RESUMO
Introduction: Two cases of idiopathic granolomatous mastitis were diagnosed by histological examination in our Surgical Department in 2017. The idiopathic granulomatous mastitis is a rare, benign inflammatory laesion of the breast which can mimic malignancy in it's clinical appearance. We would like to draw attention to this differential diagnostic problem based on the cases of our Surgery Department.
Assuntos
Mastite Granulomatosa/patologia , Adulto , Mama/patologia , Neoplasias da Mama/patologia , Diagnóstico Diferencial , Feminino , Mastite Granulomatosa/cirurgia , Humanos , Doenças RarasRESUMO
UNLABELLED: In daily practice mycotic infections of the CNS have become more and more frequent. The main causes are the wide-ranging use of corticosteroids, immunosuppressive, cytostatic drugs and antibiotics, the spreading of AIDS, the increasing number of surviving immature newborns. To illustrate the diagnostic difficulties, the authors report several cases. CASE REPORTS: 1. Multifocal hemorrhagic infarcts of the brain, caused by generalized aspergillosis in mantle cell malignant lymphoma. 2. Cerebral microabscesses, caused by systemic candidiasis in a premature infant. 3. Fatal actinomycosis, mimicking a space occupying tumour in the thigh and with an abscess in the brain, radiologically indicated as a metastasis. The cause of death was actinomycotic pneumonia. 4. A successfully treated and recovered patient with recurrent pneumonia and multiplex brain abscesses, caused by filamentous microorganism of a Nocardia species revealed by histological examination of the neurosurgical specimen. DISCUSSION AND CONCLUSIONS: We have to be aware for the development of the mycotic and related infections of endangered patients. Aspergillosis and candidiasis play the most significant role in the involvement of the central nervous system. Actinomycosis and nocardiosis are more sensitive to treatment, so their diagnosis is of life-saving importance. The therapeutic chances of high risk patients with aspergillosis and candidiasis will be definitively better, if the infection is recognized and appropriately treated before the involvement of the CNS.
Assuntos
Actinomicose/diagnóstico , Encéfalo/microbiologia , Candidíase/diagnóstico , Infecções Fúngicas do Sistema Nervoso Central/diagnóstico , Infecções Fúngicas do Sistema Nervoso Central/microbiologia , Neuroaspergilose/diagnóstico , Nocardiose/diagnóstico , Actinomicose/complicações , Abscesso Encefálico/microbiologia , Candidíase/complicações , Hemorragia Cerebral/microbiologia , Infarto Cerebral/microbiologia , Diagnóstico Diferencial , Evolução Fatal , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Neuroaspergilose/complicaçõesRESUMO
Primary squamous cell carcinoma of the breast is a rare tumor that presents an unique biologic behavior. Thus, it challenges the justification for routine axillary dissection and adjuvant therapy. Squamous cell carcinoma has several unique biologic characteristics; it is associated with a lower rate of lymph node metastasis and significant rate of distant metastasis without lymph node involvement. The diagnosis of primary squamous cell carcinoma of the breast can only be established if the metastatic tumor origin can be excluded, the tumor is not attached to the skin and no other histological type of carcinoma is detected in the course of detailed histological examination. The authors present two cases from their own experience. One of them has preexisted fine needle aspiration cytology.