An accelerated sine mapping whale optimizer for feature selection.

An improved whale optimization algorithm (SWEWOA) is presented for global optimization issues. Firstly, the sine mapping initialization strategy (SS) is used to generate the population. Secondly, the escape energy (EE) is introduced to balance the exploration and exploitation of WOA. Finally, the wormhole search (WS) strengthens the capacity for exploitation. The hybrid design effectively reinforces the optimization capability of SWEWOA. To prove the effectiveness of the design, SWEWOA is performed in two test sets, CEC 2017 and 2022, respectively. The advantage of SWEWOA is demonstrated in 26 superior comparison algorithms. Then a new feature selection method called BSWEWOA-KELM is developed based on the binary SWEWOA and kernel extreme learning machine (KELM). To verify its performance, 8 high-performance algorithms are selected and experimentally studied in 16 public datasets of different difficulty. The test results demonstrate that SWEWOA performs excellently in selecting the most valuable features for classification problems.

Renal Pathology Images Segmentation Based on Improved Cuckoo Search with Diffusion Mechanism and Adaptive Beta-Hill Climbing.

Lupus Nephritis (LN) is a significant risk factor for morbidity and mortality in systemic lupus erythematosus, and nephropathology is still the gold standard for diagnosing LN. To assist pathologists in evaluating histopathological images of LN, a 2D Rényi entropy multi-threshold image segmentation method is proposed in this research to apply to LN images. This method is based on an improved Cuckoo Search (CS) algorithm that introduces a Diffusion Mechanism (DM) and an Adaptive ß-Hill Climbing (AßHC) strategy called the DMCS algorithm. The DMCS algorithm is tested on 30 benchmark functions of the IEEE CEC2017 dataset. In addition, the DMCS-based multi-threshold image segmentation method is also used to segment renal pathological images. Experimental results show that adding these two strategies improves the DMCS algorithm's ability to find the optimal solution. According to the three image quality evaluation metrics: PSNR, FSIM, and SSIM, the proposed image segmentation method performs well in image segmentation experiments. Our research shows that the DMCS algorithm is a helpful image segmentation method for renal pathological images.

An artificial bee bare-bone hunger games search for global optimization and high-dimensional feature selection.

The domains of contemporary medicine and biology have generated substantial high-dimensional genetic data. Identifying representative genes and decreasing the dimensionality of the data can be challenging. The goal of gene selection is to minimize computing costs and enhance classification precision. Therefore, this article designs a new wrapper gene selection algorithm named artificial bee bare-bone hunger games search (ABHGS), which is the hunger games search (HGS) integrated with an artificial bee strategy and a Gaussian bare-bone structure to address this issue. To evaluate and validate the performance of our proposed method, ABHGS is compared to HGS and a single strategy embedded in HGS, six classic algorithms, and ten advanced algorithms on the CEC 2017 functions. The experimental results demonstrate that the bABHGS outperforms the original HGS. Compared to peers, it increases classification accuracy and decreases the number of selected features, indicating its actual engineering utility in spatial search and feature selection.

Adaptive Aquila Optimizer with Explainable Artificial Intelligence-Enabled Cancer Diagnosis on Medical Imaging.

Explainable Artificial Intelligence (XAI) is a branch of AI that mainly focuses on developing systems that provide understandable and clear explanations for their decisions. In the context of cancer diagnoses on medical imaging, an XAI technology uses advanced image analysis methods like deep learning (DL) to make a diagnosis and analyze medical images, as well as provide a clear explanation for how it arrived at its diagnoses. This includes highlighting specific areas of the image that the system recognized as indicative of cancer while also providing data on the fundamental AI algorithm and decision-making process used. The objective of XAI is to provide patients and doctors with a better understanding of the system's decision-making process and to increase transparency and trust in the diagnosis method. Therefore, this study develops an Adaptive Aquila Optimizer with Explainable Artificial Intelligence Enabled Cancer Diagnosis (AAOXAI-CD) technique on Medical Imaging. The proposed AAOXAI-CD technique intends to accomplish the effectual colorectal and osteosarcoma cancer classification process. To achieve this, the AAOXAI-CD technique initially employs the Faster SqueezeNet model for feature vector generation. As well, the hyperparameter tuning of the Faster SqueezeNet model takes place with the use of the AAO algorithm. For cancer classification, the majority weighted voting ensemble model with three DL classifiers, namely recurrent neural network (RNN), gated recurrent unit (GRU), and bidirectional long short-term memory (BiLSTM). Furthermore, the AAOXAI-CD technique combines the XAI approach LIME for better understanding and explainability of the black-box method for accurate cancer detection. The simulation evaluation of the AAOXAI-CD methodology can be tested on medical cancer imaging databases, and the outcomes ensured the auspicious outcome of the AAOXAI-CD methodology than other current approaches.

