1.
Antimicrob Agents Chemother
; 47(6): 2051-5, 2003 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12760898
RESUMO
Pantothenate kinase (CoaA) catalyzes the first step of the coenzyme A biosynthetic pathway. Here we report the identification of the Staphylococcus aureus coaA gene and characterization of the enzyme. We have also identified a series of low-molecular-weight compounds which are effective inhibitors of S. aureus CoaA.