Correction: Current and promising applications of Hf(IV)-based MOFs in cancer therapy.

Correction for 'Current and promising applications of Hf(IV)-based MOFs in cancer therapy' by Xuelin Chen et al., J. Mater. Chem. B, 2023, 11, 5693-5714, https://doi.org/10.1039/D3TB00267E.

Current and promising applications of Hf(IV)-based MOFs in clinical cancer therapy.

Cancer is one of the greatest challenges in medical science today as it poses a serious threat to human life. In view of this, myriad of therapeutic strategies are being developed for the treatment of cancer. Despite the use of various therapeutic approaches, they are still insufficient for the treatment of cancer. The rapid advancement of nanotechnology currently offers exciting possibilities for the creation of novel cancer therapy approaches. Metal organic frameworks (MOFs) are emerging multifunctional nanomaterials that find prospective applications in the biomedical field owing to their porosity, large specific surface area, and diversified structures. Amongst varied categories of MOFs, Hf(IV)-based MOFs that have been developed since 2012 and currently have been finding new applications and hence this class of MOFs are gaining immense attention amongst the material and biomaterial chemists. Most importantly, Hf(IV)-MOFs comprising high Z-Hf metal content may be capable of offering new therapeutic options for cancer therapy, nonlinear optics, as fluorescent sensors, and photoresponsive devices. In this review, the progress in Hf(IV)-based MOFs for the treatment of cancer using radiotherapy, chemotherapy, immunotherapy, phototherapeutic techniques, or a combination of two or more of these techniques have been explored. This review also provides insight regarding the current limitations and future prospects of Hf(IV)-MOFs for cancer therapy.

Current status and prospects of metal-organic frameworks for bone therapy and bone repair.

With the development of society, traumatic bone defects caused by accidents, diseases and surgeries have become common, eventually resulting in an increase in bone defects. The treatment of bone defects is characterized by a long period of treatment, high cost and uncontrollable outcomes. Also, it results in complications such as infection and bone discontinuity. Hence, due to this situation, the physical, mental and financial aspects of the patient are severely affected. What's more, such outcomes pose a challenge to orthopaedic surgeons. As a result, bone therapy and bone repair have become a hot topic of interest. In repairing bone defects, materials other than autogenous bone are still unable to provide good biocompatibility, osteogenesis, osteoconductivity and osteoinduction properties at the same time. In addition, the scarcity of autologous bone sources has forced the search for new autologous bone replacement materials. Metal organic frameworks (MOFs) are a new class of developed functional materials that have been widely used in the biomedical field during the recent years due to their porous nature, large specific surface area and diverse structures. With the progress in the investigation into bone treatment and repair, more and more investigators are using MOFs in bone therapy and bone repair. With these viewpoints, in the present perspective, the use of MOFs in bone therapy and bone repair has been summarized, and an insight into the future of MOFs in bone therapy and bone repair has been provided.