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1.
Br J Psychol ; 2024 Jul 23.
Artigo em Inglês | MEDLINE | ID: mdl-39041068

RESUMO

Collaboration has an essential role in memory, and how to appropriately use it to affect individual memory positively is a matter of concern. The meta-analysis generally assessed the effect of collaboration on subsequent individual retrieval, registered on the PROSPERO platform and adhering to the PRISMA guidelines, using the Web of Science, Science Direct, CNKI and WanFang databases with post-collaborative memory as the main subject, screened studies published up to December 31, 2023, a total of 64 studies with 101 effect sizes, including 13,398 participants from 11 countries. Heterogeneity test, sensitivity analysis, subgroup analysis and meta-regression analysis were performed on the included studies, while publication bias was assessed. The results found that collaboration improves subsequent individual retrieval memory more than individuals, and collaboration has a moderate facilitating effect on subsequent individual retrieval. Group size, material category, category size, collaboration phase, collaboration approach, task process and test method were among the moderating variables. The study emphasizes the role of collaboration in cognition and demonstrates the post-collaborative benefits. The conclusions are of value for developing methods to improve individual memory.

2.
Behav Sci (Basel) ; 14(7)2024 Jul 04.
Artigo em Inglês | MEDLINE | ID: mdl-39062390

RESUMO

How to allocate study time is an important decision-making problem learners face. Research on this problem can help improve the learning performance of learners and provide guidance for teaching activities. This research aimed to explore the potential of anchors (prior information that may influence individual decision-making and judgment under uncertainty) as clues for study time allocation and examine the effectiveness of study time allocation under the influence of anchors. Sixty-two Chinese university students (Mage = 21.21, SD = 1.74; 44 females) studied 20 word pairs under self-paced learning instructions. These instructions either set a high anchor (i.e., the typical participant spent 15 s learning each pair) or a low anchor (i.e., the typical participant spent 5 s learning each pair) for study time. After a brief distraction phase, participants took a cued recall test. The results showed that the higher the anchor value, the longer the corresponding study time, and the longer the study time, the better the memory performance. These results reveal that there is both an anchoring effect and a labor-and-gain effect in self-paced study time allocation. This study extends the range of observable anchoring effects and provides important information on allocating study time effectively.

3.
Environ Sci Pollut Res Int ; 31(32): 44730-44743, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38954343

RESUMO

Owing to the impact of the effluent C/N from the secondary structures of urban domestic wastewater treatment plants, the denitrification efficiency in constructed wetlands (CWs) is not satisfactory, limiting their widespread application in the deep treatment of urban domestic wastewater. To address this issue, we constructed enhanced CWs and conducted orthogonal experiments to investigate the effects of different factors (C/N, fillers, and plants) on the removal of conventional pollutants and the reduction of greenhouse gas (GHG) emission. The experimental results indicated that a C/N of 8, manganese sand, and calamus achieved the best denitrification efficiencies with removal efficiencies of 85.7%, 95.9%, and 88.6% for TN, NH4+-N, and COD, respectively. In terms of GHG emission reduction, this combination resulted in the lowest global warming potential (176.8 mg/m2·day), with N2O and CH4 emissions of 0.53 and 1.25 mg/m2·day, respectively. Characterization of the fillers revealed the formation of small spherical clusters of phosphates on the surfaces of manganese sand and pyrite and iron oxide crystals on the surface of pyrite. Additionally, the surface Mn (II) content of the manganese sand increased by 8.8%, and the Fe (III)/Fe (II) and SO42-/S2- on pyrite increased by 2.05 and 0.26, respectively, compared to pre-experiment levels. High-throughput sequencing indicated the presence of abundant autotrophic denitrifying bacteria (Sulfuriferula, Sulfuritalea, and Thiobacillus) in the CWs, which explains denitrification performance of the enhanced CWs. This study aimed to explore the mechanism of efficient denitrification and GHG emission reduction in the enhanced CWs, providing theoretical guidance for the deep treatment of urban domestic wastewater.


