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1.
LGBT Health ; 10(5): 363-371, 2023 07.
Artigo em Inglês | MEDLINE | ID: mdl-36809196

RESUMO

Purpose: We compared the prevalence of depression, hazardous alcohol use, daily tobacco use, and hazardous alcohol and tobacco use (HATU) by sexual orientation and sex among Brazilian adults. Methods: Data were obtained from a national health survey conducted in 2019. This study included participants aged 18 years and older (N = 85,859). Adjusted prevalence ratios (APRs) and confidence intervals were estimated using Poisson regression models stratified by sex to examine the association between sexual orientation, depression, daily tobacco use, hazardous alcohol use, and HATU. Results: After controlling for the covariates, gay men showed a higher prevalence of depression, daily tobacco use, and HATU compared with heterosexual men (APR ranged from 1.71 to 1.92). Furthermore, bisexual men showed a higher prevalence (almost three times) of depression compared with heterosexual men. Lesbian women showed a higher prevalence of binge and heavy drinking, daily tobacco use, and HATU compared with heterosexual women (APR ranged from 2.55 to 4.44). Among bisexual women, the results were significant for all analyzed outcomes (APR ranged from 1.83 to 3.26). Conclusions: This study was the first to use a nationally representative survey to assess sexual orientation disparities related to depression and substance use by sex in Brazil. Our findings highlight the need for specific public policies aimed at the sexual minority population and for greater recognition and better management of these disorders by health professionals.


Assuntos
Minorias Sexuais e de Gênero , Transtornos Relacionados ao Uso de Substâncias , Adulto , Humanos , Feminino , Masculino , Brasil/epidemiologia , Depressão/epidemiologia , Comportamento Sexual , Heterossexualidade , Transtornos Relacionados ao Uso de Substâncias/epidemiologia , Inquéritos Epidemiológicos
3.
PLoS One ; 17(2): e0263385, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35130293

RESUMO

BACKGROUND: Increased physical activity levels and their determinations are essential issues worldwide. The Longitudinal Study of Physical Activity Determinants (ELDAF) aims to understand the roles of psychosocial and environmental factors in workers' physical activity levels. METHODS: A prospective cohort study of non-faculty civil servants from a public university (approximately 1,200 individuals) will start in 2022 (baseline). The primary measurements will be accelerometer- and questionnaire-based physical activity, social support, social network, socioeconomic status, bereavement, job stress, body image, common mental disorders, depression, and neighborhood satisfaction. Additional measurements will include necessary sociodemographic, physical morbidity, lifestyle and anthropometric information. Participants' places of residence will be geocoded using complete addresses. All participants will furnish written, informed consent before the beginning of the study. Pilot studies were performed to identify and correct potential problems in the data collection instruments and procedures. ELDAF will be the first cohort study conducted in Latin America to investigate physical activity and its determinants.


Assuntos
Emprego , Exercício Físico , Universidades/estatística & dados numéricos , Adulto , Imagem Corporal/psicologia , Brasil/epidemiologia , Estudos de Coortes , Comorbidade , Emprego/psicologia , Emprego/estatística & dados numéricos , Exercício Físico/psicologia , Exercício Físico/estatística & dados numéricos , Feminino , Humanos , Estilo de Vida , Estudos Longitudinais , Masculino , Transtornos Mentais/epidemiologia , Estresse Ocupacional/epidemiologia , Logradouros Públicos/estatística & dados numéricos , Classe Social , Fatores Socioeconômicos , Inquéritos e Questionários , Universidades/organização & administração
4.
Soc Psychiatry Psychiatr Epidemiol ; 57(7): 1491-1503, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-35044479

RESUMO

PURPOSE: Binge eating disorder (BED), bulimia nervosa (BN) and recurrent binge eating (RBE) are binge eating spectrum conditions causing a significant impact in individual's health and functioning. Information regarding those conditions came mostly from high-income countries. The objective of this study was to assess the prevalence of DSM-5 BED, BN and RBE and correlates in a representative sample from a metropolitan area of a middle-income country. METHODS: The data were obtained from a cross-sectional population-based household survey in two stages in Rio de Janeiro, Brazil. Noninstitutionalized residents aged 18-60 years were assessed by lay interviewers using the Questionnaire of Eating and Weight Patterns-5 (QEWP-5). Positive cases and a paired sample screen-negative cases were reassessed by phone with the Eating Disorders Section of SCID-I-P (adapted for DSM-5). The data were collected from September 2019 to February 2020. RESULTS: Overall, 2297 individuals were interviewed. Prevalence of BED was 1.4%, BN 0.7%, RBE 6.2%. Psychiatric comorbidities, such as depression, anxiety and ADHD were significantly more prevalent in people with BED, BN and RBE than in people without these eating problems. Several medical conditions, when controlling for body mass index, were significantly more prevalent in people with BED, BN and RBE. People with BED and BN had marked impairments in work/school, social and family life, reduced mental and physical HRQoL and under half had sought treatment. CONCLUSION: As in high income countries, in Rio de Janeiro, Brazil, BED, BN and RBE are prevalent conditions and are associated with elevated BMI, functional impairment, psychiatric and medical comorbidity and poorer HRQoL.


