RESUMO
Neurofibromatosis type-1 (NF-1)--is a common genetic disease effecting the skin, subcutaneous tissue peripheral nerves and bones (tibia pseudarthrosis). Immunomodulatory viruses HHV-6 and HHV-7 are classifying as a genus of roseoloviruses of subfamily beta-herpesviruses. Reactivation of HHV-6 and HHV-7 inhibits immune system and indirectly promote to other infectious agents. The article deals with a unique case repot of two repeated transplantations of fibula due to congenital tibia pseudarthrosis caused by NF-1. Results of the transplantations, related to active and latent HHV-6 and HHV-7 infection in a 6 years old child are discussed in the paper.
Assuntos
Herpesvirus Humano 6/isolamento & purificação , Herpesvirus Humano 7/isolamento & purificação , Deformidades Congênitas das Extremidades Inferiores/cirurgia , Pseudoartrose/cirurgia , Infecções por Roseolovirus/complicações , Tíbia/cirurgia , Pré-Escolar , Humanos , Deformidades Congênitas das Extremidades Inferiores/complicações , Deformidades Congênitas das Extremidades Inferiores/imunologia , Deformidades Congênitas das Extremidades Inferiores/virologia , Masculino , Pseudoartrose/complicações , Pseudoartrose/imunologia , Pseudoartrose/virologia , Reoperação , Infecções por Roseolovirus/imunologia , Infecções por Roseolovirus/virologia , Tíbia/imunologia , Tíbia/virologia , Falha de Tratamento , Resultado do TratamentoRESUMO
The aim of the study was to evaluate the use of cuffed oropharyngeal airway (COPA) in spontaneously breathing patients (n = 162) under total anesthesia and to compare the new method with the laryngeal mask (LM) (n = 172). COPA provided adequate well-hermetized airway in operations under total anesthesia on spontaneously breathing patients. COPA can serve as an alternative to LM in patients with spontaneous respiration, as no appreciable differences in the incidence and type of complications in the two groups were observed. COPA extends the anesthesiologist's potentialities in ensuring reliable patency of airways, is simple, and requires no special training.
Assuntos
Anestesia Geral , Intubação Intratraqueal/instrumentação , Adolescente , Adulto , Idoso , Criança , Humanos , Máscaras Laríngeas , Pessoa de Meia-Idade , RespiraçãoRESUMO
The authors discuss their clinical experience in the use of deep hypothermia in combination with auxiliary extracorporeal circulation. Operations were performed on 124 children (total mortality 23.4%). Lowest mortality was noted in correction of ventricular septal defect; 12 out of 82 patients died, which accounts for approximately 14.6%. A follow-up of the remote results shows that the method has no harmful effect on the central nervous system.