Assuntos
Gases de Efeito Estufa , Águas Residuárias , Áreas Alagadas , Águas Residuárias/química , Eliminação de Resíduos Líquidos/métodos , Desnitrificação
4.
J Ethnopharmacol ; 335: 118599, 2024 Jul 21.
Artigo em Inglês | MEDLINE | ID: mdl-39043352

RESUMO

ETHNOPHARMACOLOGICAL RELEVANCE: Shenlin Baizhu Decoction (SLBZD), which comes from 'Taiping Huimin Heji Ju Fang', belongs to a classical prescription for treating spleen deficiency and dampness obstruction (SQDDS)-type ulcerative colitis (UC) in traditional Chinese medicine. However, the mechanism of SLBZD in treating UC with SQDDS remains unclear. AIM OF THE STUDY: This study aims to investigate the mechanism of SLBZD against SQDDS-type UC of based on the "gut microbiota and metabolism - bone marrow" axis to induce endogenous bone marrow mesenchymal stem cells (BMSCs) homing. MATERIALS AND METHODS: Ultra-performance liquid chromatography-mass spectrometry was used to analysis of SLBZD qualitatively. The efficacy of SLBZD in SQDDS-type UC was evaluated based on the following indicators: the body weight, colon length, disease activity index (DAI) score, Haemotoxylin and Eosin (H&E) pathological sections, and intestinal permeability proteins (occluding and ZO-1). 16S rRNA gene sequencing and non-target metabolomics were performed to identify gut microbiota changes and its metabolites in feces, respectively. BMSCs in each group was collected, cultured, and analyzed. Optimal passaged BMSCs were injected by tail vein into UC rats of SQDDS types. BMSCs homing to the colonic mucosal tissue was observed by immunofluorescent. Finally, the repairing effect of BMSCs homing to the colonic mucosal tissue after SLBZD treatment was analyzed by transmission electron microscopy, qRT-PCR, and immunohistochemistry. RESULTS: SLBZD effectively improved the colonic length and the body weight, reduced DAI and H&E scores, and increased the expression of the intestinal permeability proteins, including occluding and ZO-1, to treat SQDDS-type UC. After SLBZD treatment, the α-diversity and ß-diversity of the gut microbiota were improved. The differential microbiota was screened as Aeromonadaceae, Lactobacillaceae, and Clostridiaceae at the family level, and Aeromonas, Lactobacillus, Clostridium_sensu_stricto_1 at the genus level. Meanwhile, the main metabolic pathway was the galactose metabolism pathway. SLBZD treatment timely corrected the aberrant levels of ß-galactose in peripheral blood and bone marrow, senescence-associate-ß-galactosidase in BMSCs, and galactose kinase-2, galactose mutase, and galactosidase beta-1 in peripheral blood to further elevate the expression levels of senescence-associated (SA) proteins (p16, p53, p21, and p27) in BMSCs. The Spearman's correlation analysis demonstrated the relationship between microbiota and metabolism, and the relationship between the galactose metabolism pathway and SA proteins. After BMSCs in each group injection via the tail vein, the pharmacodynamic effects were consistent with those of SLBZD in SQDDS-type UC rats. Furthermore, BMSCs have been homing to colonic mucosal tissue. BMSCs from the SLBZD treatment group had stronger restorative effects on intestinal permeability function due to increasing protein and mRNA expressions of occludin and ZO-1, and decreasing the proteins and mRNA expressions of SDF-1 and CXCR4 in colon. CONCLUSIONS: SLBZD alleviated the damaged structure of gut microbiota and regulated their metabolism, specifically the galactose metabolism, to treat UC of SDDOS types. SLBZD treatment promotes endogenous BMSCs homing to colonic mucosal tissue to repaire the intestinal permeability. The current exploration revealed an underlying mechanism wherein SLBZD activates endogenous BMSCs by targeting 'the gut microbiota and its metabolism-bone marrow' axis and repairs colonic mucosal damage to treat SDDOS-type UC.