Whale optimization with random contraction and Rosenbrock method for COVID-19 disease prediction.

Coronavirus Disease 2019 (COVID-19), instigated by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has hugely impacted global public health. To identify and intervene in critically ill patients early, this paper proposes an efficient, intelligent prediction model based on the machine learning approach, which combines the improved whale optimization algorithm (RRWOA) with the k-nearest neighbor (KNN) classifier. In order to improve the problem that WOA is prone to fall into local optimum, an improved version named RRWOA is proposed based on the random contraction strategy (RCS) and the Rosenbrock method. To verify the capability of the proposed algorithm, RRWOA is tested against nine classical metaheuristics, nine advanced metaheuristics, and seven well-known WOA variants based on 30 IEEE CEC2014 competition functions, respectively. The experimental results in mean, standard deviation, the Friedman test, and the Wilcoxon signed-rank test are considered, proving that RRWOA won first place on 18, 24, and 25 test functions, respectively. In addition, a binary version of the algorithm, called BRRWOA, is developed for feature selection problems. An efficient prediction model based on BRRWOA and KNN classifier is proposed and compared with seven existing binary metaheuristics based on 15 datasets of UCI repositories. The experimental results show that the proposed algorithm obtains the smallest fitness value in eleven datasets and can solve combinatorial optimization problems, indicating that it still performs well in discrete cases. More importantly, the model was compared with five other algorithms on the COVID-19 dataset. The experiment outcomes demonstrate that the model offers a scientific framework to support clinical diagnostic decision-making. Therefore, RRWOA is an effectively improved optimizer with efficient value.

A novel metaheuristics with adaptive neuro-fuzzy inference system for decision making on autonomous unmanned aerial vehicle systems.

Recently, autonomous systems have received considerable attention amongst research communities and academicians. Unmanned aerial vehicles (UAVs) find useful in several applications like transportation, surveillance, disaster management, and wildlife monitoring. One of the important issues in the UAV system is energy efficiency, which can be resolved by the use of clustering approaches. In addition, high resolution remote sensing images need to be classified for effective decision making using deep learning (DL) models. Though several models are available in the literature, only few approaches have focused on the clustering and classification processes in UAV networks. In this aspect, this paper designs a novel metaheuristic with an adaptive neuro-fuzzy inference system for decision making named MANFIS-DM technique on autonomous UAV systems. The proposed MANFIS-DM technique intends to effectively organize the UAV networks into clusters and then classify the images into appropriate class labels. The proposed MANFIS-DM technique encompasses two major stages namely quantum different evolution based clustering (QDE-C) technique and ANFIS based classification technique. Primarily, the QDE-C technique involves the design of a fitness function involving three parameters namely average distance, distance to UAVs, and UAV degree. Besides, the image classification model involves a set of subprocesses namely DenseNet based feature extraction, Adadelta based hyperparameter optimization, and ANFIS based classification. The design of QDE-C algorithm with classification model for autonomous UAV systems show the novelty of the work. The experimental result analysis of the MANFIS-DM method is carried out against benchmark dataset and the results ensured the enhanced performance of the MANFIS-DM technique over the other methods with the maximum accuy of 99.13%.

Design of cultural emperor penguin optimizer for energy-efficient resource scheduling in green cloud computing environment.

In recent times, energy related issues have become challenging with the increasing size of data centers. Energy related issues problems are becoming more and more serious with the growing size of data centers. Green cloud computing (GCC) becomes a recent computing platform which aimed to handle energy utilization in cloud data centers. Load balancing is generally employed to optimize resource usage, throughput, and delay. Aiming at the reduction of energy utilization at the data centers of GCC, this paper designs an energy efficient resource scheduling using Cultural emperor penguin optimizer (CEPO) algorithm, called EERS-CEPO in GCC environment. The proposed model is aimed to distribute work load amongst several data centers or other resources and thereby avoiding overload of individual resources. The CEPO algorithm is designed based on the fusion of cultural algorithm (CA) and emperor penguin optimizer (EPO), which boosts the exploitation capabilities of EPO algorithm using the CA, shows the novelty of the work. The EERS-CEPO algorithm has derived a fitness function to optimally schedule the resources in data centers, minimize the operational and maintenance cost of the GCC, and thereby decrease the energy utilization and heat generation. To ensure the improvised performance of the EERS-CEPO algorithm, a wide range of experiments is performed and the experimental outcomes highlighted the better performance over the recent state of art techniques.

