Muscle torque in total knee arthroplasty: comparison of subvastus and midvastus approaches.

The subvastus and midvastus approaches are two of the most commonly performed quadriceps preserving approaches for total knee arthroplasty (TKA), which can hasten functional recovery and rehabilitation. However, there has not been sufficient investigation with respect to a quantitative comparison between the two approaches in terms of muscle strength. To compare outcomes with respect to muscle strength between these two approaches, quadriceps and hamstring muscle torques of 20 patients who underwent primary TKA with the subvastus (SV) approach and 10 patients who received the midvastus (MV) approach were measured after surgery. The median age of patients in the SV group (68 years, range 53-77 years) was significantly different that the median age of patients in the MV group (61 years, range 50-73 years) (P = 0.0141). There was no significant difference in patient weight, height, or postoperative duration before muscle testing between the SV and MV groups. There were no significant differences in peak muscle torque or hamstring/quadriceps (H/Q) ratio between the groups. We thus conclude peak muscle torque and H/Q ratios were not statistically different with the SV or MV approach, therefore functional outcome is comparable.

Effects of anterolateral minimally invasive surgery in total hip arthroplasty on hip muscle strength, walking speed, and functional score.

We conducted this study to observe the difference in muscle strength and walking speed between patients who underwent total hip arthroplasty (THA) in whom an anterolateral mini-incision technique was used and those in whom a conventional approach was used. Fifty-three patients who underwent a mini-incision THA were matched by diagnosis, sex, age, period elapsed since surgery (which ranged from 6 months to 4 years), weight, and height to 53 patients who underwent THA using the conventional anterolateral approach. During the first year after surgery, patients with the mini-incision THA had significantly better hip muscle strength, walking speed, and functional score (P < .05). At 1 year, the performance characteristics studied were statistically equivalent (P > .05). Although the mini-incision technique is more difficult than the conventional technique, its use by experienced surgeons can produce quicker short-term recovery.

Estimated risk score for spine fracture in the specific bending activity of normal Taiwanese men and women.

OBJECTIVE: To investigate the effects of biologic age, as well as chronologic age, on the vertebral ultimate load (strength) and risk score of vertebral fracture (Phi) between the genders. SUMMARY OF BACKGROUND DATA: Previous studies have shown a good correlation between the biomechanical strength of vertebral bodies and measured bone mineral parameters, whereas other factors also contribute to the bone strength and risk of fractures. Combining multiple factors into a single assessment may provide more comprehensive and individualized estimations of the fracture risk. In this study, we applied the measured bone mineral content (BMC) and bone projection area of the second through the fourth lumbar vertebrae (L2-L4) to assess the biomechanical strength of lumbar vertebrae. In addition, we used the body segment model to estimate the load of the L3 vertebral body during a bending-forward activity, to then estimate the risk score (Phi) of vertebral compression fracture in healthy Chinese volunteers in Taiwan, and to analyze the effects of gender and age on the risk score (Phi). METHODS: A total of 611 females and 235 males aged 22-80 years were included in this study. The anteroposterior BMC and projection area of lumbar spine were measured by a Norland XR-26 dual energy radiograph absorptiometer (Norland Corp., Ft. Atkinson, WI). The estimated ultimate strength (L) of lumbar spine was calculated from the regression equation using anteroposterior lumbar BMC and bone area according to Bassman et al (Paper presented at: 39th Annual Meeting of Orthopedic Research Society; February 1993; San Francisco, CA). The estimated spinal load (F) for a person bending over with back horizontal, either with hand free (F0), lifting a 20 kg weight (F20), or a 30 kg weight (F30), was calculated from a force diagram according to William and Lissner. Risk score (Phi) was defined as the quotient of F/L. RESULTS: The results showed an age-related decrease of bone mineral density (P < 0.001) in both genders corrected for weight and height. Using the multiple linear regression analysis and analysis of covariance, Phi for F0, F20, and F30 increased significantly, with increasing age only in females (P < 0.0001), especially after menopause, but not in males. The Phi of postmenopausal females was significantly larger than those of younger females (i.e., F0 (Phi) 0.533 +/- 0.075 vs. 0.458 +/- 0.064, P < 0.001; F20 (Phi) 0.903 +/- 0.101 vs. 0.789 +/- 0.080, P < 0.001; and F30 (Phi) 1.087 +/- 0.117 vs. 0.954 +/- 0.090, respectively, P < 0.001). In females, the ultimate load of the spine and Phi began to decrease to a significant level since the fifth decade, whereas in the males, the similar trends occurred since the sixth decade. Comparing both genders, the F0 (Phi) was slightly yet significantly larger in the young males (< 50 years) than the premenopausal females with similar ages (P < 0.001), but older females had higher F0 (Phi) values than males older than 60 years. Moreover, the Phi increased more prominently in the postmenopausal females with the weight lifted. As a result, both F20 (Phi) and F30 (Phi) were significantly larger in females older than 50 years as compared to males with the similar ages (P < 0.001). CONCLUSIONS: Our findings emphasize the importance of Phi, which considers BMC, bone size, body weight, body height, and weight lifted, for evaluating a more individualized risk of spine fracture in elderly men and postmenopausal women. The Phi increased more prominently with lifting weight and increased with aging only in the early postmenopausal females. The study showed that a combination of bone mass and anthropometric parameters provides a more individualized assessment of fracture risk than bone mineral density alone.