Assuntos
Transtorno da Compulsão Alimentar , Bulimia Nervosa , Bulimia , Transtornos da Alimentação e da Ingestão de Alimentos , Transtorno da Compulsão Alimentar/complicações , Transtorno da Compulsão Alimentar/diagnóstico , Transtorno da Compulsão Alimentar/epidemiologia , Brasil/epidemiologia , Bulimia/epidemiologia , Bulimia Nervosa/diagnóstico , Bulimia Nervosa/epidemiologia , Estudos Transversais , Transtornos da Alimentação e da Ingestão de Alimentos/complicações , Humanos
5.
Eur Geriatr Med ; 13(2): 407-413, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-35067908

RESUMO

PURPOSE: To evaluate the association between fear of falling (FoF) and spatial and temporal parameters of gait in older adults. METHODS: This cross-sectional study evaluated 291 clients of a private health care insurance who were over 65 years of age and living in the North Zone of Rio de Janeiro City in 2013. FoF was assessed by the Falls Efficacy Scale-International (FES-I-BR), and gait parameters, such as gait speed, cadence, step time, step length, stride length, and variability (standard deviation of stride length), were assessed using GAITRite®. The covariates were age, sex, history of falls, number of medications, cognitive decline, body mass index, and sight impairment. The association between FoF and gait parameters was assessed by linear regression, and the respective 95% confidence intervals (95% CIs) were calculated. RESULTS: The prevalence of FoF was 51.9%. The adjusted analyses showed an association between FoF and the following gait parameters: decreased gait speed, decreased cadence, increased step time, and decreased step and stride length. No association was found between FoF and stride lenght variability. CONCLUSION: This study suggests that FoF is associated with changes in gait parameters, with the exception of stride length variability. These findings show a need for interventions to reduce FoF in older adults, which is a modifiable factor that is related to gait changes. More studies are needed to elucidate the relationship between FoF and motor control of gait in older adults.


Assuntos
Medo , Marcha , Idoso , Brasil , Estudos Transversais , Humanos
6.
Rev Bras Med Trab ; 18(4): 472-487, 2021 Mar 03.
Artigo em Inglês | MEDLINE | ID: mdl-33688330

RESUMO

Knowledge of the psychosocial determinants of physical activity is critical to informing preventive and therapeutic interventions in the workplace. This study reviewed available evidence on psychosocial factors that have been associated with physical activity among workers. Studies were selected in December 2019 from the Scopus, Web of Science, and PubMed databases, with no date limits, using the following search terms: "physical activity", "physical exercise", "psychosocial", "workers", and "working-age". Thirty-nine studies published between 1991 and 2019 were evaluated. The determinants of physical activity investigated among workers were smoking status, stress, psychosocial working conditions, depression, anxiety, social relationships, work ability, job satisfaction, burnout, and self-efficacy. Some consistencies and controversies were observed in the associations among these determinants and physical activity and are discussed, as are suggestions for future studies. The findings of this review may be of interest to physical activity interventions designed to reduce psychosocial risks factors in work environments.

7.
Clinics (Sao Paulo) ; 75: e1814, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33263630

RESUMO

OBJECTIVES: To assess the prevalence of sarcopenic obesity and its association with functionality, lifestyle, biomarkers, and morbidities in older adults. METHODS: The study analyzed cross-sectional data from 270 older adults who participated in phase III of the Frailty in Brazilian Older People Study (Fragilidade em Idosos Brasileiros-Rio de Janeiro, FIBRA-RJ study-2013). They took part in a home interview surveying socioeconomic, demographic, lifestyle, morbidities, and functional data. Blood was collected for biochemical marker analysis and participants' body composition was determined by dual-energy X-ray absorptiometry. For women, the diagnosis of sarcopenic obesity was defined at a body fat percentage ≥38% and appendicular skeletal muscle mass index (ASMMI) <5.45 kg/m2. For men, a fat percentage ≥27% and ASMMI <7.26 kg/m2 was defined as sarcopenic obesity. Multivariate analysis was performed using a multinomial regression model (95% confidence intervals), with sarcopenic obesity as the outcome. RESULTS: The prevalence of sarcopenic obesity was 29.3%. In the final fitted model, the variables that displayed statistically significant association with sarcopenic obesity were lower gait speed, self-reported medical diagnosis of arthrosis or arthritis, and high levels of glycemia. CONCLUSION: The study showed a high prevalence of sarcopenic obesity in non-institutionalized older adults in Brazil. The finding that this condition was associated with modifiable risk factors may provide insights into measures directed at prevention and reduction of the risk of sarcopenic obesity in this population subgroup.