5.
Front Psychol ; 15: 1361878, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38694438

RESUMO

This paper explored the training methods to improve the level of deaf college students' ToM. Eighty deaf college students were selected as participants and randomly divided into experimental group and control group. The ToM training group received ToM training; The non-ToM training group received physical-conversation training. Cognitive ToM task and affective ToM task were used to investigate the training effect. After training, the level of ToM of deaf college students who received ToM training was significantly improved. The results show that ToM training can effectively promote the level of deaf college students' ToM.

6.
Front Cell Infect Microbiol ; 14: 1258246, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38362497

RESUMO

Pulmonary fibrosis (PF) is a terminal change of a lung disease that is marked by damage to alveolar epithelial cells, abnormal proliferative transformation of fibroblasts, excessive deposition of extracellular matrix (ECM), and concomitant inflammatory damage. Its characteristics include short median survival, high mortality rate, and limited treatment effectiveness. More in-depth studies on the mechanisms of PF are needed to provide better treatment options. The idea of the gut-lung axis has emerged as a result of comprehensive investigations into the microbiome, metabolome, and immune system. This theory is based on the material basis of microorganisms and their metabolites, while the gut-lung circulatory system and the shared mucosal immune system act as the connectors that facilitate the interplay between the gastrointestinal and respiratory systems. The emergence of a new view of the gut-lung axis is complementary and cross-cutting to the study of the mechanisms involved in PF and provides new ideas for its treatment. This article reviews the mechanisms involved in PF, the gut-lung axis theory, and the correlation between the two. Exploring the gut-lung axis mechanism and treatments related to PF from the perspectives of microorganisms, microbial metabolites, and the immune system. The study of the gut-lung axis and PF is still in its early stages. This review systematically summarizes the mechanisms of PF related to the gut-lung axis, providing ideas for subsequent research and treatment of related mechanisms.


Assuntos
Fibrose Pulmonar , Humanos , Células Epiteliais Alveolares , Matriz Extracelular , Fibroblastos , Metaboloma , Pulmão
7.
BMC Cardiovasc Disord ; 24(1): 118, 2024 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-38378465

RESUMO

OBJECTIVE: To assess the efficacy of ibutilide administration during radiofrequency catheter ablation of persistent atrial fibrillation (AF), to explore the success rate of conversion and related influential factors, and to analyze the effects of ibutilide on postoperative recurrence. METHODS: A total of 192 patients with persistent AF who underwent catheter ablation from January 1, 2019, to December 31, 2021. These patients failed in conversion of AF to normal sinus rhythm by intraoperative catheter ablation. Patients were categorized into effective group (115 cases) and ineffective group (77 cases) based on whether sinus rhythm was restored after application of ibutilide. RESULTS: The overall success rate of conversion using ibutilide administration was 59.9%. The success rate was associated with weight ((68.12 ± 11.72 vs. 72.83 ± 12.08) kg, P = 0.008), the duration of AF ((34.67 ± 55.68 vs. 66.52 ± 95.21) months, p = 0.008), diameter of left atrium (LAD) ((44.39 ± 5.80 vs. 47.36 ± 6.10) mm,P = 0.002), and N-terminal pro-brain natriuretic peptide (NT-proBNP) level ((854.85 ± 770.84 vs. 662.88 ± 659.18) pg/ml,P = 0.030). The results showed the duration of AF was associated with early recurrence, while early recurrence was not a risk factor for late recurrence. And duration of AF was associated with postoperative maintenance time of normal sinus rhythm, whereas successful conversion into normal sinus rhythm using ibutilide administration had no influence on postoperative maintenance time of normal sinus rhythm. CONCLUSION: Ibutilide showed to be effective in catheter ablation of AF, the success rate of conversion was correlated with the duration of AF, LA diameter, and NT-proBNP level. Besides, the duration of AF was found as a risk factor for early postoperative recurrence, while ibutilide administration for successful conversion had no influence on predicting postoperative recurrence and had no influence on postoperative maintenance time of sinus rhythm.


