Leveraging network analysis to support experts in their analyses of subjects with MCI and AD.

In this paper, we propose a network analysis-based approach to help experts in their analyses of subjects with mild cognitive impairment (hereafter, MCI) and Alzheimer's disease (hereafter, AD) and to investigate the evolution of these subjects over time. The inputs of our approach are the electroencephalograms (hereafter, EEGs) of the patients to analyze, performed at a certain time and, again, 3 months later. Given an EEG of a subject, our approach constructs a network with nodes that represent the electrodes and edges that denote connections between electrodes. Then, it applies several network-based techniques allowing the investigation of subjects with MCI and AD and the analysis of their evolution over time. (i) A connection coefficient, supporting experts to distinguish patients with MCI from patients with AD; (ii) A conversion coefficient, supporting experts to verify if a subject with MCI is converting to AD; (iii) Some network motifs, i.e., network patterns very frequent in one kind of patient and absent, or very rare, in the other. Patients with AD, just by the very nature of their condition, cannot be forced to stay motionless while undergoing examinations for a long time. EEG is a non-invasive examination that can be easily done on them. Since AD and MCI, if prodromal to AD, are associated with a loss of cortical connections, the adoption of network analysis appears suitable to investigate the effects of the progression of the disease on EEG. This paper confirms the suitability of this idea Graphical Abstract Ability of our proposed model to distinguish a control subject from a patient with MCI and a patient with AD. Blue edges represent strong connections among the corresponding brain areas; red edges denote middle connections, whereas green edges indicate weak connections. In the control subject (at the top), most connections are blue. In the patient with MCI (at the middle), most connections are red and green. In the patient with AD (at the bottom), most connections are either absent or green. .

Building Topic-Driven Virtual IoTs in a Multiple IoTs Scenario.

In the last years, several attempts to combine the Internet of Things (IoT) and social networking have been made. In the meantime, things involved in IoT are becoming increasingly sophisticated and intelligent, showing a behavior that tends to look like the one of users in social networks. Therefore, it is not out of place to talk about profiles of things and about information and topics exchanged among them. In such a context, constructing topic-driven virtual communities starting from the real ones operating in a Multi-IoT scenario is an extremely challenging issue. This paper aims at providing some contributions in this setting. First of all, it presents the concept of profile of a thing. Then, it introduces the concept of topic-guided virtual IoT. Finally, it illustrates two approaches (one supervised and one unsupervised) to constructing topic-guided virtual IoTs in a Multi-IoT scenario.