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Rev Esp Patol ; 55 Suppl 1: S49-S53, 2022 09.
Artigo em Espanhol | MEDLINE | ID: mdl-36075663

RESUMO

Germ cell tumors are the most frequent neoplasia in young males. The aims of this study is to describe a case in which a postpuberal teratoma suffers a transformation to choriocarcinoma and metastasize to stomach. We have made a systematic review in PubMed and consensus documents to study this mismatch between the tumour, metastasis and the exception of gastric metastatic affectation. We describe three options to explain this discordance: a mixed germ cells tumour, a burned out tumour or a germ cells tumour derived from a malignant germ cell tumour precursor or different clonal strains. After made a thorough investigation we conclude that the most truly option is the last one as we extensive explain below. Once the gastric metastatic lesions are extremely rare and reach to <5%, but there are not conclusive assessments.


Assuntos
Coriocarcinoma , Neoplasias Embrionárias de Células Germinativas , Teratoma , Coriocarcinoma/patologia , Feminino , Humanos , Masculino , Gravidez , Estômago/patologia , Teratoma/patologia , Teratoma/secundário
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