RESUMO
The paper is concerned with the clinical testing of irradiation fractionation in photon therapy, of which the optimum variant was worked out using a method of mathematical simulation. It was conducted in 30 patients with osteogenic sarcoma. In 5 cases a course of photon therapy was supplemented by neutron irradiation. Good tolerance of the proposed scheme by the patients, the absence of contraindications for its administration and marked antitumor efficacy were revealed. Radiation pathomorphism of osteogenic sarcoma after photon and neutron therapy was described.
Assuntos
Neoplasias Ósseas/radioterapia , Nêutrons/uso terapêutico , Osteossarcoma/radioterapia , Adolescente , Adulto , Neoplasias Ósseas/patologia , Criança , Pré-Escolar , Estudos de Avaliação como Assunto , Feminino , Humanos , Masculino , Osteossarcoma/patologia , Tolerância a Radiação , Dosagem RadioterapêuticaRESUMO
A working classification of vertebral tumors is discussed. The classification is based on tumor process expansion, presence of soft-tissue component and the degree of vertebral and neurologic complications. The extent and type of surgical procedure are determined in accordance with the authors' approach to tumor process staging.