Cross-sectional analysis of a cohort of people over 65 years of age living with HIV.

INTRODUCTION: This study aims to describe and analyze the characteristics of aged people who are living with HIV (APHIV) and evaluate their association on the comorbidities they currently have. METHODS: Cross-sectional analysis of APHIV under active follow-up at the Infectious Diseases Unit of the University Clinical Hospital of Santiago de Compostela. Demographic and clinical data were analyzed, along with their association with the development of comorbidities in this population. A correlation and multiple linear regression analysis were performed for this purpose. RESULTS: Eighty-five APHIV, 65 males and 20 females, with an average age of 69 years (IQR 8) and a duration of living with HIV of 17 years (SD 7), were studied. 41% of them had their initial diagnosis with AIDS. The most common comorbidities are hypertension and dyslipidemia in 55% and 52%, respectively. 40% of APHIV take at least 5 medications. 35% have received more than 5 lines of antiretroviral treatment. At the time of analysis, all APHIV have an undetectable viral load. No significant association was observed between the number of comorbidities and various characteristics of APHIV; however, a weak correlation was noted among age, the cumulative number of antiretroviral treatments received throughout their lives, and the number of comorbidities. CONCLUSIONS: This analysis highlights the substantial burden of comorbidities and polypharmacy experienced by APHIV. Further studies are needed to better understand the characteristics and variables influencing their development.

[HIV infection in patients aged 50 years or older in the HAART era]. / Infección por VIH en pacientes mayores de 50 años en la etapa TARGA.

There is little information on patients 50 years or older with HIV infection since the start of the HAART era. We performed a descriptive cross-sectional study during 2004 including 28 patients aged 52 to 87 years. Eighteen patients were men (64%) and sexual transmission was the risk factor in 23 (81%). Four patients (14%) fulfilled slow progression criteria and 13 (46%) belonged to the C3 category. Twenty-four patients were on HAART, with optimal adherence. All the patients were receiving HIV-unrelated medications to treat comorbid conditions. Hence, the profile of these patients is as follows: mainly male with sexually transmitted infection, severe immunodeficiency at the diagnosis, and frequent comorbid processes.

Infección por VIH en pacientes mayores de 50 años en la etapa TARGA / HIV infection in patients aged 50 years or older in the HAART era

Existe poca información de los pacientes mayores de 50 años con infección por virus de la inmunodeficiencia humana (VIH) desde el inicio de la terapia antirretroviral de gran actividad (TARGA). Presentamos el estudio transversal descriptivo en 2004 de 28 pacientes (edades entre 52 y 87 años), 18 varones (64%). Contagio por vía sexual, 23 pacientes (81%). Cuatro (14%) son progresadores lentos, 13 (46%) categoría C3. Veinticuatro están con TARGA con alta adherencia al tratamiento. Todos realizan tratamiento con otras medicaciones por comorbilidades asociadas. El paciente tipo es un varón, heterosexual, grave inmunodeficiencia al diagnóstico y frecuente comorbilidad asociada (AU)

There is little information on patients 50 years or older with HIV infection since the start of the HAART era. We performed a descriptive cross-sectional study during 2004 including 28 patients aged 52 to 87 years. Eighteen patients were men (64%) and sexual transmission was the risk factor in 23 (81%). Four patients (14%) fulfilled slow progression criteria and 13 (46%) belonged to the C3 category. Twenty-four patients were on HAART, with optimal adherence. All the patients were receiving HIV-unrelated medications to treat comorbid conditions. Hence, the profile of these patients is as follows: mainly male with sexually transmitted infection, severe immunodeficiency at the diagnosis, and frequent comorbid processes (AU)

Epidemiología de la infección por el VIH en el Área de Santiago de Compostela: cambio de espectro en el período 1989-2004 / Epidemiology of human immunodeficiency virus (HIV) in Santiago de Compostela (Galicia-Spain): changing picture along 1989-2004

No disponible