Cyclic lava effusion during the 2018 eruption of Kilauea Volcano.

Lava flows present a recurring threat to communities on active volcanoes, and volumetric eruption rate is one of the primary factors controlling flow behavior and hazard. The time scales and driving forces of eruption rate variability, however, remain poorly understood. In 2018, a highly destructive eruption occurred on the lower flank of Kilauea Volcano, Hawai'i, where the primary vent exhibited substantial cyclic eruption rates on both short (minutes) and long (tens of hours) time scales. We used multiparameter data to show that the short cycles were driven by shallow outgassing, whereas longer cycles were pressure-driven surges in magma supply triggered by summit caldera collapse events 40 kilometers upslope. The results provide a clear link between eruption rate fluctuations and their driving processes in the magmatic system.

ERBIN deficiency links STAT3 and TGF-ß pathway defects with atopy in humans.

Nonimmunological connective tissue phenotypes in humans are common among some congenital and acquired allergic diseases. Several of these congenital disorders have been associated with either increased TGF-ß activity or impaired STAT3 activation, suggesting that these pathways might intersect and that their disruption may contribute to atopy. In this study, we show that STAT3 negatively regulates TGF-ß signaling via ERBB2-interacting protein (ERBIN), a SMAD anchor for receptor activation and SMAD2/3 binding protein. Individuals with dominant-negative STAT3 mutations (STAT3mut ) or a loss-of-function mutation in ERBB2IP (ERBB2IPmut ) have evidence of deregulated TGF-ß signaling with increased regulatory T cells and total FOXP3 expression. These naturally occurring mutations, recapitulated in vitro, impair STAT3-ERBIN-SMAD2/3 complex formation and fail to constrain nuclear pSMAD2/3 in response to TGF-ß. In turn, cell-intrinsic deregulation of TGF-ß signaling is associated with increased functional IL-4Rα expression on naive lymphocytes and can induce expression and activation of the IL-4/IL-4Rα/GATA3 axis in vitro. These findings link increased TGF-ß pathway activation in ERBB2IPmut and STAT3mut patient lymphocytes with increased T helper type 2 cytokine expression and elevated IgE.

Dates and date pits as ingredients in broiler starting and coturnix quail breeder diets.

Two broiler growth and two quail breeder studies were conducted to evaluate the dietary potential of dates, date meat, and date pits. The test ingredients were incorporated in broiler starting diets at levels ranging from 8 to 43% dates, 16 to 43% date meat, and 5 to 27% date pits. The quail breeder diet had ingredient ranges of 10 to 30% dates, 8 to 24% date meat, and 5 to 15% date pits. The date ingredient diets supported broiler weights and feed conversions comparable to or better than the control diet. Quail breeder feed consumption decreased at the 30% date level; however in the second trial 24% dates supported normal intake. Egg production and egg weight on all date and date part diets were equal to those of the control.

Effect of inorganic phosphate source and dietary phosphorus level on laying hen performance and eggshell quality.

Two experiments were conducted to evaluate laying hen performance when fed two sources of inorganic phosphorus. In Experiment 1, a regular and a coarse form of defluorinated phosphate and one source of dicalcium phosphate were used in diets calculated to contain either .4 or .5% total phosphorus (.2 or .3% nonphytate phosphorus). In Experiment 2, either the regular form of defluorinated phosphate or the dicalcium phosphate source was fed in diets calculated to contain either .4, .5, .6, or .7% total phosphorus (.2, .3, .4, or .5% nonphytate phosphorus). In Experiment 1, hens fed .5% total dietary phosphorus consumed more feed and produced heavier eggs (P less than or equal to .05). Hens fed the .4% dietary phosphorus level lost more weight during the experiment (P less than or equal to .05). No differences among dietary treatments existed for egg specific gravity. A significant source by level interaction occurred for the farm classification of thin-shelled, cracked, or broken eggs and for the total of these classifications. In Experiment 2, egg production, feed consumption, egg weight, and egg mass were depressed (P less than or equal to .05) at the .4% total dietary phosphorus level. Hens fed the .4 and .7% total dietary phosphorus level laid eggs with the highest and lowest egg specific gravity, respectively. This trend was inverse to the effect of these phosphorus levels on egg weights. A significant source by level interaction occurred for the farm classification of thin shell and for the total percentage of eggs with exterior defects. At the .4% total phosphorus level, the regular form of defluorinated phosphate produced eggs with a significantly greater thin shell classification than the dicalcium phosphate source. Hens fed the dicalcium phosphate source produced a higher percentage of compressed-sided and misshapen eggs.

