1.
J Clin Pharm Ther
; 43(5): 717-722, 2018 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29722042
RESUMO
WHAT IS KNOWN AND OBJECTIVE: Toxic prolongation of the QRS interval most often results from blockade of cardiac voltage-gated sodium channels and manifests on electrocardiogram with a right bundle-branch block-like morphology. Rarely, a left bundle-branch block (LBBB) morphology has been reported. CASE REPORT: We report a case of transient LBBB resultant from ingestion of lamotrigine and citalopram which was refractory to sodium bicarbonate therapy and eventually resolved spontaneously. WHAT IS NEW AND CONCLUSION: Cases of toxic LBBB are less likely to respond to bicarbonate therapy, suggesting that this finding is due to a mechanism other than sodium channel blockade.
Assuntos
Arritmias Cardíacas/induzido quimicamente , Bicarbonatos/efeitos adversos , Bloqueio de Ramo/induzido quimicamente , Citalopram/efeitos adversos , Eletrocardiografia/efeitos dos fármacos , Lamotrigina/efeitos adversos , Adulto , Feminino , Humanos
2.
RN
; 40(9): 43-7, 1977 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-587424