RESUMO
This study evaluated the BHIA screening method with 4 or 6 mug/mL of vancomycin to detect glycopeptides heteroresistant staphylococci strains isolated from bacteremia. A total of 213 staphylococci strains were isolated from 106 patients between October/2001 and November/2002 in a tertiary hospital in Rio de Janeiro city. Fifty-seven (53.8%) patients presented Staphylococcus aureus, while coagulase-negative staphylococci (CNS) were isolated from 49 (46.2%). Resistance rates for oxacillin of 26.3% and 81.6% were found for the staphylococci isolates, respectively. Thirteen CNS isolated from nine (8.5%) patients grew on agar screening with 4 mug/mL of vancomycin and showed heterogeneous profiles of resistance for vancomycin and teicoplanin by the population analysis profile method. Only 30.8% of them grew at the concentration 6 mug/mL. Bacterial infection and use of antimicrobial therapy were common among these patients. Alert about the emergence of oxacillin-resistant staphylococci presenting heteroresistance to glycopeptides is important in order to achieve judicious use of antimicrobials. Vancomycin agar screening test could help to confirm the presence of these isolates in hospitals.
Assuntos
Antibacterianos/farmacologia , Staphylococcus/efeitos dos fármacos , Teicoplanina/farmacologia , Vancomicina/farmacologia , Idoso , Idoso de 80 Anos ou mais , Bacteriemia/microbiologia , Meios de Cultura , Feminino , Humanos , Lactente , Masculino , Testes de Sensibilidade Microbiana/métodos , Reprodutibilidade dos Testes , Infecções Estafilocócicas/microbiologia , Staphylococcus/classificação , Staphylococcus/isolamento & purificaçãoRESUMO
This study evaluated the BHIA screening method with 4 or 6 mug/mL of vancomycin to detect glycopeptides heteroresistant staphylococci strains isolated from bacteremia. A total of 213 staphylococci strains were isolated from 106 patients between October/2001 and November/2002 in a tertiary hospital in Rio de Janeiro city. Fifty-seven (53.8 percent) patients presented Staphylococcus aureus, while coagulase-negative staphylococci (CNS) were isolated from 49 (46.2 percent). Resistance rates for oxacillin of 26.3 percent and 81.6 percent were found for the staphylococci isolates, respectively. Thirteen CNS isolated from nine (8.5 percent) patients grew on agar screening with 4 mug/mL of vancomycin and showed heterogeneous profiles of resistance for vancomycin and teicoplanin by the population analysis profile method. Only 30.8 percent of them grew at the concentration 6 mug/mL. Bacterial infection and use of antimicrobial therapy were common among these patients. Alert about the emergence of oxacillin-resistant staphylococci presenting heteroresistance to glycopeptides is important in order to achieve judicious use of antimicrobials. Vancomycin agar screening test could help to confirm the presence of these isolates in hospitals.
Assuntos
Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Lactente , Masculino , Antibacterianos/farmacologia , Staphylococcus/efeitos dos fármacos , Teicoplanina/farmacologia , Vancomicina/farmacologia , Bacteriemia/microbiologia , Meios de Cultura , Testes de Sensibilidade Microbiana/métodos , Reprodutibilidade dos Testes , Infecções Estafilocócicas/microbiologia , Staphylococcus/classificação , Staphylococcus/isolamento & purificaçãoRESUMO
Este estudo avaliou percepções e atitudes em saúde bucal de 169 responsáveis por crianças portadoras ou não de necessidades especiais (31,0 meses ± 14,4) de uma instituição pública do Rio de Janeiro. Somente 17,9 por cento da amostra respondeu corretamente sobre como a saúde bucal pode interferir na saúde geral. No entanto, a higiene bucal foi apontada pela maioria como principal método de prevenção da cárie. Das crianças que já visitaram o cirugião-dentista, 94,4 por cento têm quem escove seus dentes. Este valor é de 73,4 por cento para as que nunca visitaram um dentista (p-valor=0,0002). Conclui-se que os conhecimentos e atitudes em saúde bucal não foram satisfatórios
