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J Int Med Res ; 50(9): 3000605221123678, 2022 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-36171729

RESUMO

OBJECTIVES: Community-acquired pneumonia (CAP) is a global health condition that affects populations from all age groups. The laboratory identification of Mycoplasma pneumoniae as a causative agent of CAP is challenging because of its atypical and fastidious nature. Therefore, this study assessed the diagnostic potential of PneumoCLART bacteria® in identifying M. pneumoniae as a causative agent of pneumonia in hospitalized adults. METHODS: This prospective study used a cross-sectional approach to assess the diagnostic potential of PneumoCLART bacteria® for detecting M. pneumoniae in sputum samples procured from 27 patients with pneumonia who required hospitalization. RESULTS: The PneumoCLART bacteria® results illustrated that 7 of 27 patients with pneumonia were positive for M. pneumoniae (26%). However, the quality of sputum varied among the M. pneumoniae-positive and M. pneumoniae-negative samples. Fifty percent of the specimens obtained from patients positive for M. pneumoniae were saliva-contaminated and unsuitable for analysis. CONCLUSIONS: Because the leukocyte count was low and sputum specimens were saliva-contaminated, these findings require further validation to prove the utility of CLART® microarray technology for the identification of M. pneumoniae in pneumonia-positive patients. Conclusively, this prospective study included a small number of clinical samples, which likely affected its outcomes.


Assuntos
Infecções Comunitárias Adquiridas , Pneumonia por Mycoplasma , Pneumonia , Adulto , Bactérias , Infecções Comunitárias Adquiridas/diagnóstico , Humanos , Mycoplasma pneumoniae/genética , Pneumonia/diagnóstico , Pneumonia por Mycoplasma/diagnóstico , Estudos Prospectivos , Tecnologia
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