Assuntos
Fibrilação Atrial , Ablação por Cateter , Sulfonamidas , Humanos , Fibrilação Atrial/diagnóstico , Fibrilação Atrial/tratamento farmacológico , Fibrilação Atrial/cirurgia , Resultado do Tratamento , Átrios do Coração , Ablação por Cateter/efeitos adversos , Ablação por Cateter/métodos , Recidiva
8.
Int Heart J ; 65(1): 159-164, 2024 Jan 31.
Artigo em Inglês | MEDLINE | ID: mdl-38148007

RESUMO

This study present a case of a 49-year-old woman who suffered from resistant hypertension, hypokalemia, hypomenorrhea, and infertility. She was hospitalized 6 years earlier for hypomenorrhea and abdominal pain at the Xiamen Maternity and Child Health Hospital, where she was diagnosed with Asherman syndrome. During hospitalization, a computed tomography examination revealed an adrenal mass. She was referred to Xiamen University Affiliated Zhongshan Hospital for pheochromocytoma and underwent surgical resection of the left adrenal gland. The adrenal cortex adenoma was confirmed by pathological biopsy. Six years later, the patient also presented with hypertension and hypokalemia to our emergency department. A diagnosis of 17α-hydroxylase deficiency was established through the analysis of clinical and laboratory characteristics. The genetic analysis of CYP17A1 revealed compound heterozygous mutations, 1 of which was a mutation of c.1226 C>G, and the other c.297+2T>C.


Assuntos
Neoplasias das Glândulas Suprarrenais , Hiperplasia Suprarrenal Congênita , Ginatresia , Hipertensão , Hipopotassemia , Feocromocitoma , Criança , Feminino , Humanos , Gravidez , Pessoa de Meia-Idade , Hiperplasia Suprarrenal Congênita/diagnóstico , Hiperplasia Suprarrenal Congênita/genética , Feocromocitoma/complicações , Feocromocitoma/diagnóstico , Feocromocitoma/genética , Mutação , Neoplasias das Glândulas Suprarrenais/complicações , Neoplasias das Glândulas Suprarrenais/diagnóstico , Neoplasias das Glândulas Suprarrenais/genética , Distúrbios Menstruais
9.
J Pediatr Orthop ; 43(6): 355-361, 2023 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-36914266

RESUMO

BACKGROUND: Cubitus varus deformity is a complex 3-dimensional deformity. Various osteotomies have been introduced to correct this deformity, however, there is no consensus on the best procedure to correct the deformity while avoiding complications. In this retrospective study, we used a modified inverse right-angled triangle osteotomy to treat 22 children with posttraumatic cubitus varus deformity. The primary objective was to evaluate this technique by presenting its clinical and radiologic results. METHODS: Twenty-two consecutive patients with a cubitus varus deformity underwent a modified reverse right-angled triangle osteotomy between October 2017 and May 2020 and were then followed for a minimum of 24 months. We evaluated its clinical and radiologic results. Functional outcomes were assessed using Oppenheim criteria. RESULTS: The average follow-up period was 34.6 months (range, 24.0 to 58.1 months). The mean range of motion was 4.32 degrees (range, 0 degrees to 15 degrees)/122.73 degrees (range, 115 degrees to 130 degrees) (hyperextension/flexion) before surgery and 2.05 degrees (range, 0 degrees to 10 degrees)/127.27 degrees (range, 120 degrees to 145 degrees) at the final follow-up. There were significant ( P < 0.05) differences between the flexion and hyperextension angles before surgery and at the final follow-up. Based on Oppenheim criteria, results were excellent for 20, good for 2, and none of the patients had poor results. The mean humerus-elbow-wrist angle improved from 18.23 degrees (range, 10 degrees to 25 degrees) varus preoperatively to 8.45 degrees (range, 5 degrees to 15 degrees) valgus postoperatively ( P < 0.05). The mean of the preoperative lateral condylar prominence index was 3.52 (range, 2.5 to 5.2) and the average postoperative lateral condylar prominence index was -3.28 (range, -1.3 to -6.0). All patients were pleased with the overall appearance of their elbows. CONCLUSIONS: The modified reverse right-angled triangle osteotomy can precisely and stably correct the deformity in the coronal and sagittal planes, we recommend this technique as a simple, safe, and reliable correction of cubitus varus deformity. LEVEL OF EVIDENCE: Level IV; case series; therapeutic studies-investigating the results of treatment.


