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Clin Transl Oncol ; 18(5): 533-6, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-26307754

RESUMO

PURPOSE: Survival rates among patients with lymphoma continue to improve. Strategies aimed at reducing potential treatment-related toxicity are increasingly prioritized. While radiological procedures play an important role, ionizing radiation exposure has been linked to an increased risk of malignancy, particularly among individuals whose cumulative radiation exposure exceeds a specific threshold (75 millisieverts). METHODS: Within this retrospective study, the cumulative radiation exposure dose was quantified for 486 consecutive patients with lymphoma. RESULTS: The median estimated total cumulative effective dose (CED) of ionizing radiation per subject was 69 mSv (42-118). However, younger patients (under 40 years) had a median CED of 89 mSv (55-124). CONCLUSION: This study highlights the considerable radiation exposure occurring among patients with lymphoma as a result of diagnostic imaging. To limit the risk of secondary carcinogenesis, consideration should be given to monitoring cumulative radiation exposure in individual patients as well as considering imaging modalities, which do not impart an ionizing radiation dose.


Assuntos
Diagnóstico por Imagem/efeitos adversos , Linfoma/diagnóstico por imagem , Neoplasias Induzidas por Radiação/etiologia , Radiação Ionizante , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Seguimentos , Humanos , Linfoma/complicações , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Neoplasias Induzidas por Radiação/patologia , Tomografia por Emissão de Pósitrons , Prognóstico , Estudos Prospectivos , Doses de Radiação , Estudos Retrospectivos , Tomografia Computadorizada por Raios X
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