RESUMO
PURPOSE: To observe the frequency of the occurrence of the anophthalmic socket in the Middle West region of the state of São Paulo and to describe the demographic profile of the carriers in a population-based data. METHODS: A cross-sectional study involve a random sampling carried out in twelve cities of the Middle West region of the state of São Paulo, for which the reference center is the city of Botucatu was done. The participators were chosen by assortment which considered the houses of these people. It was established a sampling with 11,453 people. All the exams were realized using a Mobile Ophthalmologic Unit. The research protocol included the demographic data and the complete ophthalmologic exam (anamnesis, ocular and systemic antecedents, familiar antecedents, visual acuity with and without correction, tonometry, biomicroscopy, fundoscopy, and refraction exam). All the data were transferred to an Excel spreadsheet and submitted to a descriptive analysis and were presented by the frequency of the occurrence. RESULTS: Ophthalmic socket frequency in the Middle West region of the state of São Paulo was 0.96. We found 11 cases of anophthalmic socket, with involvement of 0.7 in females and 1.3 , male. The most common causes of anophthalmic socket were glaucoma (blind painful eye), microphthalmia, trauma, and endophthalmitis. The majority of the people were 40 years old or more, and we found just one person younger than 19 years old. CONCLUSION: The anophthalmic socket occurred in 0.96 of the habitants of the Middle West region of São Paulo State, occurring mainly in male and with large variety of the affected ages.
Assuntos
Anoftalmia/epidemiologia , Adolescente , Adulto , Distribuição por Idade , Idoso , Brasil/epidemiologia , Criança , Estudos Transversais , Monitoramento Epidemiológico , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Vigilância da População , Prevalência , Distribuição por SexoRESUMO
OBJETIVO: Observar a frequência de ocorrência de casos de cavidade anoftálmica na região centro-oeste paulista e descrever o perfil demográfico dos portadores em estudo populacional. MÉTODOS: Estudo transversal, de caráter observacional e de amostragem aleatória, realizado em 12 cidades da região centro-oeste do estado de São Paulo, para as quais o centro de referência é a cidade de Botucatu. Os participantes foram determinados por sorteio que levou em conta o local de moradia, tendo sido estabelecida uma amostra de 11.453 indivíduos. Todos os exames foram feitos utilizando uma Unidade Oftalmológica Móvel. O protocolo da pesquisa consistiu de dados demográficos e exame oftalmológico completo (anamnese, antecedentes oculares e sistêmicos, antecedentes familiares, avaliação da acuidade visual com e sem correção, tonometria, biomicroscopia, fundoscopia e exame refracional). Todos os dados obtidos foram transferidos para tabela Excel e submetidos à análise descritiva e apresentados como frequência de ocorrência. RESULTADOS: A frequência de ocorrência de cavidade anoftálmica na região centro-oeste paulista foi de 0,96‰. Dentre os sujeitos examinados, foram encontrados 11 casos de cavidade anoftálmica, com acometimento de 0,7‰, no sexo feminino e 1,3‰, do sexo masculino. Dentre as causas de cavidade anoftálmica foram encontradas glaucoma (olho cego doloroso), microftalmia, trauma e endoftalmite. Os indivíduos eram, em sua maioria, de idade superior ou igual a 40 anos, tendo sido encontrado apenas um caso com idade abaixo de 19 anos. CONCLUSÃO: A cavidade anoftálmica ocorreu em 0,96‰ dos habitantes da região centro-oeste paulista, acometendo mais frequentemente os homens e com grande variação de idade de acometimento.
PURPOSE: To observe the frequency of the occurrence of the anophthalmic socket in the Middle West region of the state of São Paulo and to describe the demographic profile of the carriers in a population-based data. METHODS: A cross-sectional study involve a random sampling carried out in twelve cities of the Middle West region of the state of São Paulo, for which the reference center is the city of Botucatu was done. The participators were chosen by assortment which considered the houses of these people. It was established a sampling with 11,453 people. All the exams were realized using a Mobile Ophthalmologic Unit. The research protocol included the demographic data and the complete ophthalmologic exam (anamnesis, ocular and systemic antecedents, familiar antecedents, visual acuity with and without correction, tonometry, biomicroscopy, fundoscopy, and refraction exam). All the data were transferred to an Excel spreadsheet and submitted to a descriptive analysis and were presented by the frequency of the occurrence. RESULTS: Ophthalmic socket frequency in the Middle West region of the state of São Paulo was 0.96‰. We found 11 cases of anophthalmic socket, with involvement of 0.7 ‰ in females and 1.3 ‰, male. The most common causes of anophthalmic socket were glaucoma (blind painful eye), microphthalmia, trauma, and endophthalmitis. The majority of the people were 40 years old or more, and we found just one person younger than 19 years old. CONCLUSION:The anophthalmic socket occurred in 0.96‰ of the habitants of the Middle West region of São Paulo State, occurring mainly in male and with large variety of the affected ages.
Assuntos
Adolescente , Adulto , Idoso , Criança , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Anoftalmia/epidemiologia , Distribuição por Idade , Brasil/epidemiologia , Estudos Transversais , Monitoramento Epidemiológico , Vigilância da População , Prevalência , Distribuição por SexoRESUMO
The main goal of our research was to search for SSRs in the Eucalyptus EST FORESTs database (using a software for mining SSR-motifs). With this objective, we created a database for cataloging Eucalyptus EST-derived SSRs, and developed a bioinformatics tool, named Satellyptus, for finding and analyzing microsatellites in the Eucalyptus EST database. The search for microsatellites in the FORESTs database containing 71,115 Eucalyptus EST sequences (52.09 Mb) revealed 20,530 SSRs in 15,621 ESTs. The SSR abundance detected on the Eucalyptus ESTs database (29% or one microsatellite every four sequences) is considered very high for plants. Amongst the categories of SSR motifs, the dimeric (37%) and trimeric ones (33%) predominated. The AG/CT motif was the most frequent (35.15%) followed by the trimeric CCG/CGG (12.81%). From a random sample of 1,217 sequences, 343 microsatellites in 265 SSR-containing sequences were identified. Approximately 48% of these ESTs containing microsatellites were homologous to proteins with known biological function. Most of the microsatellites detected in Eucalyptus ESTs were positioned at either the 5 or 3 end. Our next priority involves the design of flanking primers for codominant SSR loci, which could lead to the development of a set of microsatellite-based markers suitable for marker-assisted Eucalyptus breeding programs