Early and accurate detection of melanoma skin cancer using hybrid level set approach.

Digital dermoscopy is used to identify cancer in skin lesions, and sun exposure is one of the leading causes of melanoma. It is crucial to distinguish between healthy skin and malignant lesions when using computerised lesion detection and classification. Lesion segmentation influences categorization accuracy and precision. This study introduces a novel way of classifying lesions. Hair filters, gel, bubbles, and specular reflection are all options. An improved levelling method is employed in an innovative method for detecting and removing cancerous hairs. The lesion is distinguished from the surrounding skin by the adaptive sigmoidal function; this function considers the severity of localised lesions. An improved technique for identifying a lesion from surrounding tissue is proposed in the article, followed by a classifier and available features that resulted in 94.40% accuracy and 93% success. According to research, the best method for selecting features and classifications can produce more accurate predictions before and during treatment. When the recommended strategy is put to the test using the Melanoma Skin Cancer Dataset, the recommended technique outperforms the alternative.

A Framework for Interactive Medical Image Segmentation Using Optimized Swarm Intelligence with Convolutional Neural Networks.

Recent improvements in current technology have had a significant impact on a wide range of image processing applications, including medical imaging. Classification, detection, and segmentation are all important aspects of medical imaging technology. An enormous need exists for the segmentation of diagnostic images, which can be applied to a wide variety of medical research applications. It is important to develop an effective segmentation technique based on deep learning algorithms for optimal identification of regions of interest and rapid segmentation. To cover this gap, a pipeline for image segmentation using traditional Convolutional Neural Network (CNN) as well as introduced Swarm Intelligence (SI) for optimal identification of the desired area has been proposed. Fuzzy C-means (FCM), K-means, and improvisation of FCM with Particle Swarm Optimization (PSO), improvisation of K-means with PSO, improvisation of FCM with CNN, and improvisation of K-means with CNN are the six modules examined and evaluated. Experiments are carried out on various types of images such as Magnetic Resonance Imaging (MRI) for brain data analysis, dermoscopic for skin, microscopic for blood leukemia, and computed tomography (CT) scan images for lungs. After combining all of the datasets, we have constructed five subsets of data, each of which had a different number of images: 50, 100, 500, 1000, and 2000. Each of the models was executed and trained on the selected subset of the datasets. From the experimental analysis, it is observed that the performance of K-means with CNN is better than others and achieved 96.45% segmentation accuracy with an average time of 9.09 seconds.

Artificial intelligence based optimization with deep learning model for blockchain enabled intrusion detection in CPS environment.

Cyber physical system (CPS) is a network of cyber and physical elements, which interact with one another in a feedback form. CPS approves critical infrastructure and is treated as essential in day to day since it forms the basis of futuristic smart devices. An increased usage of CPSs poses security as a challenging issue and intrusion detection systems (IDS) can be applied for the identification of network intrusions. The latest advancements in the field of artificial intelligence (AI) and deep learning (DL) enables to design effective IDS models for the CPS environment. At the same time, metaheuristic algorithms can be employed as a feature selection approach in order to reduce the curse of dimensionality. With this motivation, this study develops a novel Poor and Rich Optimization with Deep Learning Model for Blockchain Enabled Intrusion Detection in CPS Environment, called PRO-DLBIDCPS technique. The proposed PRO-DLBIDCPS technique initially introduces an Adaptive Harmony Search Algorithm (AHSA) based feature selection technique for proper selection of feature subsets. For intrusion detection and classification, and attention based bi-directional gated recurrent neural network (ABi-GRNN) model is applied. In addition, the detection efficiency of the ABi-GRNN technique has been enhanced by the use of Poor and rich optimization (PRO) algorithm based hyperparameter optimizer, which resulted in enhanced intrusion detection results. Furthermore, blockchain technology is applied for enhancing security in the CPS environment. In order to demonstrate the enhanced outcomes of the PRO-DLBIDCPS technique, a wide range of simulations was carried out on benchmark dataset and the results reported the better outcomes of the PRO-DLBIDCPS technique in terms of several measures.

Directional mutation and crossover boosted ant colony optimization with application to COVID-19 X-ray image segmentation.

