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1.
Rev Esp Quimioter ; 29(4): 214-9, 2016 Aug.
Artigo em Espanhol | MEDLINE | ID: mdl-27341025

RESUMO

OBJECTIVE: Prosthetic late infection occurs in the second month after surgery in the context of haematogenous spread from another source. Prosthetic mycobacterial infection is a rare complication whose clinical management is not standardized. CASE: Patient of 77 years with no personal history except for diabetes and a prosthetic replacement of right knee with osteoarthritis three years ago. Patient goes to hospital emergency box for 6 months pain in the right knee with mechanical inflammatory signs but no fever associated. After their return within 5 days and clinical worsening is reporting growth of Mycobacterium tuberculosis in knee aspirate and antitubercular treatment is established for 9 months. Nuclear magnetic resonance imaging studies also confirmed the diagnosis of tuberculosis spondylitis in the clinical context of the patients. After surgery, M. tuberculosis was again isolated from intraoperative samples and therefore the patient received another batch of treatment for 9 months. After a year of monitoring, the development was acceptable but few months later, the patient died for cardiovascular causes. In the literature review, 15 publications with a total of 17 clinical cases of prosthetic infection by M. tuberculosis were found from 1980 to 2014. CONCLUSIONS: Prosthetic tuberculous arthritis, although it is a rare presentation, it should be noted, especially in patients with predisposing conditions with a history of tuberculosis infection.


Assuntos
Antituberculosos/uso terapêutico , Artrite Infecciosa/tratamento farmacológico , Articulação do Joelho , Infecções Relacionadas à Prótese/tratamento farmacológico , Tuberculose Osteoarticular/tratamento farmacológico , Idoso , Artrite Infecciosa/microbiologia , Evolução Fatal , Feminino , Humanos , Prótese do Joelho , Mycobacterium tuberculosis , Infecções Relacionadas à Prótese/diagnóstico por imagem , Infecções Relacionadas à Prótese/microbiologia , Espondilite/diagnóstico por imagem , Espondilite/tratamento farmacológico , Espondilite/microbiologia , Tuberculose Osteoarticular/diagnóstico por imagem , Tuberculose Osteoarticular/etiologia , Tuberculose Osteoarticular/microbiologia
2.
Transpl Infect Dis ; 17(6): 795-9, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26288113

RESUMO

BACKGROUND: The aim of this article is to assess the seroprevalence of Leishmania infection among asymptomatic renal transplant recipients in a population in the south of Spain. METHODS: Serum samples were screened for immunoglobulin-G antibodies against Leishmania with an indirect fluorescent antibody test. RESULTS: Of 625 examined serum samples, 30 (4.8%) samples were positive for Leishmania antibodies. Thirteen samples showed titers of 1:80, 15 samples showed titers of 1:160, and 2 samples showed titers of 1:320. None of the patients with positive serology to Leishmania showed signs or symptoms compatible with leishmaniasis. CONCLUSION: The prevalence of Leishmania infection found among asymptomatic renal transplant patients reinforces the need for attention in evaluation of these patients in endemic areas.


Assuntos
Transplante de Rim/efeitos adversos , Leishmaniose/sangue , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Anticorpos Antiprotozoários/sangue , Criança , Feminino , Humanos , Leishmaniose/epidemiologia , Masculino , Pessoa de Meia-Idade , Estudos Soroepidemiológicos , Espanha/epidemiologia , Adulto Jovem
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