Assuntos
Articulação do Cotovelo , Fraturas do Úmero , Deformidades Articulares Adquiridas , Deformidades Congênitas dos Membros , Humanos , Criança , Cotovelo , Fraturas do Úmero/complicações , Fraturas do Úmero/diagnóstico por imagem , Fraturas do Úmero/cirurgia , Resultado do Tratamento , Estudos Retrospectivos , Deformidades Articulares Adquiridas/etiologia , Deformidades Articulares Adquiridas/cirurgia , Osteotomia/métodos , Articulação do Cotovelo/cirurgia , Deformidades Congênitas dos Membros/complicações , Amplitude de Movimento Articular
10.
Memory ; 31(3): 406-420, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-36651520

RESUMO

We experimentally explored whether and how conversation dynamics would benefit collaborative remembering in intimate couples over time. To this end, we ran a study with a three-factor mixed design with relationship type (couples vs. strangers) and age (older adults vs. younger adults) as between-participants variables, and remembering condition (collaborative vs. individual) as a within-participants variable. Thirty pairs of intimate couples (fifteen long-term relationship older couples, fifteen short-term relationship younger couples) and thirty pairs of corresponding stranger-pairs (including older strangers and younger strangers) were compared with respect to recall accuracy and conversation dynamics, specifically considering the role of gender. Results revealed significant collaborative facilitation only in older couples. Also, females' communication behaviours facilitated males' collaborative remembering performance only in older (vs. younger) couples. In addition, a gender-specific pattern of shifts from the individual to collaborative context emerged only in older couple (vs. strangers). The findings are consistent with the notion that a longer experience of collaboration and more effective conversation dynamics allow older (vs. younger) couples to perform better at collaborative remembering. We discuss processes underlying the observed gender differences, and the social and motivational implications of collaborative remembering.


Assuntos
Comportamento Cooperativo , Rememoração Mental , Masculino , Feminino , Humanos , Idoso , Comunicação , Fatores Sexuais , Parceiros Sexuais
11.
ACS Appl Mater Interfaces ; 15(2): 2843-2851, 2023 Jan 18.
Artigo em Inglês | MEDLINE | ID: mdl-36594711

RESUMO

Nickel-based hydroxides and their derivatives exhibit relatively low capacities and unsatisfactory durability as cathode materials for rechargeable alkaline batteries. In this work, a hybrid NiCo-B nanosheet cathode, integrating electrolyte ion-shuttling channels and electron-transferring networks into a metal-organic framework (MOF), was devised delicately. In the structure, the hybrid ion/electron dual pathways were constructed by NiCo-MOF frameworks and NiCo-B interpenetration networks. It revealed that nano-phase electron-transferring pathways in the MOF obviously boosted ion intercalation kinetics. The as-obtained hybrid NiCo-B nanosheets as cathode materials exhibited reversible capacity as high as 280 mA h g-1 at a current density of 1 A g-1 and excellent rate capability with a capacity retention of 78% from 1 to 10 A g-1. After 2000 charge/discharge cycles at 4 A g-1, the capacity still remained at 94% of the initial one. A full battery assembled with a hybrid NiCo-B cathode and a Fe2O3 anode showed a high capacity of 250 mA h g-1 and a considerable stability of 89% after 1000 cycles. Ragone plots indicated the highest energy density of 409 W h kg-1 and the lowest power density of 1.5 kW kg-1, outperforming other aqueous batteries. It revealed that a syngenetic structure of ion/electron hybrid dual pathways integrated into an MOF could be a potential strategy to optimize ion intercalation electrode materials for alkaline batteries.