This paper focuses on the study of Coronavirus Disease 2019 (COVID-19) X-ray image segmentation technology. We present a new multilevel image segmentation method based on the swarm intelligence algorithm (SIA) to enhance the image segmentation of COVID-19 X-rays. This paper first introduces an improved ant colony optimization algorithm, and later details the directional crossover (DX) and directional mutation (DM) strategy, XMACO. The DX strategy improves the quality of the population search, which enhances the convergence speed of the algorithm. The DM strategy increases the diversity of the population to jump out of the local optima (LO). Furthermore, we design the image segmentation model (MIS-XMACO) by incorporating two-dimensional (2D) histograms, 2D Kapur's entropy, and a nonlocal mean strategy, and we apply this model to COVID-19 X-ray image segmentation. Benchmark function experiments based on the IEEE CEC2014 and IEEE CEC2017 function sets demonstrate that XMACO has a faster convergence speed and higher convergence accuracy than competing models, and it can avoid falling into LO. Other SIAs and image segmentation models were used to ensure the validity of the experiments. The proposed MIS-XMACO model shows more stable and superior segmentation results than other models at different threshold levels by analyzing the experimental results.

A Secure Framework toward IoMT-Assisted Data Collection, Modeling, and Classification for Intelligent Dermatology Healthcare Services.

The abnormal growth of the skin cells is known as skin cancer. It is one of the main problems in the dermatology area. Skin lesions or malignancies have been a source of worry for many individuals in recent years. Irrespective of the skin tone, there exist three major classes of skin lesions, i.e., basal cell carcinoma, squamous cell carcinoma, and melanoma. The early diagnosis of these lesions is equally important for human life. In the proposed work, a secure IoMT-Assisted framework is introduced that can help the patients to do the initial screening of skin lesions remotely. The initially proposed approach uses an IoMT-based data collection device which is accessible by patients to capture skin lesions images. Next, the captured skin sample is encrypted and sent to the collected image toward cloud storage. Later, the received sample image is classified into appropriate class labels using an ensemble classifier. In the proposed framework, four CNN models were ensemble i.e., VGG-16, DenseNet-201, Inception-V3, and Efficient-B7. The framework has experimented with the "HAM10000" dataset having 7 different kinds of skin lesions data. Although DenseNet-201 performed well, the ensemble model provides the highest accuracy with 87.22 percent as well as its test loss/error is lower than others with 0.4131. Moreover, the ensemble model's classification ability is much higher with an AUC score of 0.9745. Moreover, A recommendation team has been assigned to assess the sample of the patient as well as suggest the patient according to classified results by the CAD.

3D Input Convolutional Neural Network for SSVEP Classification in Design of Brain Computer Interface for Patient User.

This research was aimed at presenting performance of 3-dimensional input convolutional neural networks for steady-state visual evoked potential classification in a wireless EEG-based brain-computer interface system. Overall performance of a brain-computer interface system depends on information transfer rate. Parameters such as signal classification accuracy rate, signal stimulator structure, and user task completion time affect information transfer rate. In this study, we used 3 types of signal classification methods that are 1-dimensional, 2-dimensional, and 3-dimensional input convolutional neural network. According to online experiment with using 3-dimensional input convolutional neural network, we reached average classification accuracy rate and average information transfer rate as 93.75% and 58.35 bit/min, respectively. This both results significantly higher than the other methods that we used in experiments. Moreover, user task completion time was reduced with using 3-dimensional input convolutional neural network. Our proposed method is novel and state-of-art model for steady-state visual evoked potential classification.

Prediction of Diabetes through Retinal Images Using Deep Neural Network.

Microvascular problems of diabetes, such as diabetic retinopathy and macular edema, can be seen in the eye's retina, and the retinal images are being used to screen for and diagnose the illness manually. Using deep learning to automate this time-consuming process might be quite beneficial. In this paper, a deep neural network, i.e., convolutional neural network, has been proposed for predicting diabetes through retinal images. Before applying the deep neural network, the dataset is preprocessed and normalised for classification. Deep neural network is constructed by using 7 layers, 5 kernels, and ReLU activation function, and MaxPooling is implemented to combine important features. Finally, the model is implemented to classify whether the retinal image belongs to a diabetic or nondiabetic class. The parameters used for evaluating the model are accuracy, precision, recall, and F1 score. The implemented model has achieved a training accuracy of more than 95%, which is much better than the other states of the art algorithms.

