Measuring school level attributable risk to support school-based HPV vaccination programs.

BACKGROUND: In Australia in 2017, 89% of 15-year-old females and 86% of 15-year-old males had received at least one dose of the HPV vaccine. However, considerable variation in HPV vaccination initiation (dose one) across schools remains. It is important to understand the school-level characteristics most strongly associated with low initiation and their contribution to the overall between-school variation. METHODS: A population-based ecological analysis was conducted using school-level data for 2016 on all adolescent students eligible for HPV vaccination in three Australian jurisdictions. We conducted logistic regression to determine school-level factors associated with lower HPV vaccination initiation (< 75% dose 1 uptake) and estimated the population attributable risk (PAR) and the proportion of schools with the factor (school-level prevalence). RESULTS: The factors most strongly associated with lower initiation, and their prevalence were; small schools (OR = 9.3, 95%CI = 6.1-14.1; 33% of schools), special education schools (OR = 5.6,95%CI = 3.7-8.5; 8% of schools), higher Indigenous enrolments (OR = 2.7,95% CI:1.9-3.7; 31% of schools), lower attendance rates (OR = 2.6,95%CI = 1.7-3.7; 35% of schools), remote location (OR = 2.6,95%CI = 1.6-4.3; 6% of schools,) and lower socioeconomic area (OR = 1.8,95% CI = 1.3-2.5; 33% of schools). The highest PARs were small schools (PAR = 79%, 95%CI:76-82), higher Indigenous enrolments (PAR = 38%, 95%CI: 31-44) and lower attendance rate (PAR = 37%, 95%CI: 29-46). CONCLUSION: This analysis suggests that initiatives to support schools that are smaller, with a higher proportion of Indigenous adolescents and lower attendance rates may contribute most to reducing the variation of HPV vaccination uptake observed at a school-level in these jurisdictions. Estimating population-level coverage at the school-level is useful to guide policy and prioritise resourcing to support school-based vaccination programs.

Differences in school factors associated with adolescent HPV vaccination initiation and completion coverage in three Australian states.

BACKGROUND: Schools are the primary setting for the delivery of adolescent HPV vaccination in Australia. Although this strategy has achieved generally high vaccination coverage, gaps persist for reasons that are mostly unknown. This study sought to identify school-level correlates of low vaccination course initiation and completion in New South Wales, Tasmania, and Western Australia to inform initiatives to increase uptake. METHODS: Initiation was defined as the number of first doses given in a school in 2016 divided by vaccine-eligible student enrolments. Completion was the number of third doses given in a school in 2015-2016 divided by the number of first doses. Low initiation and completion were defined as coverage ≤ 25thpercentile of all reporting schools. We investigated correlations between covariates using Spearman's rank correlation coefficients. Due to multicollinearity, we used univariable logistic regression to investigate associations between school characteristics and low coverage. RESULTS: Median initiation was 84.7% (IQR: 75.0%-90.4%) across 1,286 schools and median completion was 93.8% (IQR: 86.0%-97.3%) across 1,295 schools. There were strong correlations between a number of school characteristics, particularly higher Indigenous student enrolments and lower attendance, increasing remoteness, higher postcode socioeconomic disadvantage, and smaller school size. Characteristics most strongly associated with low initiation in univariate analyses were small school size, location in Tasmania, and schools catering for special educational needs. Low completion was most strongly associated with schools in Tasmania and Western Australia, remote location, small size, high proportion of Indigenous student enrolments, and low attendance rates. CONCLUSION: This study provides indicative evidence that characteristics of schools and school populations are associated with the likelihood of low initiation and completion of the HPV vaccination course. The findings will guide further research and help target initiatives to improve vaccination uptake in schools with profiles associated with lower coverage.

The effects of readers' goals on inference generation and memory for texts.

We investigated the effects of readers' goals on inference generation and memory for expository text. College students (N = 82) read texts for the purpose of either study or entertainment. On-line inference generation was recorded via think-aloud procedures, and off-line memory was assessed via free recall. Reading goal strongly influenced inferential activity: Readers with a study goal produced more coherence-building (i.e., backward/explanatory and forward/predictive) inferences, whereas readers with an entertainment goal produced more associations and evaluations. These differences were associated with superior memory for the texts in the study condition. The results indicate that inference generation during reading is partly strategic and is influenced systematically by reading purpose. We propose that reading goals influence readers' standards of coherence, which in turn influence the types of inferences that they draw and the final memory representations that they construct.

Effects of headings and familiarity with a text on strategies for searching a text.

College students were videotaped while they searched chapter-length texts for answers to specific questions. The texts either did not contain headings or contained one of three types of headings that varied in the information that they provided about text organization and content. Familiarity with the text was varied by manipulating (1) the number of prior searches of the text and (2) whether or not the text was read before searching. Measures were taken of the time spent examining each page and of the sequence of examination of pages. Cluster analyses of the search measures revealed that familiarity with the text influenced a searcher's strategy for selecting which pages to examine. Once a page was selected for examination, both headings and familiarity influenced how the page was inspected.

The relation of story structure properties to recall of television stories in young children with attention-deficit hyperactivity disorder and nonreferred peers.

In this study, the authors examined memory for televised stories to gain insight into similarities and differences in story comprehension between young children with attention-deficit hyperactivity disorder (ADHD) and their typical peers. In particular, the authors investigated the extent to which 4- to 6-year-old children's free recall of story events is predicted by several structural properties of story events (number of causal connections, whether an event is on or off the story's causal chain, story-grammar category, and position in the story's hierarchical structure), whether differences exist between children with ADHD and nonreferred comparison children in their sensitivity to structural features of stories, and whether age differences in sensitivity to structural features are similar for both groups. For both groups, recall of story events was predicted by all four structural properties, but the effects of the two causal properties was stronger for comparison children than for children with ADHD. Further examination revealed that this difference was observed only when a competing activity was available during television viewing. These findings indicate that both groups of preschool children are able to benefit from causal structure when recalling television stories, but that children with ADHD lose this benefit when attention is divided. Consistent with previous findings for nonreferred children (P. W. van den Broek, E. P. Lorch, & R. Thurlow, 1996), in both diagnostic groups the effects of causal properties increased across age, and older children were more likely to include causally important protagonists' goals in their recalls than younger children.

Regression analyses of repeated measures data in cognitive research.

Repeated measures designs involving nonorthogonal variables are being used with increasing frequency in cognitive psychology. Researchers usually analyze the data from such designs inappropriately, probably because the designs are not discussed in standard textbooks on regression. Two commonly used approaches to analyzing repeated measures designs are considered in this article. It is argued that both approaches use inappropriate error terms for testing the effects of independent variables. A more appropriate analysis is presented, and two alternative computational procedures for the analysis are illustrated.

Distractibility and vocabulary deficits in children with spina bifida and hydrocephalus.

This experiment tested the hypothesis that children with spina bifida and hydrocephalus (SBH) are more distractible than normal children, and that the distractibility partially accounts for the language deficits of these children. In Part 1, 15 of these children of primary-school age were compared with controls matched for mental age on a non-verbal task during which irrelevant stimuli were present or absent. Interference effects of the irrelevant stimuli were larger and more persistent for the SBH children. In Part 2, the children and their controls were tested for comprehension of relational words, with and without irrelevant information. The two groups performed similarly when there was no irrelevant information, but the SBH children exhibited vocabulary deficiencies when irrelevant items were present. These findings support the original hypothesis of a relationship between distractibility and language deficits.