitness. This study explored the underlying correlations between PE and activity-related healthy lifestyle practices with current level of cardiorespiratory fitness. METHODS: A total of 13,138 students age 14 (boys = 7,094, 54.0%) in Grade 8 from the China National Assessment of Educational Quality - Physical Education & Health 2015 were included in this study. Two independent structural equation modeling (SEM) analyses were conducted to obtained sex-specific results. Data included the results of the 15-m progressive aerobic cardiovascular endurance run (PACER) and questionnaire data regarding PE curriculum implementation, learning and practice, perceived support from PE teachers, PE facilities, PE equipment, activity-related healthy lifestyle practices, habitual physical fitness, appropriate method of physical fitness, and breakfast eating habits. Structural equation modeling was applied to examine the associations between variables, controlling for socioeconomic status, the location of schools, and Body Mass Index. RESULTS: There was a statistically significant relationship between cardiorespiratory fitness and activity-related healthy lifestyle practices, which was somewhat positively impacted by skill learning and practice and perceived support from PE teachers. Together, the boy's model explained 21.8% of the variance in cardiorespiratory fitness, whereas the girl's model explained 15.9%. CONCLUSIONS: A well-organized PE program is related to students' activity-related healthy lifestyle practices, and consequently provides an improvement to cardiorespiratory fitness.

The Relationships Between Weight Status and Physical Fitness Among Chinese Children and Youth.

PURPOSE: This study examined the prevalence of different weight status and the relationships between weight status and physical fitness among Chinese children and youth. METHODS: Participants were 107,206 Grade 4 children and 70,213 Grade 8 youth from the China National Assessment of Educational Quality - Physical Education & Health in 2015 (CNAEQ-PEH 2015). Using World Health Organization (WHO) and US Centers for Disease Control and Prevention (CDC) criteria, weight status was divided into four groups (underweight, normal weight, overweight, and obese) according to Body Mass Index (BMI). The differences of physical fitness performances (15-m progressive aerobic cardiovascular endurance run [PACER], standing long jump, and 50-m sprint) among four weight status groups were compared. Data were analyzed using descriptive statistics, MANCOVA, and Cohen's d. RESULTS: The prevalence of weight status varied by criteria (e.g., for Grade 4 boys, the prevalence of underweight by WHO and CDC were 5.9% and 10.5%; overweight were 14.5% and 11.4%, respectively). Compared with the normal weight group, the selected physical fitness performances in the overweight and obese groups were worse (p < .001) with small to large effect sizes. CONCLUSION: The prevalence of underweight and overweight/obese was relatively high among Chinese children and youth. The prevalence of underweight, overweight, and obesity varied slightly depending on the criteria used for evaluating BMI. The overweight/obese participants tended to perform poorer in selected physical fitness tests. The performance disparities between the normal weight group and overweight/obese groups were larger in Grade 4 than in Grade 8 and among boys than among girls.

Impact of Crossing Parent and Environment on the Metabolite Profiles of Progenies Generated from a Low Phytic Acid Rice ( Oryza sativa L.) Mutant.

The low phytic acid ( lpa) rice mutant Os-lpa-MH86-1, exhibiting a mutation-induced metabolite signature (i.e., increased levels of sugars, sugar alcohols, amino acids, phytosterols, and biogenic amines), was crossed with two commercial wild-type cultivars. The resulting progenies of generation F8 harvested at three independent field trials were subjected to a GC/MS-based metabolite profiling approach. Statistical assessments via multivariate and univariate analyses demonstrated that the environment had a strong impact on the metabolite profiles of the resulting progenies. In addition, the metabolites of homozygous lpa progenies were significantly influenced by the lipid profiles of the wild-type cultivars employed as the crossing parents. However, for each individual field trial, both the lpa trait and the mutation-specific metabolite signature were consistently expressed in the homozygous lpa mutant progenies of the two crosses. The data underline that cross-breeding can be employed as a tool to generate lpa progeny rice seeds stably exhibiting the mutation-induced metabolic traits.

Stability of the Metabolite Signature Resulting from the OsSULTR3;3 Mutation in Low Phytic Acid Rice ( Oryza sativa L.) Seeds upon Cross-breeding.

The low phytic acid ( lpa) rice ( Oryza sativa L.) mutant Os-lpa-MH86-1, resulting from the mutation of the putative sulfate transporter gene OsSULTR3;3, was crossed with a commercial rice cultivar. The obtained progenies of generations F4 to F7 were subjected to a nontargeted metabolite profiling approach allowing the analyses of a broad spectrum of lipophilic and hydrophilic low-molecular-weight constituents. The metabolite profiles of the homozygous lpa progenies were characterized not only by a decreased concentration of phytic acid but also by increased contents of constituents from various classes, such as sugars, sugar alcohols, amino acids, phytosterols, and biogenic amines. Statistical assessments of the data via multivariate and univariate approaches demonstrated that this mutation-induced metabolite signature was nearly unaffected by the cross-breeding step and consistently expressed over several generations. The data demonstrate that even for complex metabolic changes resulting from a mutation, cross-breeding can be employed as a tool to generate progeny rice seeds stably exhibiting the mutation induced traits.

The Effect of Diaphragmatic Breathing on Attention, Negative Affect and Stress in Healthy Adults.