12.
Neurochem Res ; 48(5): 1361-1369, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-36454394

RESUMO

BACKGROUND: Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), regulated by AMPK, is an important regulator of mitochondrial fusion. At present, whether the AMPK/PGC-1α signaling pathway regulates mitochondrial dynamics in epileptic rats is still unknown. METHODS: Adult male Sprague-Dawley (SD) rats were randomly divided into fourgroups: the control group (0.9% saline, n = 5), the EP groups (lithium-pilocarpine was used to induce epilepsy, and tissues were harvested at 6 and 24 h, every time point, n = 5), the EP + Compound C group (the specific inhibitor of PGC-1α, 15 mg/kg in 2% DMSO, n = 5), and the EP + DMSO group (0.9% saline + 2% DMSO, n = 5). To investigate whether PGC-1α participates in seizures by regulating the expression of mitofusin1/2(MFN1/2)in rats. RESULTS: In this study, the behavioral results indicate that the seizure susceptibility of the rats to epilepsy was increased when the expression of PGC-1α was inhibited. Subsequently, Western blot results suggested that the expression level of both MFN1 and MFN2 in the hippocampus was higher at 6 and 24 h after an epileptic seizure. Besides, the expression of PGC-1α and MFN2 was significantly decreased in the hippocampus when the epileptic rats were treated with Compound C. Furthermore, the immunofluorescence analysis of the localization of MFN1/2 and PGC-1α showed that MFN1/2 was mainly expressed in neurons but not astrocytes in the hippocampus and cerebral cortex of rats. Meanwhile, PGC-1α colocalized with the excitatory post-synaptic marker PSD95, suggesting that PGC-1α may regulate the seizure susceptibility of the rats by mediating excitatory post-synaptic signaling. CONCLUSION: The AMPK/PGC-1α signaling pathway may play an important role in the lithium-pilocarpine-induced epileptic rat model by mediating the expression of fusion proteins.


Assuntos
Epilepsia , Dinâmica Mitocondrial , Ratos , Masculino , Animais , Ratos Sprague-Dawley , Proteínas Quinases Ativadas por AMP/metabolismo , Dimetil Sulfóxido , Lítio , Pilocarpina , Solução Salina , Convulsões/induzido quimicamente , Epilepsia/induzido quimicamente , Coativador 1-alfa do Receptor gama Ativado por Proliferador de Peroxissomo/metabolismo
14.
Clin Cardiol ; 45(12): 1229-1235, 2022 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-36124718

RESUMO

BACKGROUND: Cryoballoon ablation (CBA) is recommended for patients with symptomatic drug refractory paroxysmal atrial fibrillation (pAF). However, substantial atrial fibrillation (AF) recurrence is common during follow-up. Searching for a potential biomarker representing both myocardial injury and inflammation to identify patients at high risk of AF recurrence after CBA is very meaningful for postoperative management of AF patients. HYPOTHESIS: To evaluate the clinical efficacy of high-mobility group box 1 (HMGB1) protein released from the left atrium to predict AF recurrence in pAF patients after CBA at 1-year follow-up. METHODS: We included 72 pAF patients who underwent CBA. To determine the expression levels of HMGB1, left atrial blood samples were collected from the patients before CBA and after the procedure through the transseptal sheath. Patients were followed up for AF recurrence for 1 year. RESULTS: A total of 19 patients of the 72 experienced AF recurrence. The level of postoperative HMGB1 (HMGB1post) was higher in the AF recurrence group than in the AF non recurrence group (p = .03). However, no differences were noted in the levels of other biomarkers such as preoperative high-sensitivity C-reactive protein (hs-CRP), postoperativehs-CRP, and preoperative HMGB1 between the two groups. Multiple logistic regression analysis revealed that a higher level of serum HMGB1post was associated with AF recurrence (odds ratio: 5.29 [1.17-23.92], p = .04). Receiver operating characteristic analysis revealed that HMGB1post had a moderate predictive power for AF recurrence (area under the curve: 0.68; sensitivity: 72%; and specificity: 68%). The 1-year AF-free survival was significantly lower in patients with a high HMGB1post level than in those with a low HMGB1post level (hazard ratio: 3.81 [1.49-9.75], p = .005). CONCLUSION: In pAF patients who under went CBA, the level of HMGB1 after CBA was associated with AF recurrence and demonstrated a moderate predictive power. Thus, we offer a potential biomarker to identify pAF patients at high risk of AF recurrence.


