Effects of Bioactive Dietary Components on Changes in Lipid and Liver Parameters in Women after Bariatric Surgery and Procedures.

Excess adipose tissue, as well as its distribution, correlates strongly with disorders of lipid and liver parameters and chronic inflammation. The pathophysiology of metabolic diseases caused by obesity is associated with the dysfunction of visceral adipose tissue. Effective and alternative interventions such as the Bioenteric Intragastric Balloon and bariatric surgeries such as the Roux-en-Y gastric bypass. The aim of this study was to assess the effect of modifying the recommended standard weight loss diet after bariatric surgery and procedures on reducing chronic inflammation in overweight patients. In the study, bioactive anti-inflammatory dietary components were used supportively. Changes in the concentrations of lipid parameters, liver parameters, antioxidant enzymes, cytokines, and chemokines were demonstrated. The enrichment of the diet, after bariatric surgery, with the addition of n-3 EFAs(Essential Fatty Acids), bioflavonoids, vitamins, and synbiotics resulted in higher weight losses in the patients in the study with a simultaneous reduction in parameters indicating liver dysfunction.

Application of collagen matrix in the prevention of anastomotic leaks following D2 gastrectomy with Roux-en-Y anastomosis.

Esophagoenteral anastomotic leaks are one of the most serious complications of gastric cancer surgeries. Leaking anastomosis has a negative impact on patient's prognosis as it translates into increased reoperation rates, direct and indirect mortality, as well as increased risk of cancer recurrence. Literature contains reports on the use of additional measures aimed at preventing anastomotic leaks. Collagen matrices with tissue adhesives used to prevent anastomotic leaks following D2 gastrectomy with Roux-en-Y anastomosis have not been described well in Polish literature. However, international reports on such use of these materials are available. Collagen matrices have been successfully applied in selected patients undergoing total or subtotal gastrectomy at the Department of General, Minimally Invasive, and Gastroenterological Surgery. We hereby present our experience in a group of 6 patients presenting with anastomotic leak risk factors.