Assuntos
Fragilidade , Sarcopenia , Idoso , Idoso de 80 Anos ou mais , Biomarcadores , Composição Corporal , Brasil/epidemiologia , Estudos Transversais , Feminino , Fragilidade/epidemiologia , Humanos , Estilo de Vida , Masculino , Morbidade , Obesidade/complicações , Obesidade/epidemiologia , Prevalência , Sarcopenia/epidemiologia
8.
Clinics ; 75: e1814, 2020. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1142777

RESUMO

OBJECTIVES: To assess the prevalence of sarcopenic obesity and its association with functionality, lifestyle, biomarkers, and morbidities in older adults. METHODS: The study analyzed cross-sectional data from 270 older adults who participated in phase III of the Frailty in Brazilian Older People Study (Fragilidade em Idosos Brasileiros—Rio de Janeiro, FIBRA-RJ study-2013). They took part in a home interview surveying socioeconomic, demographic, lifestyle, morbidities, and functional data. Blood was collected for biochemical marker analysis and participants' body composition was determined by dual-energy X-ray absorptiometry. For women, the diagnosis of sarcopenic obesity was defined at a body fat percentage ≥38% and appendicular skeletal muscle mass index (ASMMI) <5.45 kg/m2. For men, a fat percentage ≥27% and ASMMI <7.26 kg/m2 was defined as sarcopenic obesity. Multivariate analysis was performed using a multinomial regression model (95% confidence intervals), with sarcopenic obesity as the outcome. RESULTS: The prevalence of sarcopenic obesity was 29.3%. In the final fitted model, the variables that displayed statistically significant association with sarcopenic obesity were lower gait speed, self-reported medical diagnosis of arthrosis or arthritis, and high levels of glycemia. CONCLUSION: The study showed a high prevalence of sarcopenic obesity in non-institutionalized older adults in Brazil. The finding that this condition was associated with modifiable risk factors may provide insights into measures directed at prevention and reduction of the risk of sarcopenic obesity in this population subgroup.


Assuntos
Humanos , Masculino , Feminino , Idoso , Idoso de 80 Anos ou mais , Sarcopenia/epidemiologia , Fragilidade/epidemiologia , Composição Corporal , Brasil/epidemiologia , Biomarcadores , Prevalência , Estudos Transversais , Morbidade , Estilo de Vida , Obesidade/complicações , Obesidade/epidemiologia
9.
PLoS One ; 14(1): e0211470, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30682158

RESUMO

PURPOSE: We investigated the stability, correlations and bidirectional relationship of light physical activities (PA), moderate and vigorous PA (MVPA), television viewing (TV) and video game/computer use (VG) in Brazilian adolescents. METHODS: Adolescent Nutritional Assessment Longitudinal Study-ELANA is a middle school cohort study conducted in Rio de Janeiro-Brazil in 2010-2012. Self-reported data on PA (International Physical Activity Questionnaire- IPAQ) and screen activities were obtained from 810 adolescents (mean ages of 10.9 years old (SD 0.78) for girls; 11 years old (SD 0.85) for boys) to perform autoregressive cross-lagged structural equation models in two time points for PA and three time points for screen activities. RESULTS: There was no significant stability of light PA and MVPA for boys and girls. Moderate stability of screen activities were found for both genders, with a significant coefficient of TV for boys (T1-T2:0.29; T2-T3:0.27 p<0.001); and VG for boys (T1-T2:0.33; T2-T3:0.35 p<0.001) and girls (T1-T2: 0.26; T2-T3:0.37 p<0.01). Significant lagged effects were obtained only among girls: light PA had effect on VG (-0.10 p<0.01), as well as in the opposite direction of TV on light PA (-0.03 p<0.01) and TV on MVPA (-0.11 p<0.01). CONCLUSION: The light PA, MVPA and screen activities (among girls) did not demonstrate stability over time. A warning scenario was suggested by the stability of high amounts of screen activities among boys over time. Screen activities had bidirectional association with light PA and MVPA among girls over time.


Assuntos
Exercício Físico , Comportamento Sedentário , Adolescente , Brasil , Criança , Estudos de Coortes , Feminino , Humanos , Estudos Longitudinais , Masculino , Autorrelato , Inquéritos e Questionários , Televisão , Jogos de Vídeo
10.
Geriatr Gerontol Int ; 18(8): 1280-1285, 2018 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-29717801

RESUMO

AIM: We aimed to estimate the factors associated with the biomedical dimension of successful aging (SA) and its prevalence in older Brazilian individuals. The conceptual framework for this approach relies on the considerable variation in the biophysiological effects of aging and the need to understand the factors that influence this process. METHODS: Data from a total of 845 older adults were analyzed. SA operationalization included the following criteria: good physical and cognitive performance, absence of disabilities, and good health conditions. Descriptive analyses were used to estimate the prevalence of SA, and the factors associated with SA were assessed using multivariate logistic regressions. RESULTS: The overall prevalence of SA was 25%, and the associated factors were the absence of (OR 10.5, 95% CI 5.2-21.1) or fewer than two physical morbidities (OR,3.5, 95% CI 2.1-5.9), body mass index in the overweight range (OR 1.8, 95% CI 1.02-3.3), absence of depression (OR ,2.1, 95% CI 1.07 = 4.1), high levels of physical activity (OR 1.88, 95% CI 1.14-3.2), high levels of social participation (OR 2.07, 95% CI 1.16-3.4) and younger age (65-74 years, OR 4.27, 95% CI 1.79-10.1; 75-84 years, OR 2.7, 95% CI 1.18-6.41). CONCLUSIONS: A small proportion of older adults met the criteria defining successful aging. Despite the great impact of biological determinants, modifiable social and lifestyle factors predicted successful aging in this population, suggesting that health promotion targeting behavioral changes might lead to tangible benefits for health and well-being in old age. Geriatr Gerontol Int 2018; 18: 1280-1285.