Assuntos
Fibrilação Atrial , Ablação por Cateter , Criocirurgia , Proteína HMGB1 , Humanos , Fibrilação Atrial/diagnóstico , Fibrilação Atrial/cirurgia , Criocirurgia/efeitos adversos , Criocirurgia/métodos , Ablação por Cateter/efeitos adversos , Ablação por Cateter/métodos , Resultado do Tratamento , Biomarcadores
15.
Front Psychol ; 13: 990332, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36118429

RESUMO

The aim of this study was to examine the effect of cognitive information processing (CIP) and social cognitive career theory (SCCT) group counseling on high school students' career adaptability. The study involved 81 students from grade 10 and grade 11 in a Chinese public high school. Among the 81 participants, 27 were in the CIP group, 28 were in the SCCT group, while the rest were in the control group. All participants completed a pre-test, post-test, and tracking-test assessment of their career adaptability. Results indicated that the interventions were effective for the students with low career adaptability, the CIP group counseling improved the career concern after the intervention, whereas the SCCT group revealed a more robust effect on career adaptability after 3 months of the intervention. The practical implications of the study for career interventions are also discussed.

16.
Viruses ; 14(8)2022 07 26.
Artigo em Inglês | MEDLINE | ID: mdl-35893690

RESUMO

Influenza A virus (IAV) requires the host cellular machinery for many aspects of its life cycle. Knowledge of these host cell requirements not only reveals molecular pathways exploited by the virus or triggered by the immune system but also provides further targets for antiviral drug development. To uncover critical pathways and potential targets of influenza infection, we assembled a large amount of data from 8 RNA sequencing studies of IAV infection for integrative network analysis. Weighted gene co-expression network analysis (WGCNA) was performed to investigate modules and genes correlated with the time course of infection and/or multiplicity of infection (MOI). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed to explore the biological functions and pathways of the genes in 5 significant modules. Top hub genes were identified using the cytoHubba plugin in the protein interaction network. The correlation between expression levels of 7 top hub genes and time course or MOI was displayed and validated, including BCL2L13, PLSCR1, ARID5A, LMO2, NDRG4, HAP1, and CARD10. Dysregulated expression of these genes potently impacted the development of IAV infection through modulating IAV-related biological processes and pathways. This study provides further insights into the underlying molecular mechanisms and potential targets in IAV infection.


Assuntos
Vírus da Influenza A , Influenza Humana , Biologia Computacional , Perfilação da Expressão Gênica , Ontologia Genética , Redes Reguladoras de Genes , Humanos , Vírus da Influenza A/genética , Mapas de Interação de Proteínas/genética
17.
J Deaf Stud Deaf Educ ; 27(4): 423-433, 2022 09 15.
Artigo em Inglês | MEDLINE | ID: mdl-35797703

RESUMO

This paper explored training methods to improve the Theory of Mind levels of Chinese college students with hearing loss and investigated the transfer effect of training. Ninety Chinese college students with hearing loss were randomly divided into two groups: the ToM training group and the physical-conversation training group. The ToM training group received ToM training, and the physical-conversation training group as the control group received physical-conversation training. All the participants attended four separate 60-min lectures. The ToM Story Task and the False Belief Task were used to assess the training's effect, and the ToM animation task was adopted to investigate the transfer effect. Before training, the level of ToM of the two participant groups was similar. After training, the ToM level of Chinese college students with hearing loss who participated in ToM training was significantly higher than the students who underwent physical-conversation training. Moreover, the findings revealed that ToM training has long-term transfer effects. This study thus showed that ToM training can effectively improve the ToM level of Chinese college students with hearing loss.


