RESUMO
The main allergen responsible for contact dermatitis to nail polish is tosylamide-formaldehyde resin. The so-called hypoallergenic nail polishes are suposedly free of agents that commonly trigger reactions. The commercially available products and their compositions were studied. It was observed that most brands present at least one component capable of triggering the disease; therefore, allergic reaction may occur even when hypoallergenic polishes are used. There should be a proper investigation of the specific allergen through a patch test, because more than one component can cause an allergy, and we need to check the exact composition of each product.
Assuntos
Cosméticos/efeitos adversos , Cosméticos/química , Dermatite Alérgica de Contato/etiologia , HumanosRESUMO
Abstract The main allergen responsible for contact dermatitis to nail polish is tosylamide-formaldehyde resin. The so-called hypoallergenic nail polishes are suposedly free of agents that commonly trigger reactions. The commercially available products and their compositions were studied. It was observed that most brands present at least one component capable of triggering the disease; therefore, allergic reaction may occur even when hypoallergenic polishes are used. There should be a proper investigation of the specific allergen through a patch test, because more than one component can cause an allergy, and we need to check the exact composition of each product.
Assuntos
Humanos , Dermatite Alérgica de Contato/etiologia , Cosméticos/efeitos adversos , Cosméticos/químicaAssuntos
Humanos , Feminino , Adulto , Sarcoma de Kaposi/induzido quimicamente , Sarcoma de Kaposi/patologia , Neoplasias Cutâneas/induzido quimicamente , Neoplasias Cutâneas/patologia , Corticosteroides/efeitos adversos , Imuno-Histoquímica , Hanseníase Virchowiana/tratamento farmacológico , Herpesvirus Humano 8/isolamento & purificação , Doença IatrogênicaAssuntos
Corticosteroides/efeitos adversos , Sarcoma de Kaposi/induzido quimicamente , Sarcoma de Kaposi/patologia , Neoplasias Cutâneas/induzido quimicamente , Neoplasias Cutâneas/patologia , Adulto , Feminino , Herpesvirus Humano 8/isolamento & purificação , Humanos , Doença Iatrogênica , Imuno-Histoquímica , Hanseníase Virchowiana/tratamento farmacológicoRESUMO
A retrospective study was carried out between 2006-2011. Six hundred and eighteen patients with suspected allergic contact dermatitis underwent the standard patch test series recommended by the Brazilian Contact Dermatitis Research Group. The aim of our study was to evaluate the variation of positive patch-test results from standard series year by year. The most frequently positive allergens were: nickel sulfate, thimerosal and potassium bichromate. Decrease of positive patch-test results over the years was statistically significant for: lanolin (p=0.01), neomycin (p=0.01) and anthraquinone (p=0.04). A follow-up study should be useful in determining which allergens could be excluded from standard series, as they may represent low sensitization risk.