Assuntos
Envelhecimento/fisiologia , Exercício Físico/fisiologia , Fragilidade/diagnóstico , Fragilidade/epidemiologia , Sobrepeso/prevenção & controle , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Índice de Massa Corporal , Brasil , Estudos Transversais , Bases de Dados Factuais , Escolaridade , Feminino , Fragilidade/psicologia , Avaliação Geriátrica , Humanos , Estilo de Vida , Masculino , Análise Multivariada , Valor Preditivo dos Testes , Prevalência , Qualidade de Vida , Medição de Risco , Fatores Sexuais , Fatores Socioeconômicos
11.
Cad Saude Publica ; 34(5): e00029517, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29846405

RESUMO

The influence of neighborhood characteristics on self-rated health has been little studied. A multilevel approach using hierarchical models was applied to analyze the relationship between the socioeconomic characteristics in 621 neighborhoods (level 2) in the city of Rio de Janeiro, Brazil, and the self-rated health of 3,054 university employees (level 1) from the baseline of the Pró-Saúde Study. Neighborhoods were created using the SKATER algorithm (Spatial 'K'luster Analysis by Tree Edge Removal) to cluster census tracts according to four indicators and a minimum population of 5,000 people. After adjustment for individual factors (per capita income, schooling, age, sex, ethnicity, health-related behavior and chronic diseases), low level of neighborhood income and higher numbers of members per household were significantly associated with poor self-rated health. Participants living in medium income-level neighborhoods were 34% more likely to self-rate their health as being poor. Those living in areas with a higher density of members per household were 50% more likely to present poor self-rated health. Neighborhood context influences self-rated health, beyond the effect of individual factors. Worsening neighborhood socioeconomic conditions affect health adversely, which in turn increasing the chance of poor self-rated health.


Assuntos
Nível de Saúde , Características de Residência , Autorrelato , Fatores Socioeconômicos , Adulto , Brasil , Feminino , Humanos , Renda , Masculino , Pessoa de Meia-Idade , Pobreza/estatística & dados numéricos , Classe Social
12.
PLoS One ; 13(1): e0191253, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29342218

RESUMO

We investigated the stability and the directionality of being body bullied and a set of four variables- 1) Body Mass Index (BMI), 2) moderate and vigorous physical activity (MVPA), 3) television time (TV) and 4) video game/computer time (VG)-, termed in the present study as 'health-related state and behaviours (HRSB)'-across adolescence. The Adolescent Nutritional Assessment Longitudinal Study (ELANA) is a cohort study conducted among middle school students from two public and four private schools in Rio de Janeiro-Brazil. We analysed data from 2010 (T1) and 2012 (T2) among 810 adolescents (aged 9-15 at T1). Gender-specific structural equation models (SEM) were estimated, including autoregressive paths for the HRSB and being body bullied over time, correlations at T1 and T2, respectively, and cross-lagged effects. The results presented significant stability coefficients for almost all variables over time in both genders (except for MVPA in boys and girls and TV time among girls). There were positive correlations between BMI and being body bullied, as well as between TV and VG for boys (0.32, p<0.001 and 0.24, p<0.001, respectively) and girls (0.30, p<0.001 and 0.30, p<0.001, respectively) at T1. It remained significant at T2 (boys: 0.18, p<0.05 and 0.16, p<0.01; girls: 0.21, p<0.01 and 0.22, p<0.01, respectively). Examining the cross-lagged paths between being body bullied and HRSB, we observed that the reciprocal model provided the best fit for boys, indicating that BMI at T1 had a significant effect in being body bullied at T2 (0.12, p<0.05) and being body bullied at T1 had an effect on VG at T2 (0.14, p<0.01). Among girls the forward causation model showed the best fit, demonstrating a significant effect of being body bullied at T1 on VG at T2 (0.16, p<0.01). Apart from MVPA, both being body bullying and HRSB were largely stable across adolescence. For boys and girls alike, exposure to being body bullied seemed to increase their time spent on VG, while for boys BMI also predicted being body bullied. This study highlighted the complex interplay between being body bullied and HRSB and the importance of acknowledging gender differences in this context.


Assuntos
Bullying , Adolescente , Comportamento do Adolescente , Índice de Massa Corporal , Brasil , Bullying/estatística & dados numéricos , Criança , Estudos de Coortes , Exercício Físico , Feminino , Nível de Saúde , Humanos , Estudos Longitudinais , Masculino , Modelos Estatísticos , Avaliação Nutricional , Televisão , Jogos de Vídeo
13.
Diabetes Res Clin Pract ; 135: 192-198, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29155124

