Comparative analysis of biomechanical characteristics between the new Tai Chi elastic band exercise for opening and closing movement and elastic band resistance training for the reverse fly movement.

Background: The objective of this study was to compare and analyze the representative opening and closing movement of Tai Chi elastic band exercise with the reverse fly movement of elastic band resistance training. The aim was to explore the biomechanical differences between the two exercises and provide theoretical support for the application of Tai Chi elastic band exercise in health intervention. Methods: A total of 26 male participants were recruited and randomly divided into two groups in a 1:1 ratio. There were 13 participants in each Tai Chi elastic band exercise group and elastic band resistance training group. Both groups of participants used an elastic band to perform movement in the experiment. Experimental data were collected using the Vicon infrared motion capture system and Delsys surface EMG system. The AnyBody software was utilized to simulate the creation of a musculoskeletal model for both exercises. Result: The study found that the Tai Chi elastic band exercise group exhibited smaller horizontal abduction angle and flexion angle of the shoulder joint, as well as normalized RMS of the anterior deltoid and triceps brachii, compared to the elastic band resistance training group (P < 0.01); the Tai Chi elastic band exercise group exhibited greater elbow flexion angle, elbow flexion torque, and muscle strength of the infraspinatus, coracobrachialis, biceps brachii, brachialis and brachioradialis, compared to the elastic band resistance training group (P < 0.01); the Tai Chi elastic band exercise group exhibited smaller horizontal abduction angular velocity of the shoulder joint and a lower normalized RMS of the posterior deltoid, compared to the elastic band resistance training group (P < 0.05). Conclusion: (1) The opening and closing movement of Tai Chi elastic band exercise is characterized by a large elbow flexion angle, a small shoulder joint horizontal angle and flexion angle, and a slow and uniform speed of movement. The reverse fly movement of elastic band resistance training is characterized by a large horizontal abduction angle of the shoulder joint, a large flexion angle of the shoulder joint, a small flexion angle of the elbow joint, and a fast and uneven speed. (2) The opening and closing movement exerts a greater torque on the elbow flexion, while the reverse fly movement exerts a greater torque on the shoulder joint horizontal abduction and external rotation. (3) The opening and closing movement provide greater stimulation to the infraspinatus, coracobrachialis, and elbow flexor, while the reverse fly movement provides greater stimulation to the posterior deltoid, anterior deltoid, subscapularis, and elbow extensor. In summary, the variation in joint angle, joint angular velocity, and hand position could be the factor contributing to the differences in joint torque and muscle activity between the opening and closing movement of Tai Chi elastic band exercise and the reverse fly movement of elastic band resistance training.

A cobalt-modified covalent organic framework enables highly efficient degradation of 2,4-dichlorophenol in high concentrations through peroxymonosulfate activation.

The development of covalent organic frameworks (COFs) which can rapidly degrade high concentrations of 2,4-dichlorophenol is of great significance for its practical application. In this work, we report a cobalt-doped two-dimensional (2D) COF (JLNU-307-Co) for the ultra-efficient degradation of high concentration 2,4-dichlorophenol (2,4-DCP) by activating peroxymonosulfate (PMS). The JLNU-307-Co/PMS system takes only 3 min to degrade 100% of 50 mg L-1 2,4-DCP and shows excellent catalytic stability in real water. The superoxide radical (O2˙-) and singlet oxygen (1O2) play a major role in the system through capture experiments and electron spin resonance (ESR) tests. Compared to most previously reported catalysts, JLNU-307-Co/PMS showed the highest efficiency to date in degrading 2,4-DCP. This work not only demonstrates the potential of COFs as a catalyst for water environmental treatment, but also provides unprecedented insights into the degradation of organic pollutants.

Design of Three-Dimensional Mesoporous Adamantane-Based Covalent Organic Framework with Exceptionally High Surface Areas.

