RESUMO
Human infections by Pasteurella multocida are usually associated with bites or scratches from dogs and cats. Many of them are accompanied by other oropharyngeal microorganisms of these animals. We herein present a case of bacteremic meningitis by P. multocida in an 86-year-old woman who was living with seven cats. Even though no skin or soft tissue infection was recorded, it is possible that a mild infection had gone undetected and a subsequent bacteremia had impacted on the meninges, or that meningitis could have occurred after nasopharyngeal colonization (not demonstrated). The isolates obtained from blood cultures and cerebrospinal fluid were identified as P. multocida by API 20NE, API 20E, and Vitek 1. In agreement with findings in the literature, this strain was susceptible to penicillin, cefotaxime, levofloxacin and tetracyclines.
Assuntos
Bacteriemia/microbiologia , Meningites Bacterianas/microbiologia , Infecções por Pasteurella/microbiologia , Pasteurella multocida/isolamento & purificação , Idoso de 80 Anos ou mais , Ampicilina/uso terapêutico , Animais , Antibacterianos/uso terapêutico , Doenças do Gato/microbiologia , Gatos/microbiologia , Ceftriaxona/uso terapêutico , Dexametasona/uso terapêutico , Quimioterapia Combinada , Feminino , Humanos , Infecções por Pasteurella/transmissão , Infecções por Pasteurella/veterinária , Pasteurella multocida/efeitos dos fármacosRESUMO
Brucella canis and other species of the genus Brucella can cause human disease. However, this species infrequently cause human disease, including in countries where dogs population is highly infected. A 15 years old male was admitted to the hospital with 15 days history of fever without visible focus. Physical examination revealed pain at liver palpation and axillar, cervical and inguinal lymphoadenomegalies. Abdominal ultrasonography showed spleenomegally, the chest Rx and the trans thoracic echocardiogram were normal. Five blood samples were obtained and cultured in 2 standards bottles (time of positivization 72 - 64.8 hours), and 3 pediatric FAN bottles (time of positivization 74.5; 72 and 67.2 hours) (Bact-Alert system, Biomerieux, Marcy, l'Etolie, France). The microorganism was presuntive identified as B. canis, and then was confirmed in the National Reference Center Instituto ANLIS "Carlos G. Malbran". After 14 days of initiating ceftriaxone treatment the patient was afebrile. When the confirmation of Brucella was made, he was discharged and ambulatory was prescribed with doxycycline and rifampin for 21 days. Bones were not compromised and the outcome was good with complete resolution of his illness.
Assuntos
Bacteriemia/microbiologia , Brucella canis/isolamento & purificação , Brucelose/diagnóstico , Adolescente , Bacteriemia/diagnóstico , Técnicas Bacteriológicas , Humanos , MasculinoRESUMO
Brucella canis and other species of the genus Brucella can cause human disease. However, this species infrequently cause human disease, including in countries where dogs population is highly infected. A 15 years old male was admitted to the hospital with 15 days history of fever without visible focus. Physical examination revealed pain at liver palpation and axillar, cervical and inguinal lymphoadenomegalies. Abdominal ultrasonography showed spleenomegally, the chest Rx and the trans thoracic echocardiogram were normal. Five blood samples were obtained and cultured in 2 standards bottles (time of positivization 72 - 64.8 hours), and 3 pediatric FAN bottles (time of positivization 74.5; 72 and 67.2 hours) (Bact-Alert system, Biomerieux, Marcy, lEtolie, France). The microorganism was presuntive identified as B. canis, and then was confirmed in the National Reference Center Instituto ANLIS [quot ]Carlos G. Malbran[quot ]. After 14 days of initiating ceftriaxone treatment the patient was afebrile. When the confirmation of Brucella was made, he was discharged and ambulatory was prescribed with doxycycline and rifampin for 21 days. Bones were not compromised and the outcome was good with complete resolution of his illness.
RESUMO
Brucella canis and other species of the genus Brucella can cause human disease. However, this species infrequently cause human disease, including in countries where dogs population is highly infected. A 15 years old male was admitted to the hospital with 15 days history of fever without visible focus. Physical examination revealed pain at liver palpation and axillar, cervical and inguinal lymphoadenomegalies. Abdominal ultrasonography showed spleenomegally, the chest Rx and the trans thoracic echocardiogram were normal. Five blood samples were obtained and cultured in 2 standards bottles (time of positivization 72 - 64.8 hours), and 3 pediatric FAN bottles (time of positivization 74.5; 72 and 67.2 hours) (Bact-Alert system, Biomerieux, Marcy, lEtolie, France). The microorganism was presuntive identified as B. canis, and then was confirmed in the National Reference Center Instituto ANLIS [quot ]Carlos G. Malbran[quot ]. After 14 days of initiating ceftriaxone treatment the patient was afebrile. When the confirmation of Brucella was made, he was discharged and ambulatory was prescribed with doxycycline and rifampin for 21 days. Bones were not compromised and the outcome was good with complete resolution of his illness.