Correcting Presbyopia With Autofocusing Liquid-Lens Eyeglasses.

OBJECTIVE: Presbyopia, an age-related ocular disorder, is characterized by the loss in the accommodative abilities of the human eye. Conventional methods of correcting presbyopia divide the field of view, thereby resulting in significant vision impairment. We demonstrate the design, assembly and evaluation of autofocusing eyeglasses for restoration of accommodation without dividing the field of view. METHODS: The adaptive optics eyeglasses comprise of two variable-focus liquid lenses, a time-of-flight range sensor and low-power, dual microprocessor control electronics, housed within an ergonomic frame. Subject-specific accommodation deficiency models were utilized to demonstrate high-fidelity accommodative correction. The abilities of this system to reduce accommodation deficiency, its power consumption, response time, optical performance and MTF were evaluated. RESULTS: Average corrected accommodation deficiencies for 5 subjects ranged from -0.021 D to 0.016 D. Each accommodation correction calculation was performed in ∼67 ms which consumed 4.86 mJ of energy. The optical resolution of the system was 10.5 cycles/degree, and featured a restorative accommodative range of 4.3 D. This system was capable of running for up to 19 hours between charge cycles and weighed ∼132 g. CONCLUSION: The design, assembly and performance of an autofocusing eyeglasses system to restore accommodation in presbyopes has been demonstrated. SIGNIFICANCE: The new autofocusing eyeglasses system presented in this article has the potential to restore pre-presbyopic levels of accommodation in subjects diagnosed with presbyopia.

Parametrically Amplified Low-Power MEMS Capacitive Humidity Sensor.

We present the design, fabrication, and response of a polymer-based Laterally Amplified Chemo-Mechanical (LACM) humidity sensor based on mechanical leveraging and parametric amplification. The device consists of a sense cantilever asymmetrically patterned with a polymer and flanked by two stationary electrodes on the sides. When exposed to a humidity change, the polymer swells after absorbing the analyte and causes the central cantilever to bend laterally towards one side, causing a change in the measured capacitance. The device features an intrinsic gain due to parametric amplification resulting in an enhanced signal-to-noise ratio (SNR). Eleven-fold magnification in sensor response was observed via voltage biasing of the side electrodes without the use of conventional electronic amplifiers. The sensor showed a repeatable and recoverable capacitance change of 11% when exposed to a change in relative humidity from 25-85%. The dynamic characterization of the device also revealed a response time of ~1 s and demonstrated a competitive response with respect to a commercially available reference chip.

Creep deformation in elastomeric membranes of liquid-filled tunable-focus lenses.

Liquid-filled tunable-focus lenses have been demonstrated to be suitable for autofocus eyewear applications. Traditionally, these lenses are constructed using an elastomeric polymer chamber filled with a high-index liquid. In this work, we investigate the effect of elastomeric creep on the deformation and eventual degradation of these tunable lenses. We use numerical analysis of a deformable circular disk representative of the lens and provide rigorous experimental results testing the creep property of a number of elastomers. Finally, we provide a comparative study of different elastomeric materials and select the best one for this application.

Batch-Fabricated α-Si Assisted Nanogap Tunneling Junctions.

This paper details the design, fabrication, and characterization of highly uniform batch-fabricated sidewall etched vertical nanogap tunneling junctions for bio-sensing applications. The device consists of two vertically stacked gold electrodes separated by a partially etched sacrificial spacer layer of sputtered α-Si and Atomic Layer Deposited (ALD) SiO2. A ~10 nm wide air-gap is formed along the sidewall by a controlled dry etch of the spacer. The thickness of the spacer layer can be tuned by adjusting the number of ALD cycles. The rigorous statistical characterization of the ultra-thin spacer films has also been performed. We fabricated nanogap electrodes under two design layouts with different overlap areas and spacer gaps, from ~4.0 nm to ~9.0 nm. Optical measurements reported an average non-uniformity of 0.46 nm (~8%) and 0.56 nm (~30%) in SiO2 and α-Si film thickness respectively. Direct tunneling and Fowler-Nordheim tunneling measurements were done and the barrier potential of the spacer stack was determined to be ~3.5 eV. I-V measurements showed a maximum resistance of 46 × 103 GΩ and the average dielectric breakdown field of the spacer stack was experimentally determined to be ~11 MV/cm.

A Low-Profile Digital Eye-Tracking Oculometer for Smart Eyeglasses.

Wearable eye tracking devices have broad uses in medicine, psychology, augmented & virtual reality and consumer market research. Most mobile eye trackers available today utilize infrared imaging of the pupil and corneal reflections with video cameras. This tracking method requires sophisticated real-time processing of video signals consuming substantial electrical power. This method is thus unsuitable for light weight wearables such as adaptive smart eyeglasses for correction of presbyopia. In this paper we present a low-profile, low-power (7.7 mJ/sample) digital eye tracker oculometer based on infrared sclera tracking. The system is implemented using eight, 24-bit infrared proximity sensors and synchronous infrared LEDs. The pupil location is determined from 32 reflected pulsed light measurements independent of ambient illumination. The digital oculometer is 3.1 mm thick and weighs ~3 g. The tracker mounts adjacent to the tunable lenses in the smart eyeglasses frame. The eye tracker showed a pointing error of 1.3 degrees rms over a vertical and horizontal range of 30 degrees when tested by an observer.