The development of three-dimensional (3D) covalent organic frameworks (COFs) with large pores and high specific surface areas is of critical for practical applications. However, it remains a tremendous challenge to reconcile the contradiction between high porosity and high specific surface areas, and increasing the length of building blocks leads to structural interpenetration in 3D COFs. Here, we report the preparation of mesoporous three-dimensional COF by a new steric hindrance engineering method. By incorporating adamantane into the monomers instead of carbon centers, we successfully achieve 2-fold interpenetrated diamondoid-structured 3D COFs, featuring permanent mesopores (up to 33 Å), exceptionally high surface areas (>3400 m2 g-1), and low crystal densities (0.123 g cm-3). These properties far surpass those of most conventional 3D COFs with similar topologies. This work not only aims to construct 3D COFs with low interpenetration but also to establish a foundation for the systematic design and structural control of 3D COFs.

A Study of the Effects of Motor Experience on Neuromuscular Control Strategies During Sprint Starts.

Much of the current research on sprint start has attempted to analyze the biomechanical characteristics of elite athletes to provide guidance on the training of sprint technique, with less attention paid to the effects of motor experience gained from long-term training on neuromuscular control characteristics. The present study attempted to investigate the effect of motor experience on the modular organization of the neuromuscular system during starting, based on he clarification of the characteristics of muscle synergies during starting. It was found that exercise experience did not promote an increase in the number of synergies but rather a more focused timing of the activation of each synergy, allowing athletes to quickly complete the postural transition from crouching to running during the starting.

The effect of motor experience on knee stability and inter-joint coordination when cutting at different angles.

BACKGROUND: Most studies on cutting have focused on the biomechanics of the knee and lower-limb muscle activation characteristics, with less consideration given to the influence of motor experience on control strategies at the joint level. This study aimed to investigate the differences in knee stability and inter-joint coordination between high- and low-level athletes when cutting at different angles. METHODS: A Vicon motion capture system and a Kistler force table were used to obtain kinematic and ground reaction force data during cutting. Joint dynamic stiffness and vector coding were used to assess knee stability and inter-joint coordination. Uncontrolled manifold analysis was used to clarify whether there was synergy among lower-limb joints to maintain postural stability during cutting. RESULTS: During the load acceptance phase, skilled subjects had the smallest joint stiffness at 90° compared with novice subjects (P < 0.05). Compared with novice subjects, skilled subjects had smaller knee-hip ellipse areas at 90° and 135° (P < 0.05), but larger knee-ankle ellipse areas at 135° (P < 0.05). The synergy index in load acceptance was significantly higher (P < 0.05) for skilled subjects at 90° and 135°. CONCLUSIONS: Advanced subjects can adjust joint control strategies to adapt to the demands of large-angle cutting on the change of direction. Advanced subjects can reduce knee stability for greater flexibility during cutting compared with novice subjects. By increasing the degree of synergy among the lower-limb joints, advanced athletes can maintain high postural stability.

BP neural network-based analysis of the applicability of NMF in side-step cutting.

Background: Although the spatio-temporal structure of muscle activation in cutting have been studied extensively, including time-varying motor primitives and time-invariant motor modules under various conditions, the factorisation methods suitable for cutting are unclear, and the extent to which each factorisation method loses information about movement during dimensionality reduction is uncertain. Research question: To clarify the extent to which NMF, PCA and ICA retain information about movement when downscaling, and to explore the factorisation method suitable for cutting. Methods: The kinematic data during cutting was captured with a Vicon motion capture system, from which the kinematic features of the pelvic centre of mass were calculated. NMF, PCA and ICA were used to obtain muscle synergies based on sEMG of the cutting at different angles, respectively. A back propagation neural network was constructed using temporal component of synergy as input and the kinematics data of pelvic as output. Calculation of the Hurst index using fractal analysis based on the temporal component of muscle synergy. Results: The quality of sEMG reconstruction is significantly higher with ICA (P < 0.01) than with NMF and PCA for the cutting. The NMF reconstruction has a high degree of preservation of movement, whereas the ICA loses movement information about the most of the swing phase, and the PCA loses information related to the change of direction. Hurst index less than 0.5 for all three angles of cutting. Significance: NMF is suitable for extracting muscle synergies in all directions of cutting. Information related to movement may be lost when using PCA and ICA to extract the synergy of cutting. The high individual variability of muscle synergy in cutting may be responsible for the loss of movement information in muscle synergy.