RESUMO

AIMS: The aim of this study was to evaluate the frequency of common mental disorders symptoms in adolescents with type 1 diabetes in comparison to a population-based sample of adolescents in Brazil. METHODS: We compared characteristics of 116 youth with type 1 diabetes and 73,508 youth without type 1 diabetes from the same population-based sample of adolescents aged 12-17years, taken from the Brazilian Study of Cardiovascular Risk in Adolescents (ERICA). We evaluated the 12-item General Health Questionnaire (GHQ) score, which is a self-administered screening survey for detecting mental health symptoms. Scores ≥3 were used to determine common mental disorder. RESULTS: Adolescents with and without type 1 diabetes were comparable with respect to age and race/ethnicity distributions. Youth with type 1 diabetes did not report higher scores on the weighted GHQ analyses in comparison to youth without type 1 diabetes (3.16, SE 0.76 vs. 2.10, SE 0.03, respectively; P = .167). No differences were found regarding the odds of having a GHQ score ≥3 (OR 1.48, 95% CI 0.72-3.08). However, analyses of mental health symptoms separately consistently showed that youth with type 1 diabetes more frequently endorsed mental health barriers in comparison to youth without type 1 diabetes. CONCLUSIONS: Mental health symptoms seem to be more frequent than diagnosis of common mental disorders in adolescents with type 1 diabetes, which may also interfere in glycemic control. Our findings highlight the need for appropriate mental health assessment in diabetes care in order to prevent glycemic control deterioration.


Assuntos
Diabetes Mellitus Tipo 1/complicações , Transtornos Mentais/etiologia , Saúde Mental/estatística & dados numéricos , Adolescente , Criança , Diabetes Mellitus Tipo 1/patologia , Feminino , Humanos , Masculino , Fatores de Risco , Inquéritos e Questionários
14.
Cad. Saúde Pública (Online) ; 34(5): e00029517, 2018. tab
Artigo em Inglês | LILACS | ID: biblio-952389

RESUMO

The influence of neighborhood characteristics on self-rated health has been little studied. A multilevel approach using hierarchical models was applied to analyze the relationship between the socioeconomic characteristics in 621 neighborhoods (level 2) in the city of Rio de Janeiro, Brazil, and the self-rated health of 3,054 university employees (level 1) from the baseline of the Pró-Saúde Study. Neighborhoods were created using the SKATER algorithm (Spatial 'K'luster Analysis by Tree Edge Removal) to cluster census tracts according to four indicators and a minimum population of 5,000 people. After adjustment for individual factors (per capita income, schooling, age, sex, ethnicity, health-related behavior and chronic diseases), low level of neighborhood income and higher numbers of members per household were significantly associated with poor self-rated health. Participants living in medium income-level neighborhoods were 34% more likely to self-rate their health as being poor. Those living in areas with a higher density of members per household were 50% more likely to present poor self-rated health. Neighborhood context influences self-rated health, beyond the effect of individual factors. Worsening neighborhood socioeconomic conditions affect health adversely, which in turn increasing the chance of poor self-rated health.


Existem relativamente poucos estudos sobre a influência das características de vizinhança sobre a auto-avaliação da saúde. Foi aplicada uma abordagem multinível com modelos hierárquicos para analisar a relação entre as características socioeconômicas de 621 vizinhanças (nível 2) da cidade do Rio de Janeiro, Brasil, e a auto-avaliação da saúde de 3.054 servidores universitários (nível 1) da linha de base do Estudo Pró-Saúde. As vizinhanças foram criadas pela aplicação do algoritmo SKATER (Spatial 'K'luster Analysis by Tree Edge Removal) aos setores censitários, de acordo com quatro indicadores e uma população mínima de 5 mil habitantes. Depois de ajustar para fatores individuais (renda per capita, escolaridade, idade, sexo, raça/cor, comportamentos relacionados à saúde e doenças crônicas), houve uma associação significativa entre renda baixa e número maior de pessoas por domicílio na vizinhança e autoavaliação da saúde "ruim". Os residentes de vizinhanças de renda média apresentaram probabilidade 34% maior de avaliar a própria saúde como "ruim". Aqueles que viviam em vizinhanças com maior número médio de pessoas por domicílio mostraram uma probabilidade 50% maior de autoavaliação da saúde "ruim". Para além de fatores individuais, o contexto de vizinhança influencia a autoavaliação da saúde. Piores condições socioeconômicas da vizinhança afetam negativamente a saúde, que por sua vez aumenta as chances de autoavaliação da saúde "ruim".


La influencia de las características del vecindario en la salud autoevaluada se ha estudiado escasamente. Se aplicó un análisis multinivel usando modelos jerárquicos para analizar la relación entre las características socioeconómicas en 621 vecindarios (nivel 2), dentro de la ciudad de Río de Janeiro, Brasil, y la salud autoevaluada de 3.054 empleados universitarios (nivel 1), procedentes de la base de referencia del Estudio Pró-Saúde. Se crearon vecindarios con el uso del algoritmo SKATER (Spatial 'K'luster Analysis by Tree Edge Removal), con el fin de agrupar secciones del censo, de acuerdo con cuatro indicadores y una población mínima de 5.000 personas. Tras el ajuste por factores individuales (ingresos per cápita, escolarización, edad, sexo, etnia, comportamiento informado de salud y enfermedades crónicas), el bajo nivel de ingresos en el vecindario y el alto número de miembros por hogar estuvieron significativamente asociados a un escasa salud autoevaluada. Los participantes que vivían en vecindarios con un nivel de ingresos medios tuvieron una probabilidad un 34% mayor de autoevaluar su salud más bien como mala. Quienes estaban viviendo en vecindarios con una densidad más alta de miembros por vivienda tuvieron una probabilidad de un 50% mayor de presentar una salud autoevaluada mala. El contexto del vecindario influencia la salud autoevaluada, además del efecto de los factores individuales. Un empeoramiento de las condiciones socioeconómicas en el vecindario afecta adversamente a la salud, que a su vez aumenta la oportunidad de una salud autoevaluada como mala.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Fatores Socioeconômicos , Características de Residência , Nível de Saúde , Autorrelato , Pobreza/estatística & dados numéricos , Classe Social , Brasil , Renda
15.
Stem Cell Reports ; 9(2): 667-680, 2017 08 08.
Artigo em Inglês | MEDLINE | ID: mdl-28712846

