RESUMO
Allyl 1-naphthyl ethers are useful compounds for different purposes, but reported methods to synthesize them require long reaction times. In this work, we have obtained allyl 1-naphthyl ether in good yield using ultrasonic-assisted methodology in a 1-h reaction. A central composite design was used to obtain a statistical model and a response surface (p < 0.05; R2 = 0.970; R2adj = 0.949; R2 pred = 0.818) that can predict the optimal conditions to maximize the yield, validated experimentally.
Assuntos
Compostos Alílicos/análise , Compostos Alílicos/provisão & distribuição , Compostos Alílicos/síntese química , Éteres/análise , Éteres/provisão & distribuição , Metodologia como Assunto , Ultrassom/métodosRESUMO
Allyl 1-naphthyl ethers are useful compounds for different purposes, but reported methods to synthesize them require long reaction times. In this work, we have obtained allyl 1-naphthyl ether in good yield using ultrasonic-assisted methodology in a 1-h reaction. A central composite design was used to obtain a statistical model and a response surface (p<0.05; R(2)=0.970; R(2)(adj)=0.949; R(2)(pred)=0.818) that can predict the optimal conditions to maximize the yield, validated experimentally.