An analysis of the effect of motor experience on muscle synergy in the badminton jump smash.

The jump smash is badminton's most aggressive technical manoeuvre, which is often the key to winning a match. This paper aims to explore the neuromuscular control strategies of advanced and beginner players when jumping smash in different ways. Collecting sEMG and kinematic data from 18 subjects with different motor experiences when jumping smash. Nonnegative Matrix Factorization and K-Means clustering were used to extract muscle synergies and exclude irrelevant combined synergies. Uncontrolled manifold analysis was then used to explore the association between synergies and shoulder stability. In addition, motor output at the spinal cord level was assessed by mapping sEMG to each spinal cord segment. The study found that advanced subjects could respond to different jump smash styles by adjusting the coordinated activation strategies of the upper-limb and postural muscles. Long-term training can induce a rapid decrease in the degree of co-variation of the synergies before contact with a shuttlecock to better cope with an upcoming collision. It is recommended that beginners should focus more on training the coordination of upper-limb muscles and postural muscles.

A Study of Racket Weight Adaptation in Advanced and Beginner Badminton Players.

The jump smash is the most aggressive manoeuvre in badminton. Racket parameters may be the key factor affecting the performance of jump smash. Previous studies have focused only on the biomechanical characteristics of athletes or on racket parameters in isolation, with less observation of the overall performance of the human-racket system. This study aims to explore the effects of different racket weights on neuromuscular control strategies in advanced and beginner players. Nonnegative matrix factorisation (NMF) was used to extract the muscle synergies of players when jumping smash using different rackets (3U, 5U), and K-means clustering was used to obtain the fundamental synergies. Uncontrolled manifold (UCM) analyses were used to establish links between synergy and motor performance, and surface electromyography (sEMG) was mapped to each spinal cord segment. The study found significant differences (P < 0.05) in the postural muscles of skilled players and significant differences (P < 0.001) in the upper-limb muscles of beginners when the racket weight was increased. Advanced players adapt to the increase in racket weight primarily by adjusting the timing of the activation of the third synergy. Combined synergy in advanced players is mainly focused on the backswing, while that in beginners is mainly focused on the frontswing. This suggests that advanced players may be more adept at utilising the postural muscles and their coordination with the upper-limb muscles to adapt to different rackets. In addition, the motor experience can help athletes adapt more quickly to heavier rackets, and this adaptation occurs primarily by adjusting the temporal phase and covariation characteristics of the synergies rather than by increasing the number of synergies.

Iron-decorated covalent organic framework as efficient catalyst for activating peroxydisulfate to degrade 2,4-dichlorophenol: Performance and mechanism insight.

Herein, a novel two-dimensional double-pore covalent organic framework (JLNU-305) was synthesized using N,N,N',N'-tetrakis(4-aminophenyl)-1,4-phenylenediamine (TAPD) and 2,2'-bipyridine-5,5'-dicarboxaldehyde (BPDA). The extended π-π conjugated structure and nitrogen-riched pyridine in JLNU-305 (JLNU = Jilin Normal University) provide abundant binding sites for Fe doping. The obtained JLNU-305-Fe exhibited high and recycled catalytic efficiency for peroxydisulfate (PDS) activation to completely degrade 10 mg/L 2,4-dichlorophenol (2,4-DCP) within 8 min. The JLNU-305-Fe/PDS system showed excellent catalytic activity and cyclic stability. The capture experiments and electron paramagnetic resonance (ESR) analysis indicated that the catalytic behavior of JLNU-305-Fe/PDS is contributed to the synergistic effect between free radicals and non-free radicals. It is the first time to activate PDS for covalent organic frameworks (COFs) being used to degrade 2,4-DCP, which has a great potential for development and practical application in related water environment remediation.

Characteristics of muscle synergy and anticipatory synergy adjustments strategy when cutting in different angles.