Influence of wet and dry feed on laying hens under heat stress.

Two experiments were carried out with a split-plot design over time using White Leghorn hens, 161 days of age. The experiments were conducted to determine the effect of two ambient temperatures (21.1 versus 29.4 C in Experiment 1 and 21.1 versus 33.3 C in Experiment 2) on feed and water consumption using four dietary regimens. The day was divided into two feeding periods: a.m. (0600 to 1300 h) and p.m. (1300 to 0600 h the next morning). The four regimens were as follows: dry feed during both a.m. and p.m. periods; dry feed during a.m. period and wet feed (50% moisture) during the p.m. period; wet feed in the a.m. and dry feed in the p.m.; and wet feet during both a.m. and p.m. periods. The hens were maintained on a 14 h light: 10 h dark lighting program. The hens consumed the greatest quantity of DM and water during the p.m. period, regardless of the environmental temperature to which the hens were exposed. Constant heat stress at 29.4 and 33.3 increased (P less than or equal to .05) drinking water intake during the a.m. but not during the p.m. period. The use of wet feed and dry-wet feed provided a 38 and 48% increase (P less than or equal to .05), respectively, in DM intake when compared with the use of dry feed at 33.3 C. Exposure of laying hens to high environmental temperatures (29.4 and 33.3 C) decreased (P less than or equal to .05) albumen and shell weight; yolk weight was depressed only at 33.3 C. The use of wet feed (50% moisture), ad libitum, or in the p.m. stimulated DM intake at 33.3 C.

A new in-cage treatment system for control of northern fowl mites on laying hens.

Commercially available plastic and other types of flexible tubing were tested to determine their relative permeability to an emulsifiable concentrate (EC) of permethrin acaricide. Bioassays employing northern fowl mites, Ornithonyssus sylviarum (Canestrini and Fanzago), indicated that .3 mg permethrin/cm2 surface area penetrated vinyl plastic tubing that had been filled with 42.5% active ingredient EC for 14 days. Vinyl tubing circuits were installed in wire poultry cages, either in the form of suspended loops or woven through the rear cage wall, and permethrin EC was introduced by means of a small pump. Significant reductions in northern fowl mite populations on hens caged therein were apparent after 48 days posttreatment. This approach has merit as a long-term, labor-economical form of mite control on caged poultry.

Comparative efficacy of plastic strips impregnated with permethrin and permethrin dust for northern fowl mite control on caged laying hens.

Established populations of northern fowl mites, Ornitonyssus sylviarum (Canestrini and Fanzago), on caged laying hens were effectively controlled within 77 days by application of two plastic strips impregnated with permethrin per cage. Such strips contained 9.6% active ingredient (wt/wt), were ca. 20.5-cm long, and were affixed to the top cage wires. Use of only one strip per cage resulted in less control, approximating that obtained with .25% permethrin dust. Egg mass, expressed as gram egg per hen per day, was significantly greater in all treated groups.

Comparative evaluation of four registered acaricides for field control of northern fowl mites on caged laying hens.

Carbaryl and tetrachlorvinphos provided longer lasting control of northern fowl mites, Ornithonyssus sylviarum (Canestrini and Fanzago), than did coumaphos or malathion when the materials were applied to caged laying hens as aqueous sprays. The average duration of residual control was ca. 5 weeks for carbaryl, 4.3 weeks for tetrachlorvinphos, 3.5 weeks for coumaphos, and 2 weeks for malathion. No presumptive evidence of northern fowl mite resistance to carbaryl or tetrachlorvinphos was encountered. In contrast, malathion often failed to produce satisfactory control, and difficulty with adequate dispersion of coumaphos wettable powder was noted.

The encoding of ignored information.

An experiment was conducted to study the dimensions of encoding of verbal material in short-term memory as a function of other demands placed on Ss attention. Eighty Ss shadowed one of two simultaneous lists, under instructions to remember the shadowed or the nonshadowed list, A single recognition probe followed each shadowing trial. Ss judged whether the probed item was (1) identical to, (2) a rhyme of, or (3) a synonym of one of the to be remembered items. Results indicated that acoustic information was encoded from all inputs, regardless of the focus of attention. Evidence for semantic encoding, however, was limited to those conditions in which retention of shadowed material was required. The data were interpreted as contradicting "late selection" theories of attention, which propose that all inputs are analyzed for meaning prior to the focusing of attention.