Deep Transfer Learning-Based Breast Cancer Detection and Classification Model Using Photoacoustic Multimodal Images.

The rapid development of technologies in biomedical research has enriched and broadened the range of medical equipment. Magnetic resonance imaging, ultrasonic imaging, and optical imaging have been discovered by diverse research communities to design multimodal systems, which is essential for biomedical applications. One of the important tools is photoacoustic multimodal imaging (PAMI) which combines the concepts of optics and ultrasonic systems. At the same time, earlier detection of breast cancer becomes essential to reduce mortality. The recent advancements of deep learning (DL) models enable detection and classification the breast cancer using biomedical images. This article introduces a novel social engineering optimization with deep transfer learning-based breast cancer detection and classification (SEODTL-BDC) model using PAI. The intention of the SEODTL-BDC technique is to detect and categorize the presence of breast cancer using ultrasound images. Primarily, bilateral filtering (BF) is applied as an image preprocessing technique to remove noise. Besides, a lightweight LEDNet model is employed for the segmentation of biomedical images. In addition, residual network (ResNet-18) model can be utilized as a feature extractor. Finally, SEO with recurrent neural network (RNN) model, named SEO-RNN classifier, is applied to allot proper class labels to the biomedical images. The performance validation of the SEODTL-BDC technique is carried out using benchmark dataset and the experimental outcomes pointed out the supremacy of the SEODTL-BDC approach over the existing methods.

Leveraging Tweets for Artificial Intelligence Driven Sentiment Analysis on the COVID-19 Pandemic.

The COVID-19 pandemic has been a disastrous event that has elevated several psychological issues such as depression given abrupt social changes and lack of employment. At the same time, social scientists and psychologists have gained significant interest in understanding the way people express emotions and sentiments at the time of pandemics. During the rise in COVID-19 cases with stricter lockdowns, people expressed their sentiments on social media. This offers a deep understanding of human psychology during catastrophic events. By exploiting user-generated content on social media such as Twitter, people's thoughts and sentiments can be examined, which aids in introducing health intervention policies and awareness campaigns. The recent developments of natural language processing (NLP) and deep learning (DL) models have exposed noteworthy performance in sentiment analysis. With this in mind, this paper presents a new sunflower optimization with deep-learning-driven sentiment analysis and classification (SFODLD-SAC) on COVID-19 tweets. The presented SFODLD-SAC model focuses on the identification of people's sentiments during the COVID-19 pandemic. To accomplish this, the SFODLD-SAC model initially preprocesses the tweets in distinct ways such as stemming, removal of stopwords, usernames, link punctuations, and numerals. In addition, the TF-IDF model is applied for the useful extraction of features from the preprocessed data. Moreover, the cascaded recurrent neural network (CRNN) model is employed to analyze and classify sentiments. Finally, the SFO algorithm is utilized to optimally adjust the hyperparameters involved in the CRNN model. The design of the SFODLD-SAC technique with the inclusion of an SFO algorithm-based hyperparameter optimizer for analyzing people's sentiments on COVID-19 shows the novelty of this study. The simulation analysis of the SFODLD-SAC model is performed using a benchmark dataset from the Kaggle repository. Extensive, comparative results report the promising performance of the SFODLD-SAC model over recent state-of-the-art models with maximum accuracy of 99.65%.

Multiclass Classification of Chest X-Ray Images for the Prediction of COVID-19 Using Capsule Network.

It is critical to establish a reliable method for detecting people infected with COVID-19 since the pandemic has numerous harmful consequences worldwide. If the patient is infected with COVID-19, a chest X-ray can be used to determine this. In this work, an X-ray showing a COVID-19 infection is classified by the capsule neural network model we trained to recognise. 6310 chest X-ray pictures were used to train the models, separated into three categories: normal, pneumonia, and COVID-19. This work is considered an improved deep learning model for the classification of COVID-19 disease through X-ray images. Viewpoint invariance, fewer parameters, and better generalisation are some of the advantages of CapsNet compared with the classic convolutional neural network (CNN) models. The proposed model has achieved an accuracy greater than 95% during the model's training, which is better than the other state-of-the-art algorithms. Furthermore, to aid in detecting COVID-19 in a chest X-ray, the model could provide extra information.

Detection of Dental Diseases through X-Ray Images Using Neural Search Architecture Network.