BACKGROUND: Cutting is a quick change of direction that challenges body balance and stability. As the cut-angle increases, the elite athlete can achieve higher performance by pre-adjusting the posture of the lower limb joints. However, it is unclear how the cut-angle affects the neuromuscular control of cutting and the step before cutting, which is essential for daily training and preventing injury in large-angle cutting. RESEARCH QUESTION: The purpose of this study was to determine how neuromuscular control strategies change under different angles for cutting and the step before cutting METHODS: Non-negative matrix factorisation and K-means clustering were used to extract muscle synergy in the trunk and lower limbs of 12 athletes when cutting at different angles. Uncontrolled manifold analysis was used to clarify whether the muscle synergy fluctuations in the step before cutting were beneficial in stabilising the COP during the cutting. RESULTS: This study found that the angle did not affect the number of muscle synergies either in the cutting or the step before the cutting. As the angle increases, the activation timing of synergy module 2 during cutting moves forward and is tightly integrated with module 1. The combined synergy at 90° accounted for the largest proportion of either cutting or the step before cutting and had a lower synergy index. SIGNIFICANCE: Muscle synergy can respond to large-angle cutting through flexible combinations. The muscle synergy for 90° cutting is less regular and has a lower degree of anticipatory synergy adjustments, which may result in poorer postural stability and an increased risk of lower limb joint injury during cutting.

Ultralow ruthenium modification of cobalt metal-organic frameworks for enhanced efficient bifunctional water splitting.

Hydrogen economy has emerged as a promising alternative to the current hydrocarbon economy. It involves harvesting renewable energy to split water into hydrogen and oxygen and then further utilising clean hydrogen fuel for various applications. The rational exploration of advanced non-precious metal bifunctional electrocatalysts for the oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) is critical for efficient water splitting. Herein, an ultralow Ru-modified cobalt metal-organic framework (CoRu0.06-MOF/NF) two-dimensional nanosheet array bifunctional catalyst was fabricated through a strategy under mild experimental conditions. The obtained CoRu0.06-MOF/NF exhibited excellent bifunctional electrocatalytic activity and stability in alkaline media, with low overpotentials of 37 and 181 mV and significant durability for more than 95 and 110 h toward the HER and OER at 10 mA cm-2, respectively. The experimental results showed that the two-dimensional nanoarray structure had a large specific surface area and abundant exposed active sites. Additionally, ultralow Ru modification optimized the electronic structure and improved the conductivity of the cobalt metal-organic frameworks, thereby reducing the energy barrier of the rate-limiting step and accelerating the water splitting reaction.

A long short-term memory modeling-based compensation method for muscle synergy.

Muscle synergy containing temporal and spatial patterns of muscle activity has been frequently used in prediction of kinematic characteristics. However, there is often some discrepancy between the predicted results based on muscle synergy and the actual movement performance. This study aims to propose a new method for compensating muscle synergy that allows the compensated synergy signal to predict kinematic characteristics more accurately. The study used the change of direction in running as background. Non-negative matrix factorisation was used to extract the muscle synergy during the change of direction at different angles. A non-linear association between synergy and the height of pelvic mass centre was established using long and short-term memory neural networks. Based on this model, the height fluctuations of the pelvic centre of mass are used as input and predict the fluctuations of the synergy which were used to compensate for the original synergy in different ways. The accuracy of the synergies compensated in different ways in predicting pelvic centre of mass movement was then assessed by back propagation neural networks. It was found that the compensated synergy significantly improves accuracy in predicting pelvic centre of mass displacement (R2, p < 0.05). The predicted results of all-compensation are significantly different from actual performance in the end-swing (p < 0.05). The predicted results of half-compensation do not differ significantly from the actual performance, and its damage to the original synergy is smaller and does not increase with angle compared to all-compensation. The all-compensation may be affected by individual variability and lead to increased errors. The half-compensation can improve the predictive accuracy of the synergy while reducing the adjustment to the original synergy.

The Influence of Experience on Neuromuscular Control of the Body When Cutting at Different Angles.

