Numerical simulation of vortex dynamics in type-II superconductors in oscillating magnetic field using time-dependent Ginzburg-Landau equations.

Time-dependent Ginzburg-Landau equations were solved by the finite difference scheme for a superconducting sample in steady and oscillating magnetic fields for 3D geometry. The dynamic behaviour of penetrating and leaving magnetic vortices in superconductor with the oscillating magnetic field was simulated. Carrier concentration density and the average magnetization of the sample were studied as a function of the external oscillating magnetic field. Anomalies in carrier concentrations at certain magnetic field values were observed and discussed. It was also observed that the area swept by magnetization versus external magnetic field is magnetic oscillation frequency dependent, which increases with increasing frequencies. It was suggested that this effect may cause instability in the superconducting characteristics of the sample over a number of cycles. Calculated energy patterns showed consistency with vortex patterns in the steady magnetic field. Magnetic oscillations initiated oscillations in energy components, ripples in superconducting energy are subjected to the entrance and leaving of vortices, while instability observed in interaction energy is referred to vortex relaxation time.

Characterization of role of the toxR gene in the physiology and pathogenicity of Vibrio alginolyticus.

toxR, a conserved virulence-associated gene in vibrios, is identified in Vibrio alginolyticus ZJ51-O, a pathogenic strain isolated from diseased fish. To reveal the role of ToxR in the pathogenicity of V. alginolyticus, a deletion mutant was constructed by allelic exchange. The mutant showed the same level of growth in trypticase soy broth (TSB) and iron-limiting condition, as the wild type strain. However, deletion of toxR severely reduced resistance against bile salts and the capability of biofilm formation. Outer-membrane protein (OMP) analysis showed that a 37-kD protein was absent and a 43-kD protein was decreased in the mutant. By MS/MS, the two proteins are identified as the homologues of OmpT and OmpN, respectively. These data suggest that ToxR might have enhanced the bile resistance and biofilm formation through modulating the production of OMP without affecting the ability of iron acquisition and the virulence to the fish via injection. These results indicate that ToxR may assist V. alginolyticus to colonize on the surface of the fish intestine which is crucial for the initiation of the infection, though it may not be involved in the proliferation of the bacteria in the host tissue.