Effects of a home program on strength, walking speed, and function after total hip replacement.

OBJECTIVE: To assess the efficacy of a home exercise program in increasing hip muscle strength, walking speed, and function in patients more than 1.5 years after total hip replacement (THR). DESIGN: Randomized controlled trial. SETTING: Kinesiology laboratory. PARTICIPANTS: Fifty-three patients with unilateral THR were randomly assigned to the training (n=26) and control (n=27) groups. Patients in the training group were further divided into exercise-high (n=13) and exercise-low (n=13) compliance groups according to their practice ratio (high, > or =50%). INTERVENTION: The training group underwent a 12-week home program that included hip flexion range of motion exercises for both hip joints; strengthening exercises for bilateral hip flexors, extensors, and abductors; and a 30-minute walk every day. The control group did not receive any training. MAIN OUTCOME MEASURES: Strength of bilateral hip muscles, free and fast walking speeds while walking over 3 different terrains, and functional performance were assessed by using a dynamometer, videotape analysis, and the functional activity part of the Harris Hip Score, respectively, before and after the 12-week period. RESULTS: Subjects in the exercise-high compliance group showed significantly (P <.05) greater improvement in muscle strength for the operated hip, fast walking speed, and functional score than those in the exercise-low compliance and control groups. CONCLUSIONS: The designed home program was effective in improving hip muscle strength, walking speed, and function in patients after THR who practiced the program at least 3 times a week, but adherence to this home program may be a problem.

The role of titanium in the altered endotoxin-induced nitric oxide synthase expression in alveolar macrophages from titanium-alloy-implanted rats.

We have found that the concentration of titanium (Ti) in the blood of patients with loosened Ti-alloy prostheses is elevated. An increase in the levels of elemental Ti in the blood and lung tissues of rats with an alloyed-Ti implant also has been found. The cellular reaction to elevated elemental Ti in the circulation remains unclear. We further performed experiments to examine the changes of inducible nitric oxide synthase (iNOS) expression in alveolar macrophages from alloyed-Ti-implanted rats. The elevation of nitrite and iNOS expression induced by lipopolysaccharide (LPS) was suppressed. The in vitro effect of a soluble form of Ti was further investigated. Ti (0.01-0.06 mM) inhibited the LPS-induced nitrite production and iNOS expression in alveolar macrophages from normal rats without any cytotoxic effects. LPS induced protein tyrosine phosphorylation, tyrosine-phosphorylation of lyn (a CD14-receptor-associated-tyrosine kinase), and degradation of IkappaB-alpha protein (inhibitor of NF-kappaB) in alveolar macrophages. These events were inhibited by co-incubation with Ti. These results indicate that elemental Ti may impair iNOS expression in alveolar macrophages through the alteration of protein tyrosine phosphorylation and NF-kappaB activation. The inhibitory action of Ti on cellular responses of alveolar macrophages may be anti-inflammatory and thus may depress local defense mechanisms related to microbial killing.

Muscle torques in total knee arthroplasty with subvastus and parapatellar approaches.

The current study was designed to compare muscle torques when using the subvastus and parapatellar approaches for unilateral total knee arthroplasty. Twelve female patients had unilateral total knee arthroplasty with the subvastus approach from January 1997 to June 1998. The historic control group consisted of 16 female patients who had unilateral total knee arthroplasty with the parapatellar approach from July 1994 to January 1997. Six and 12 months after surgery, a Cybex dynamometer was used to measure isometric and isokinetic muscle strength. Two parameters were used to compare the two approaches, the first parameter was the difference in peak torque between the surgically treated knee and the baseline value for the healthy knee, and the second parameter was the hamstring to quadriceps peak-torque ratio, again using the value for the healthy knee as baseline. The subvastus approach resulted in an initial higher peak torque in the quadriceps 6 months after surgery, but this difference became insignificant 12 months postoperative. Using the subvastus approach, the hamstring to quadriceps peak-torque ratio reached the normal range (0.50-0.80) sooner than was the case using the parapatellar approach. There is a phenomenon of cross adaptation of the untreated knee to the surgically treated knee, and knees operated on by the subvastus approach showed functional recovery at an earlier date than those operated on by the parapatellar approach.