RESUMO

Amyotrophic lateral sclerosis (ALS) is a fatal and rapidly progressing motor neuron disease. Astrocytic factors are known to contribute to motor neuron degeneration and death in ALS. However, the role of astrocyte in promoting motor neuron protein aggregation, a disease hallmark of ALS, remains largely unclear. Here, using culture models of human motor neurons and primary astrocytes of different genotypes (wild-type or SOD1 mutant) and reactive states (non-reactive or reactive), we show that reactive astrocytes, regardless of their genotypes, reduce motor neuron health and lead to moderate neuronal loss. After prolonged co-cultures of up to 2 months, motor neurons show increased axonal and cytoplasmic protein inclusions characteristic of ALS. Reactive astrocytes induce protein aggregation in part by releasing transforming growth factor ß1 (TGF-ß1), which disrupts motor neuron autophagy through the mTOR pathway. These results reveal the important contribution of reactive astrocytes in promoting aspects of ALS pathology independent of genetic influences.


Assuntos
Astrócitos/metabolismo , Autofagia , Neurônios Motores/metabolismo , Agregação Patológica de Proteínas , Fator de Crescimento Transformador beta1/metabolismo , Esclerose Lateral Amiotrófica/etiologia , Esclerose Lateral Amiotrófica/metabolismo , Esclerose Lateral Amiotrófica/patologia , Animais , Astrócitos/patologia , Axônios/metabolismo , Sobrevivência Celular/genética , Células Cultivadas , Citoplasma/metabolismo , Modelos Animais de Doenças , Humanos , Filamentos Intermediários/metabolismo , Camundongos , Mutação , Agregados Proteicos/genética , Transdução de Sinais , Superóxido Dismutase-1/genética , Superóxido Dismutase-1/metabolismo , Serina-Treonina Quinases TOR/metabolismo
16.
BMC Public Health ; 16: 977, 2016 09 15.
Artigo em Inglês | MEDLINE | ID: mdl-27630121

RESUMO

BACKGROUND: Psychological well-being influences health behaviours differently in adolescent boys and girls. We evaluated the role of psychological well-being in early adolescence in the onset and persistence of insufficient physical activity and exceeding recommended screen time, depending on gender. METHODS: This work derives from a cohort study called Longitudinal Study of Adolescent Nutritional Assessment conducted among elementary school students from two public and four private schools in Rio de Janeiro, Brazil from 2010-2013. We analysed data from 2010 and 2012 from 526 adolescents. Physical activity was evaluated using the International Physical Activity Questionnaire. Those who performed less than 60 min per day of moderate to vigorous physical activity (MVPA) were classified as insufficiently active. Screen time was evaluated based on daily time spent in front of television, video games, and computers. Those who had 4 h or more screen time per day were classified as exceeding the recommended time. Psychological well-being was assessed using the psychological domain of the KIDSCREEN 27 questionnaire. Linear regression was used to estimate coefficient (ß) and r (2) values for continuous variables. Relative risks (RR) and confidence intervals (95 % CI) for onset and persistence of insufficient activity and exceeding recommended screen time were estimated with Poisson regression models. RESULTS: Among girls, linear regression analyses showed a significant inverse association between psychological well-being and screen minutes per day at T2 (r (2) = 0.049/ß = -3.81 (95 % CI -7.0, -0.9)), as well as an association between poor psychological well-being and onset of exceeding recommended screen time in categorical analyses (RR crude: 1.3; CI 95 % 1.1, 1.7; RR adjusted: 1.3; CI 95 % 1.0, 1.6). For boys, an association was found between psychological well-being and onset of insufficient activity 2 years later (RR crude: 1.3; CI 95 % 1.2, 1.4; RR adjusted: 1.2; CI 95 % 1.1, 1.4). CONCLUSION: Adolescence is crucial for the development of unhealthy behaviours related to psychological well-being status in the context of a middle-income country. Gender differences are important because poor psychological well-being seems to affect sedentary behaviour in girls more than in boys, and predicts insufficient activity among boys.


