1.
Chem Commun (Camb)
; 50(93): 14554-7, 2014 Dec 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25308914
RESUMO
A novel one-pot strategy for the synthesis of 3-trifluoromethylquinoxalines from N-aryl enamines and nitromethane was developed. The tandem reaction is achieved through nitrosation of alkenes, tautomerization and cyclization, which can be applicable to a wide range of enamines with excellent functional group tolerance and afford quinoxalines in moderate to good yields.