RESUMO
A 33-year-old Indonesian woman presented for follow-up after a recent history of papillary thyroid carcinoma treated with total thyroidectomy and radioiodine therapy. A 131I whole-body scintigraphy showed an elongated iodine accumulation in the right hemithorax. On suspicion of pulmonary metastasis, further diagnostics with 124I PET/CT showed thickening of the bronchial wall and retention of secretion in a middle lobe bronchus. Bronchoscopy and histology allowed a diagnosis of stenosing anthracofibrosis with chronic inflammatory changes.
Assuntos
Brônquios/diagnóstico por imagem , Carcinoma/radioterapia , Radioisótopos do Iodo/efeitos adversos , Compostos Radiofarmacêuticos/efeitos adversos , Neoplasias da Glândula Tireoide/radioterapia , Adulto , Brônquios/patologia , Carcinoma Papilar , Reações Falso-Positivas , Feminino , Fibrose/diagnóstico por imagem , Humanos , Radioisótopos do Iodo/uso terapêutico , Imagem Multimodal , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos/uso terapêutico , Câncer Papilífero da Tireoide , Neoplasias da Glândula Tireoide/patologia , Tomografia Computadorizada por Raios XRESUMO
A precise estimate of thyroid volume is necessary for making adequate therapeutic decisions and planning, as well as for monitoring therapy response. The goal of this study was to compare the precision of different volumetry methods. Thyroid-shaped phantoms were subjected to volumetry via 2-D and 3-D ultrasonography (US), computed tomography (CT) and magnetic resonance imaging (MRI). The 3-D US scans were performed using sensor navigation and mechanical sweeping methods. Volumetry calculation ensued with the conventional ellipsoid model and the manual tracing method. The study confirmed the superiority of manual tracing with CT and MRI volumetry of the thyroid, but extended this knowledge also to the superiority of the 3-D US method, regardless of whether sensor navigation or mechanical sweeping is used. A novel aspect was successful use of the same universally applicable cross-imaging software for all modalities.
Assuntos
Algoritmos , Interpretação de Imagem Assistida por Computador/métodos , Imageamento Tridimensional/métodos , Imagem Multimodal/instrumentação , Imagem Multimodal/métodos , Imagens de Fantasmas , Glândula Tireoide/anatomia & histologia , Humanos , Aumento da Imagem/métodos , Imageamento por Ressonância Magnética/instrumentação , Imageamento por Ressonância Magnética/métodos , Tamanho do Órgão/fisiologia , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Glândula Tireoide/diagnóstico por imagem , Tomografia Computadorizada por Raios X/instrumentação , Tomografia Computadorizada por Raios X/métodos , Ultrassonografia/instrumentação , Ultrassonografia/métodosRESUMO
We report the draft genome sequence of Bacillus anthracis UR-1, isolated from a fatal case of injectional anthrax in a German heroin user. Analysis of the genome sequence of strain UR-1 may aid in describing phylogenetic relationships between virulent heroin-associated isolates of B. anthracis isolated in the United Kingdom, Germany, and other European countries.
Assuntos
Bacillus anthracis/genética , DNA Bacteriano/química , DNA Bacteriano/genética , Genoma Bacteriano , Análise de Sequência de DNA , Antraz/microbiologia , Bacillus anthracis/isolamento & purificação , Alemanha , Heroína/administração & dosagem , Dados de Sequência Molecular , Abuso de Substâncias por Via Intravenosa/complicaçõesRESUMO
Bacillus anthracis BF-1 was isolated from a cow in Bavaria (Germany) that had succumbed to anthrax. Here, we report the draft genome sequence of this strain, which belongs to the European B2 subclade of B. anthracis. The closest phylogenetic neighbor of strain BF-1 is a strain isolated from cattle in France.
Assuntos
Antraz/veterinária , Bacillus anthracis/classificação , Bacillus anthracis/genética , Doenças dos Bovinos/microbiologia , Genoma Bacteriano , Animais , Antraz/epidemiologia , Antraz/microbiologia , Bovinos , Doenças dos Bovinos/epidemiologia , Alemanha/epidemiologia , Dados de Sequência MolecularRESUMO
The shear modulus of the vocal fold is an essential parameter required to enhance our understanding of how the vocal fold operates, to develop mathematical models of phonatation, and to provide benchmarks to quantify the effectiveness of surgical procedures. The authors announced the successful deployment of an instrument to measure vocal fold elasticity in vivo last year, and now present the data taken from eight patients in vivo. The shear modulus was measured at the mid-membranous point, in a transverse direction with respect to the axis drawn between the anterior commissure and vocal process. The range of mean shear modulus results is 701-2,225 Pa, with a mean value of 1,371 Pa.