Cutting is an offensive technique commonly used in football and basketball to pass the opponent's defence by changing direction quickly in running. This paper aims to investigate the effect of experience and angle on the neuromuscular control strategies of the trunk and lower limbs during cutting. Non-negative matrix factorisation and K-means were used to extract muscle synergies (muscles that are activated in parallel) of 12 subjects with cut experience and 9 subjects without experience based on the sEMG signal collected from cutting at three cut angles (45°, 90°, and 135°), which was also mapped into the spinal motor output. Uncontrolled manifold analysis was used to establish the relationship between muscle synergies and COP. This study found that experienced subjects tended to use the lower limb muscles rather than the postural muscles as stabiliser muscles compared to novices. Experienced subjects can recruit an additional set of muscle synergy to cope with large-angle cuts. In addition, experienced subjects can activate the second muscle synergy, involving the hip and ankle stabilisation muscles, in advance to improve postural stability when cutting in large-angle. Synergy index of experienced subjects dropped rapidly before the quick stop and was relatively high during the change of direction. These results suggest that experience can modify the postural stabilisation mechanisms during cutting, and prompt the lower limb muscle synergy to produce anticipatory adjustment to improve postural stability in the anterior-posterior and internal-external directions.

In situ synthesis of morphology-controlled MoOx/Fe1-xS bifunctional catalysts for high-efficiency and stable alkaline water splitting.

The advancement of a bifunctional electrocatalyst consisting of Earth's rich elements and exhibiting high efficiency is the key to obtain hydrogen fuel by overall water splitting (OWS). Here, a facile and extensible hydrothermal synthesis of an electrocatalyst on iron foam (MoOx/Fe1-xS/IF) as a robust bifunctional catalyst with excellent catalytic activity is designed for the hydrogen evolution reaction (HER) with an overpotential of 142 mV at 100 mA cm-2, and for the OER with lower overpotentials of 300 and 500 mV at 100 and 1000 mA cm-2. The good activity is ascribed to the controllable morphology, stronger bonding of the catalyst to a substrate and optimized electronic configuration. When used as bifunctional electrocatalysts toward alkaline overall water splitting, MoOx/Fe1-xS/IF delivers a current density of 10 mA cm-2 at a low cell voltage of 1.56 V for 110 h. Such high performance coupled with low-cost iron-based materials suggests that the present strategy may open new avenues for the rational design of electrocatalysts and for use in practical water splitting.

Three-Dimensional Chemically Stable Covalent Organic Frameworks through Hydrophobic Engineering.

The development of three-dimensional (3D) covalent organic frameworks (COFs) with high chemical stability is of critical importance for their practical use. In this work, it is demonstrated that the stability of 3D COFs can be improved by periodic decoration of isopropyl groups on their backbones. Owing to the strong hydrophobicity of the alkyl groups, the resultant COFs show high crystallinity, permanent pores, and exceptional stability in harsh environments, such as strong acids (3 m HCl or 3 m H2 SO4 for one week), a strong base (20 m NaOH for one week), and boiling water (100 °C for one month). Furthermore, these highly stable and hydrophobic COFs display excellent oil/water separation performance with >99 % separation efficiency over a wide pH range. This work demonstrates the use of alkyl decoration in 3D COFs to tune their chemical stability and expand their potential applications.

Chemically stable polyarylether-based covalent organic frameworks.

The development of crystalline porous materials with high chemical stability is of paramount importance for their practical application. Here, we report the synthesis of polyarylether-based covalent organic frameworks (PAE-COFs) with high crystallinity, porosity and chemical stability, including towards water, owing to the inert nature of their polyarylether-based building blocks. The PAE-COFs are synthesized through nucleophilic aromatic substitution reactions between ortho-difluoro benzene and catechol building units, which form ether linkages. The resulting materials are shown to be stable against harsh chemical environments including boiling water, strong acids and bases, and oxidation and reduction conditions. Their stability surpasses the performance of other known crystalline porous materials such as zeolites, metal-organic frameworks and covalent organic frameworks. We also demonstrate the post-synthetic functionalization of these materials with carboxyl or amino functional groups. The functionalized PAE-COFs combine porosity, high stability and recyclability. A preliminary application of these materials is demonstrated with the removal of antibiotics from water over a wide pH range.

One-pot cascade syntheses of microporous and mesoporous pyrazine-linked covalent organic frameworks as Lewis-acid catalysts.

