Septal Lipoma and Cleft Palate: Particular Association, Particular Treatment?

Congenital tumors of the oral cavity are infrequent and is dominated by teratogenic tumors. They are rarely associated with cleft palate. Congenital lipoma of the palate in patients with cleft palate remains exceptional. We report a case of congenital septal lipoma with cleft palate (the third case of such association is reported in the literature) and discuss the surgical treatment in light of the evolution of the patient.

A recurrent mutation in Moroccan patients with Dyggve-Melchior-Clausen syndrome: Report of a new case and review.

Dyggve-Melchior-Clausen (DMC) syndrome is a rare autosomal recessive disorder. It is a spondyloepimetaphyseal dysplasia associated with mental retardation. Clinical manifestations include coarse facies, microcephaly, short trunk dwarfism, and mental retardation. Mutations in Dymeclin gene (DYM), mapped to chromosome 18q21.1, is responsible for DMC. We report here the observation of a consanguineous Moroccan patient having DMC syndrome. The molecular studies showed a previously reported homozygous mutation at c.1878delA of DYM gene. We discuss this recurrent mutation in Moroccan patients with DMC syndrome with a review.