1.
Bioorg Med Chem Lett
; 9(11): 1587-92, 1999 Jun 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10386941
RESUMO
The title compound 1 is a potent interleukin-1beta-converting enzyme (ICE) inhibitor. Recently, an efficient chiral synthesis of compound 1 has been accomplished in our labs. The overall yield of this 18-step stereoselective synthesis was 9.8%.