A growing number of empirical studies have revealed that diaphragmatic breathing may trigger body relaxation responses and benefit both physical and mental health. However, the specific benefits of diaphragmatic breathing on mental health remain largely unknown. The present study aimed to investigate the effect of diaphragmatic breathing on cognition, affect, and cortisol responses to stress. Forty participants were randomly assigned to either a breathing intervention group (BIG) or a control group (CG). The BIG received intensive training for 20 sessions, implemented over 8 weeks, employing a real-time feedback device, and an average respiratory rate of 4 breaths/min, while the CG did not receive this treatment. All participants completed pre- and post-tests of sustained attention and affect. Additionally, pre-test and post-test salivary cortisol concentrations were determined in both groups. The findings suggested that the BIG showed a significant decrease in negative affect after intervention, compared to baseline. In the diaphragmatic breathing condition, there was a significant interaction effect of group by time on sustained attention, whereby the BIG showed significantly increased sustained attention after training, compared to baseline. There was a significant interaction effect of group and time in the diaphragmatic breathing condition on cortisol levels, whereby the BIG had a significantly lower cortisol level after training, while the CG showed no significant change in cortisol levels. In conclusion, diaphragmatic breathing could improve sustained attention, affect, and cortisol levels. This study provided evidence demonstrating the effect of diaphragmatic breathing, a mind-body practice, on mental function, from a health psychology approach, which has important implications for health promotion in healthy individuals.

Tai Chi Chuan modulates heart rate variability during abdominal breathing in elderly adults.

Tai Chi Chuan (TCC) practice is currently intentionally applied in clinical populations, especially those with cardiovascular diseases because of its potential benefits on the autonomic nervous system. The long-term effect of TCC practice on heart rate variability (HRV) remains largely unknown. In this study, we recruited 23 TCC practitioners whose experience averaged approximately 21 years and 19 controls matched by age, sex and education to examine the effect of TCC practice on the autonomic nervous system during a resting state and during an abdominal breathing state. HRV was measured by traditional electrocardiogram (ECG) recording. The results showed that the low frequency, total power frequency, and normalized low frequency components and the low-frequency/high-frequency ratio were significantly higher, whereas the normalized high frequency was significantly lower in the TCC practitioners relative to controls during the abdominal breathing state. However, we did not detect any significant difference in the HRV measures during the resting state between the two groups. Additionally, TCC experience did not correlate with HRV components either in the abdominal state or the resting state in the TCC group. Considering all of these findings, we suggest that TCC improves vagal activity and the balance between sympathetic and parasympathetic activity during the relaxation state. This study also provides direct physiological evidence for the role of TCC practice in relaxation.

A down-regulated epi-allele of the genomes uncoupled 4 gene generates a xantha marker trait in rice.

KEY MESSAGE: A γ-ray-induced xantha trait is epigenetically controlled by the genomes uncoupled 4 gene with enhanced promoter segment methylation and down-regulated expression in rice. For easy testing and to increase varietal purity, a xantha mutation (xnt), which turns plants yellow and makes them visually distinguishable from normal green rice, has been generated and bred into male sterile lines for hybrid rice production. The xnt locus was previously fine mapped to a ~100-kb interval on chromosome 11, but its identity was unknown. In this study, xnt was further narrowed down to a 57-kb fragment carrying eight opening reading frames (ORFs). All eight ORFs had identical genomic sequences and all but ORF2 (g enomes uncoupled 4, OsGUN4) had similar transcript abundance in the xantha mutant Huangyu B (HYB) and its parental variety Longtefu B (LTB). The expression of OsGUN4, however, was significantly reduced in HYB compared with LTB in terms of both transcript abundance (0.2% that of LTB) and expressed protein level (barely detectable in HYB but greater than the heat shock protein reference in LTB). Therefore, OsGUN4 was identified as the candidate gene underlying the xantha trait. The function of OsGUN4 in the xantha phenotype was confirmed by identification and characterization of new allelic OsGUN4 mutations. Comparative bisulfite genomic sequencing of OsGUN4 revealed increased methylation in a promoter region in the mutant, and the correlation between increased methylation and the xantha phenotype was further verified by demethylation treatment. In summary, we have identified an epi-allele of OsGUN4 as the causal gene of the xantha marker trait and revealed that enhanced methylation in its promoter down-regulated its expression in rice.

Regional inflation of the thalamus and globus pallidus in diving players.

PURPOSE: Several recent studies have identified structural changes in the cerebral cortex that occur with extensive motor training. However, limited studies have been conducted to explore the structural changes of subcortical structures, which are thought to play important roles in motor functioning. This study aims to localize the shape differences of the subcortical structures between the diving players and the nonathlete group. METHODS: Twelve professional players with top-level diving skills and 12 age- and education-matched healthy controls without any training experience were scanned with a 3-T magnetic resonance imaging. Data were processed using FSL-FIRST, a model-based segmentation and registration tool. RESULTS: Compared with the nonathlete group, we found significant regional inflation in the bilateral thalamus and the left globus pallidus in diving players. CONCLUSION: Although we cannot rule out the effect of predispositions, the regional inflation of the thalamus and globus pallidus might reflect the experience-dependent plasticity because of extensive diving training.