Development of a Predictive Model for the Diagnosis of Lower Urinary Tract Obstruction in Men.

PURPOSE: We sought to develop and validate a bladder outlet obstruction predictive model for men with nonneurogenic lower urinary tract symptoms. MATERIALS AND METHODS: We retrospectively included 1,148 patients who underwent a urodynamic study in the Urology Service of the Burgos University Hospital from January 2007 to December 2019. Obstruction was defined using the Abrams-Griffiths number. A multivariable logistic regression analysis was conducted to determine the predictors of bladder outlet obstruction. We transferred these data to a model to calculate the individual probability of obstruction. RESULTS: A first group with 563 patients randomly divided was selected for the design of the predictive risk model and a second group of 585 patients for the validation. A total of 331 patients (58.8%) in the development group and 381 (65.1%) in the validation group had a diagnosis of obstruction. A multivariable logistic regression model showed that age, history of previous surgical intervention, presence of voiding symptoms, preserved anal tone, maximum urinary flow rate and voiding efficiency were significant for predicting obstruction. The model had an area under the receiver operating characteristic curve of 0.78 (95% CI 0.75-0.82) and a model validation of 0.78 (0.72-0.83). CONCLUSIONS: Our proposed model based on clinical and noninvasive urodynamics parameters allows us to predict the risk of presenting bladder outlet obstruction in patients with lower urinary tract symptoms.

X-ray line polarization of He-like Si satellite spectra in plasmas driven by high-intensity ultrashort pulsed lasers.

We present a modeling study of x-ray line polarization in plasmas driven by high-intensity, ultrashort duration pulsed lasers. Electron kinetics simulations of these transient and nonequilibrium plasmas predict non-Maxwellian and anisotropic electron distribution functions. Under these conditions, the magnetic sublevels within fine structure levels can be unequally populated which leads to the emission of polarized lines. We have developed a time-dependent, collisional-radiative atomic kinetics model of magnetic sublevels to understand the underlying processes and mechanisms leading to the formation of polarized x-ray line emission in plasmas with anisotropic electron distribution functions. The electron distribution function consists of a thermal component extracted from hydrodynamic calculations and a beam component determined by PIC simulations of the laser-plasma interaction. We focus on the polarization properties of the He-like Si satellites of the L y(alpha) line, discuss the time evolution of polarized satellite spectra, and identify suitable polarization markers that are sensitive to the anisotropy of the electron distribution function and can be used for diagnostic applications.

Endometriosis ureteral / Ureteral endometriosis

OBJETIVOS: Destacar que la endometriosis ureteral es una patología infrecuente en la práctica urológica, con un diagnóstico tardío y que de forma silente puede provocar el deterioro irreversible del tramo urinario superior en el que asienta. MÉTODOS Y RESULTADOS: Presentamos un caso de endometriosis ureteral unilateral que precisó de un tratamiento quirúrgico agresivo tras haber dado una oportunidad a la terapéutica hormonal y endourológica. CONCLUSIONES: El diagnóstico de endometriosis ureteral debe considerarse en mujeres que se presentan con obstrucción renal no litiásica, especialmente en mujeres premenopáusicas con nula o escasa descendencia o con cirugía pelviana previa. Sólo con un alto índice de sospecha y la instrumentación radiológica se puede contribuir a reducir el número alarmante de nefrectomías que lleva asociadas (AU)