Assuntos
Computadores/estatística & dados numéricos , Exercício Físico/psicologia , Estudantes/estatística & dados numéricos , Televisão/estatística & dados numéricos , Jogos de Vídeo/estatística & dados numéricos , Adolescente , Brasil , Feminino , Comportamentos Relacionados com a Saúde , Humanos , Modelos Lineares , Estudos Longitudinais , Masculino , Risco , Instituições Acadêmicas , Comportamento Sedentário , Fatores Sexuais , Estudantes/psicologia , Inquéritos e Questionários , Fatores de Tempo
17.
Ann Occup Hyg ; 60(5): 567-80, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-27026660

RESUMO

OBJECTIVES: Changes in the modern economy have affected the financial sector. Time pressures, excessive work demands, and job stress are frequent concerns among bank employees, which might predispose them to burnout symptoms. The objective of the present study was to investigate the association between burnout symptoms and exposure to psychosocial work conditions in bank employees. METHODS: A cross-sectional study of 1046 bank employees was carried out in Pará and Amapá, northern Brazil. We applied a self-administered questionnaire evaluating socio-demographic characteristics, burnout (Maslach Burnout Inventory), and two job stress models (Demand-Control-Support and Effort-Reward Imbalance). Two levels of burnout symptoms were analysed: moderate level of burnout (MLB) and high level of burnout (HLB). Logistic regression models were used to estimate associations between the two levels of burnout and the two stress models, controlling for relevant covariates. RESULTS: The overall prevalence of burnout was 71.8% (31.1% for HLB; 40.7% for MLB), regardless of gender. Exposure to adverse psychosocial conditions in the workplace, such as high strain, low social support at work, high effort/low reward, and over commitment showed strong association with HLB and MLB, and these associations were independent of age, gender, and other occupational characteristics. CONCLUSIONS: We found that psychosocial conditions in the financial sector involving high strain, low social support at work, high effort/low reward, and over commitment represent possible risk factors for moderate and HLB symptoms in bank employees.


Assuntos
Contabilidade , Esgotamento Profissional/epidemiologia , Local de Trabalho , Adulto , Idoso , Brasil , Esgotamento Profissional/psicologia , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Apoio Social , Inquéritos e Questionários , Adulto Jovem
18.
Rev Saude Publica ; 50 Suppl 1: 14s, 2016 Feb.
Artigo em Inglês, Português | MEDLINE | ID: mdl-26910549

RESUMO

OBJECTIVE To describe the prevalence of common mental disorders in Brazilian adolescent students, according to geographical macro-regions, school type, sex, and age. METHODS We evaluated 74,589 adolescents who participated in the Cardiovascular Risk Study in Adolescents (ERICA), a cross-sectional, national, school-based study conducted in 2013-2014 in cities with more than 100,000 inhabitants. A self-administered questionnaire and an electronic data collector were employed. The presence of common mental disorders was assessed using the General Health Questionnaire (GHQ-12). We estimated prevalence and 95% confidence intervals of common mental disorders by sex, age, and school type, in Brazil and in the macro-regions, considering the sample design. RESULTS The prevalence of common mental disorders was of 30.0% (95%CI 29.2-30.8), being higher among girls (38.4%; 95%CI 37.1-39.7) when compared to boys (21.6%; 95%CI 20.5-22.8), and among adolescents who were from 15 to 17 years old (33.6%; 95%CI 32.2-35.0) compared to those aged between 12 and 14 years (26.7%; 95%CI 25.8-27.6). The prevalence of common mental disorders increased with age for both sexes, always higher in girls (ranging from 28.1% at 12 years to 44.1% at 17 years) than in boys (ranging from 18.5% at 12 years to 27.7% at 17 years). We did not observe any significant difference by macro-region or school type. Stratified analyses showed higher prevalence of common mental disorders among girls aged from 15 to 17 years of private schools in the North region (53.1; 95%CI 46.8-59.4). CONCLUSIONS The high prevalence of common mental disorders among adolescents and the fact that the symptoms are often vague mean these disorders are not so easily identified by school administrators or even by health services. The results of this study can help the proposition of more specific prevention and control measures, focused on highest risk subgroups.


Assuntos
Transtornos Mentais/epidemiologia , Adolescente , Brasil/epidemiologia , Métodos Epidemiológicos , Feminino , Humanos , Masculino , Características de Residência , Fatores Sexuais , Fatores Socioeconômicos , Estudantes/estatística & dados numéricos
19.
Rev. saúde pública ; 50(supl.1): 14s, Feb. 2016. tab, graf
Artigo em Português | LILACS | ID: lil-774644

RESUMO

ABSTRACT OBJECTIVE To describe the prevalence of common mental disorders in Brazilian adolescent students, according to geographical macro-regions, school type, sex, and age. METHODS We evaluated 74,589 adolescents who participated in the Cardiovascular Risk Study in Adolescents (ERICA), a cross-sectional, national, school-based study conducted in 2013-2014 in cities with more than 100,000 inhabitants. A self-administered questionnaire and an electronic data collector were employed. The presence of common mental disorders was assessed using the General Health Questionnaire (GHQ-12). We estimated prevalence and 95% confidence intervals of common mental disorders by sex, age, and school type, in Brazil and in the macro-regions, considering the sample design. RESULTS The prevalence of common mental disorders was of 30.0% (95%CI 29.2-30.8), being higher among girls (38.4%; 95%CI 37.1-39.7) when compared to boys (21.6%; 95%CI 20.5-22.8), and among adolescents who were from 15 to 17 years old (33.6%; 95%CI 32.2-35.0) compared to those aged between 12 and 14 years (26.7%; 95%CI 25.8-27.6). The prevalence of common mental disorders increased with age for both sexes, always higher in girls (ranging from 28.1% at 12 years to 44.1% at 17 years) than in boys (ranging from 18.5% at 12 years to 27.7% at 17 years). We did not observe any significant difference by macro-region or school type. Stratified analyses showed higher prevalence of common mental disorders among girls aged from 15 to 17 years of private schools in the North region (53.1; 95%CI 46.8-59.4). CONCLUSIONS The high prevalence of common mental disorders among adolescents and the fact that the symptoms are often vague mean these disorders are not so easily identified by school administrators or even by health services. The results of this study can help the proposition of more specific prevention and control measures, focused on highest risk subgroups.


