[Influence of Solcotrichovac vaccine on formation of neutrophil extracellular traps].

AIM: To study the influence of Solcotichovac vaccine on formation of neutrophil extracellular traps. MATERIALS AND METHODS: Solcotrichovac vaccine administered in various doses was used in order to assess the formation of neutrophil extracellular traps in peripheral blood of women of childbearing age. RESULTS: Therapeutic dose of Solcotrichovac stimulated the most prominent formation of neutrophil extracellular traps. CONCLUSION: Solcotrichovac vaccine stimulated non-specific arm of mucosal immunity due to formation of neutrophil extracellular traps and it is probable that this mechanism explains the effect of this vaccine.

[The effect of the peptide fractions of neutrophilokines on the immune response of mice infected with Staphylococcus aureus]. / Vliianie peptidnykh fraktsii neitrofilokinov na immunyi otvet myshei, zarazhennykh Staphylococcus aureus.

The influence of immunostimulating and immunosuppressing neutrophilokine fractions on the immune response of mice with staphylococcal infection has been studied. When injected into mice with staphylococcal infection, the immunostimulating fraction of the supernatants of activated neutrophils has been found to restore the activity of the immune system of the infected animals. The secretory products of intact neutrophils do not change or decrease the capacity of the animals for immune response under the conditions of the infectious process.