RESUMO
This is a study on the longitudinal evaluation of cognitive functions in multiple sclerosis (MS) patients and their quality of life (QoL). The study follow-up lasted for 3 years and the evaluation was performed every 9 months for four times altogether. We present data on the first and second session, when we evaluated the frontal component of cognitive functions, behavioural memory and quality of life. We administered the Luria Frontal Lobe Syndrome test (LFLS), the Rivermead Behavioural Memory Test (RBMT), the State-Trait Anxiety Inventory (STAI), the Beck Depression Inventory (BDI), SF-36 for QoL evaluation. The frontal component of cognitive functions and behavioural memory involvement is related to a worsening of QoL, in particular in the Physical Functioning and the Mental Health of SF-36.
Assuntos
Cognição , Esclerose Múltipla/fisiopatologia , Esclerose Múltipla/psicologia , Qualidade de Vida , Adulto , Ansiedade/psicologia , Depressão/psicologia , Emoções , Feminino , Humanos , Estudos Longitudinais , Masculino , Memória , Entrevista Psiquiátrica Padronizada , Pessoa de Meia-Idade , Inquéritos e QuestionáriosRESUMO
F-wave main characteristics were investigated following stimulation of 8 different nerves (facial, axillary, radial, median, ulnar, femoral, deep peroneal, posterior tibial) in a population of normal healthy subjects. Additional studies compared different stimulation and recording techniques (stimulus intensity, stimulus duration, number of consecutive stimuli, facilitating maneuvers, type of recording electrodes). F-wave persistency varied markedly among the different nerves. Mean latencies were correlated to subjects' height, whereas conduction velocity was related to age. The optimal stimulation and recording parameters to obtain reliable information on F-wave studies were: stimulation duration of 0.2 msec with a strength adjusted 30% supramaximal to the direct M-response; administration of a train composed of 10 consecutive stimuli at rest and recording by concentric needle electrodes.
Assuntos
Nervos Periféricos/fisiologia , Adulto , Idoso , Análise de Variância , Eletromiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Músculos/fisiologia , Tempo de Reação/fisiologia , Valores de ReferênciaRESUMO
Sympathetic skin responses (SSRs) were abolished in 4 patients affected with fatal familial thalamic degeneration involving the anterior (A) and dorsomedial (DM) thalamic nuclei, without lesions of the peripheral vegetative system. Abnormalities of SSR were not due to peripheral nerve lesions. It is concluded that SSR integrity also depends upon thalamic formations ("visceral" thalamus) and their frontal cortical connections.