RESUMO OBJETIVO Descrever a prevalência de transtornos mentais comuns em adolescentes escolares brasileiros, segundo macrorregiões, tipo de escola, sexo e idade. MÉTODOS Foram avaliados 74.589 adolescentes participantes do Estudo de Riscos Cardiovasculares em Adolescentes (ERICA), estudo transversal, nacional, de base escolar, realizado em 2013-2014 em municípios com mais de 100 mil habitantes. Utilizou-se questionário autopreenchível e coletor eletrônico de dados. Presença de transtornos mentais comuns foi avaliada por meio do General Health Questionnaire (GHQ-12). Estimaram-se prevalências e intervalos de confiança de 95% de transtornos mentais comuns por sexo, idade e tipo de escola, no Brasil e nas macrorregiões, considerando o desenho da amostra. RESULTADOS A prevalência de transtornos mentais comuns foi de 30,0% (IC95% 29,2-30,8), sendo mais elevada entre meninas (38,4%; IC95% 37,1-39,7), quando comparadas aos meninos (21,6%; IC95% 20,5-22,8) e entre os adolescentes de 15 a 17 anos (33,6%; IC95% 32,2-35,0), em relação àqueles entre 12 e 14 anos (26,7%; IC95% 25,8-27,6). As prevalências de transtornos mentais comuns aumentaram conforme a idade, para ambos os sexos, sempre maior nas meninas (variando de 28,1% aos 12 anos, até 44,1% aos 17 anos), do que nos meninos (variando de 18,5% aos 12 anos até 27,7% aos 17 anos). Não houve diferença importante por macrorregião ou tipo de escola. Análises estratificadas mostraram maior prevalência de transtornos mentais comuns entre meninas de 15 a 17 anos de escolas privadas da região Norte (53,1; IC95% 46,8-59,4). CONCLUSÕES A elevada prevalência de transtornos mentais comuns entre os adolescentes e o fato de os sintomas serem muitas vezes vagos fazem com que esses transtornos sejam pouco identificados por gestores escolares ou mesmo serviços de saúde. Os resultados deste estudo podem ajudar na proposição de medidas de prevenção e controle mais específicas e voltadas para os subgrupos sob maior risco.


Assuntos
Humanos , Masculino , Feminino , Adolescente , Transtornos Mentais/epidemiologia , Fatores Socioeconômicos , Estudantes/estatística & dados numéricos , Brasil/epidemiologia , Características de Residência , Fatores Sexuais , Métodos Epidemiológicos
20.
Geriatr Gerontol Int ; 16(3): 336-44, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25869919

RESUMO

AIM: The present study estimated the prevalence of fear of falling in older adults, and its associations with clinical, functional and psychosocial factors. METHODS: Data from the Research Network Frailty in Brazilian Older People, specifically the Rio de Janeiro Study involving participants aged 65 years and older residing in the city of Rio de Janeiro, Brazil, were analyzed. Fear of falling was assessed by the Brazilian version of Falls Efficacy Scale-International. The following variables were assessed: history of falls, fracture after fall, number of comorbidities, number of medications, hospitalization in the previous year, use of walking support device, functional dependency in activities of daily living (including instrumental activities), hearing and visual impairments, hand grip strength, walking speed, self-rated health, depressive symptoms, cognitive impairment, living alone, social support, and activity level. Associations were evaluated by multiple logistic regression. RESULTS: Among the 742 participants, 51.9% had a fear of falling, which was more prevalent in women and older participants. Fear of falling was associated with a history of one to two falls (odds ratio [OR] 2.18; 95% confidence interval [CI] 1.42-3.36), three or more falls (OR 2.72, 95% CI 1.10-6.70), use of seven or more medications (OR 1.70, 95%CI 1.04-2.80), hearing impairment (OR 1.66, 95% CI 1.10-2.49), functional dependence in activities of daily living (OR 1.73, 95% CI 1.07-2.79), diminished gait speed (OR 1.64 95% CI 1.04-2.58), fair self-rated health (OR 1.89, 95% CI, 1.30-2.74), poor/very poor self-rated health (OR 4.92, 95% CI 1.49-16.27) and depressive symptoms (OR 1.68, 95% CI 1.07-2.63). CONCLUSIONS: The prevalence of fear of falling was high in this population, and was associated with history of falls, use of seven or more medications, hearing impairment, functional dependency in activities of daily living, diminished walking speed, fair and poor/very poor self-rated health and depressive symptoms.


Assuntos
Acidentes por Quedas/estatística & dados numéricos , Medo , Idoso Fragilizado/psicologia , Idoso , Idoso de 80 Anos ou mais , Brasil , Estudos Transversais , Feminino , Humanos , Masculino , Fatores Socioeconômicos
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