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Emerg Infect Dis ; 17(9): 1615-23, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21888786

RESUMO

Pandemic (H1N1) 2009 influenza spread through the Northern Territory, Australia, during June-August 2009. We performed 2 cross-sectional serologic surveys on specimens from Northern Territory residents, with 445 specimens obtained prepandemic and 1,689 specimens postpandemic. Antibody titers were determined by hemagglutination inhibition against reference virus A/California/7/2009 on serum samples collected opportunistically from outpatients. All specimens had data for patients' gender, age, and address, with patients' indigenous status determined for 94.1%. Protective immunity (titer >40) was present in 7.6% (95% confidence interval [CI] 5.2%-10.1%) of prepandemic specimens and 19.5% (95% CI 17.6%-21.4%) of postpandemic specimens, giving a population-standardized attack rate of 14.9% (95% CI 11.0%-18.9%). Prepandemic proportion of immune persons was greater with increasing age but did not differ by other demographic characteristics. Postpandemic proportion of immune persons was greater in younger groups and around double in indigenous persons. Postpandemic proportion immune was geographically heterogeneous, particularly among remote-living and indigenous groups.


Assuntos
Vírus da Influenza A Subtipo H1N1/imunologia , Influenza Humana/etnologia , Pandemias , Imunidade Adaptativa , Adolescente , Adulto , Anticorpos Antivirais/sangue , Criança , Estudos Transversais , Humanos , Incidência , Influenza Humana/imunologia , Influenza Humana/virologia , Pessoa de Meia-Idade , Havaiano Nativo ou Outro Ilhéu do Pacífico , Northern Territory/epidemiologia , Análise de Regressão , População Rural , Adulto Jovem
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