An important aspect of the diagnosis procedure in daily clinical practice is the analysis of dental radiographs. This is because the dentist must interpret different types of problems related to teeth, including the tooth numbers and related diseases during the diagnostic process. For panoramic radiographs, this paper proposes a convolutional neural network (CNN) that can do multitask classification by classifying the X-ray images into three classes: cavity, filling, and implant. In this paper, convolutional neural networks are taken in the form of a NASNet model consisting of different numbers of max-pooling layers, dropout layers, and activation functions. Initially, the data will be augmented and preprocessed, and then, the construction of a multioutput model will be done. Finally, the model will compile and train the model; the evaluation parameters used for the analysis of the model are loss and the accuracy curves. The model has achieved an accuracy of greater than 96% such that it has outperformed other existing algorithms.

Efficient E-Mail Spam Detection Strategy Using Genetic Decision Tree Processing with NLP Features.

In this modern era, each and everything is computerized, and everyone has their own smart gadgets to communicate with others around the globe without any range limitations. Most of the communication pathways belong to smart applications, call options in smartphones, and other multiple ways, but e-mail communication is considered the main professional communication pathway, which allows business people as well as commercial and noncommercial organizations to communicate with one another or globally share some important official documents and reports. This global pathway attracts many attackers and intruders to do a scam with such innovations; in particular, the intruders generate false messages with some attractive contents and post them as e-mails to global users. This kind of unnecessary and not needed advertisement or threatening mails is considered as spam mails, which usually contain advertisements, promotions of a concern or institution, and so on. These mails are also considered or called junk mails, which will be reflected as the same category. In general, e-mails are the usual way of message delivery for business oriented as well as any official needs, but in some cases there is a necessity of transferring some voice instructions or messages to the destination via the same e-mail pathway. These kinds of voice-oriented e-mail accessing are called voice mails. The voice mail is generally composed to deliver the speech aspect instructions or information to the receiver to do some particular tasks or convey some important messages to the receiver. A voice-mail-enabled system allows users to communicate with one another based on speech input which the sender can communicate to the receiver via voice conversations, which is used to deliver voice information to the recipient. These kinds of mails are usually generated using personal computers or laptops and exchanged via general e-mail pathway, or separate paid and nonpaid mail gateways are available to deal with certain mail transactions. The above-mentioned e-mail spam is considered in many past researches and attains some solutions, but in case of voice-based e-mail aspect, there will be no options to manage such kind of security parameters. In this paper, a hybrid data processing mechanism is handled with respect to both text-enabled and voice-enabled e-mails, which is called Genetic Decision Tree Processing with Natural Language Processing (GDTPNLP). This proposed approach provides a way of identifying the e-mail spam in both textual e-mails and speech-enabled e-mails. The proposed approach of GDTPNLP provides higher spam detection rate in terms of text extraction speed, performance, cost efficiency, and accuracy. These all will be explained in detail with graphical output views in the Results and Discussion.

Ensemble Deep-Learning-Enabled Clinical Decision Support System for Breast Cancer Diagnosis and Classification on Ultrasound Images.

Clinical Decision Support Systems (CDSS) provide an efficient way to diagnose the presence of diseases such as breast cancer using ultrasound images (USIs). Globally, breast cancer is one of the major causes of increased mortality rates among women. Computer-Aided Diagnosis (CAD) models are widely employed in the detection and classification of tumors in USIs. The CAD systems are designed in such a way that they provide recommendations to help radiologists in diagnosing breast tumors and, furthermore, in disease prognosis. The accuracy of the classification process is decided by the quality of images and the radiologist's experience. The design of Deep Learning (DL) models is found to be effective in the classification of breast cancer. In the current study, an Ensemble Deep-Learning-Enabled Clinical Decision Support System for Breast Cancer Diagnosis and Classification (EDLCDS-BCDC) technique was developed using USIs. The proposed EDLCDS-BCDC technique was intended to identify the existence of breast cancer using USIs. In this technique, USIs initially undergo pre-processing through two stages, namely wiener filtering and contrast enhancement. Furthermore, Chaotic Krill Herd Algorithm (CKHA) is applied with Kapur's entropy (KE) for the image segmentation process. In addition, an ensemble of three deep learning models, VGG-16, VGG-19, and SqueezeNet, is used for feature extraction. Finally, Cat Swarm Optimization (CSO) with the Multilayer Perceptron (MLP) model is utilized to classify the images based on whether breast cancer exists or not. A wide range of simulations were carried out on benchmark databases and the extensive results highlight the better outcomes of the proposed EDLCDS-BCDC technique over recent methods.