Covalent organic frameworks (COFs) are crystalline porous solids with broad potential applications. So far, the successful construction of COFs has been limited to a few condensation reactions, and nearly all COFs were obtained by single-step synthesis based on predesigned linkers. Here, we report a general strategy in view of a one-pot cascade reaction to prepare both microporous and mesoporous fully π-conjugated pyrazine-linked COF materials (PZ-COFs). The obtained PZ-COFs show high chemical stability, large specific surface areas and promising H2, CH4 and CO2 uptake capacities. Furthermore, we demonstrate that manganese(ii)-incorporated PZ-COFs can act as excellent Lewis-acid catalysts for the cyanosilylation of aromatic aldehydes. This study not only provides a facile method to synthesize COFs required for multistep reactions but also expands the applications of COFs as promising catalysts.

Duplicate US1 Genes of Duck Enteritis Virus Encode a Non-essential Immediate Early Protein Localized to the Nucleus.

The duplicate US1 genes of duck enteritis virus (DEV) encode a protein with a conserved Herpes_IE68 domain, which was found to be closely related to the herpes virus immediate early regulatory protein family and is highly conserved among counterparts encoded by Herpes_IE68 genes. Previous studies found the homologous proteins HSV-1 ICP22 and VZV ORF63/ORF70 to be critical for virus transcription and replication. However, little is known about the DEV ICP22 protein. In this paper, we describe the characteristics of this protein based on pharmacological experiments, real-time quantitative Polymerase Chain Reaction, Western blot, and immunofluorescence assays. We also investigate the role of the protein in DEV replication via mutation of US1. As a result, we found that the DEV ICP22 protein is a non-essential immediate early protein predominantly located in the nucleus of infected DEF cells and that DEV replication is impaired by US1 deletion. We also found that ICP22 contains a classical nuclear localization signal (NLS) at 305-312AA, and ICP22 cannot enter the nucleus by itself after mutating residue 309.

US10 Protein Is Crucial but not Indispensable for Duck Enteritis Virus Infection in Vitro.

To investigate the function of the duck enteritis virus (DEV) tegument protein US10, we generated US10 deletion and revertant mutants (ΔUS10 and US10FRT) via two-step RED recombination based on an infectious BAC clone of DEV CHv-BAC-G (BAC-G). In multistep growth kinetic analyses, ΔUS10 showed an approximately 100-fold reduction in viral titer, while the genome copies decreased only 4-fold compared to those of BAC-G. In one-step growth kinetic analyses, there were no significant differences in genome copies among BAC-G, ΔUS10 and US10FRT, but ΔUS10 still showed a 5- to 20-fold reduction in viral titer, and the replication defect of ΔUS10 was partially reversed by infection of US10-expressing cells. The transcription levels of Mx, OASL, IL-4, IL-6 and IL-10 in ΔUS10-infected duck embryo fibroblasts (DEFs) were significantly upregulated, while TLR3 was downregulated compared with those in BAC-G-infected DEFs. Taken together, these data indicated that US10 is vital for DEV replication and is associated with transcription of some immunity genes.

Transcriptomic Characterization of a Chicken Embryo Model Infected With Duck Hepatitis A Virus Type 1.

Duck hepatitis A virus type 1 (DHAV-1) is one of the most common and lethal pathogens in young ducklings. Live-attenuated DHAV vaccine (CH60 strain) developed by passaging in chicken embryos provided effective immune protection for ducklings. However, the accurate mechanism for such adaption in chicken embryos is not fully revealed. Here, we utilize RNA-sequencing to perform global transcriptional analysis of DHAV-1-innoculated embryonated livers along with histopathological and ultrastructural analysis. This study revealed that infection with DHAV-1 strain CH60 is associated with enhanced type I and II interferon responses, activated innate immune responses, elevated levels of suppressor of cytokine signaling 1 and 3 (SOCS1 and SOCS3) accompanied with abnormalities in multiple metabolic pathways. Excessive inflammatory and innate immune responses induced by the CH60 strain are related to severe liver damage. Our study presents a comprehensive characterization of the transcriptome of chicken embryos infected with DHAV-CH60 and provides insight for in-depth exploration of viral adaption and virus-host interactions.