Assuntos
Educação , Perda Auditiva , Estudantes , China , Comunicação , Educação/métodos , Humanos , Estudantes/psicologia , Estudantes/estatística & dados numéricos , Teoria da Mente , Universidades
18.
Bioresour Technol ; 351: 127008, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35306128

RESUMO

High-solids anaerobic digestion (HS-AD) of food waste frequently confronted the acidification and failure under high organic loading rates (OLRs). Results indicated powdered activated carbon (PAC) addition significantly enhanced methane production and process stability than granular activated carbon, and columnar activated carbon at higher OLRs via accelerating the propionate consumption. Potential direct interspecies electron transfer (DIET) partners, including various syntrophic oxidation bacteria and methanogens, were enriched with the activated carbon (AC) addition. Furthermore, DIET contribution to methane production was 35% by PAC, predicated by the modified Anaerobic Digestion Model No.1 (ADM1). This study deeply elucidated the DIET mechanism and offered the potential foundations for the selection and applications of AC-based materials in HS-AD of food waste.


Assuntos
Carvão Vegetal , Eliminação de Resíduos , Anaerobiose , Reatores Biológicos , Elétrons , Alimentos , Metano , Esgotos/microbiologia
19.
Front Psychol ; 13: 822788, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35273544

RESUMO

Previous studies have demonstrated that lying can undermine memory and that its memory-undermining effects could be modulated by the cognitive resources required to tell lies. We extended the investigation of the memory-undermining effect by using a daily life setting in which participants were highly involved in a mock shopping task. Participants were randomly assigned to truth-telling, denying or mixed lying conditions. After finishing the shopping task, participants were told that two people wanted to know about their shopping lists and would ask them some questions in an interview. During the interview, participants were asked whether each of ten items were on the shopping list, five of which were randomly selected from the shopping list, while the other five were not sold in the store. In answering the interview questions, the truth-telling group was asked to respond honestly, the denying group was asked to give denial responses, and the mixed lying group was asked to respond deceptively. Thus, the denying group told five lies and the mixed lying group told ten lies in the interview. The item memory test, source memory test and destination memory test were given in an orderly manner 48 h after the interview. We found that the mixed lying group, rather than the denying group, forgot the lies they told in the interview and mistakenly believed they had lied about something that they had not lied about. Moreover, the mixed lying group retained fewer memories about the person they responded to than the honest group. In addition, participants in the mixed lying group had more non-believed memories than those in the truth-telling group in both item and source memory tests. We conclude that more lies could result in more memory disruptions in daily life.

20.
Psychol Res ; 86(6): 1763-1773, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34988638

RESUMO

Research has demonstrated that deceptive responses can undermine item and source memories. However, previous studies have often randomly assigned participants to an honest or deception group and asked them to respond in specific ways in an interview, rather than providing them a choice of what response to give. Moreover, little attention has been given to destination memory in previous research. Using a daily life paradigm, we investigated the effects of deception on memory. After completing a mock shopping task, participants were told that someone would ask them questions about their shopping lists. The participants voluntarily chose to tell the truth or lie in the interview and were encouraged to respond as they would in their daily lives. An item memory test, source memory test and destination memory test were given 48 h after the interview. Source and destination memories but not item memories were impaired for participants who chose to lie. Specifically, liars forgot the things about which they lied and mistakenly believed that they lied about many things that they did not, and they also did not remember to whom they lied. We conclude that deception can disrupt memory in daily life.


Assuntos
Enganação , Rememoração Mental , Humanos
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