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1.
J Cardiovasc Surg (Torino) ; 52(5): 739-48, 2011 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-21894141

RESUMO

AIM: Recent reports have suggested harvesting of the greater saphenous vein for coronary artery bypass (CABG) using endoscopic techniques (endoscopic) results in early graft closure, higher rates of myocardial infarction (MI) and death. We explored the impact of this technique performed by experienced operators on postoperative morbidities, MI and death in our CABG patients. METHODS: All non-emergent patients presenting for first time CABG surgery from 2006 to June 2009 were included. Data pertaining to surgery, readmissions, cardiac catheterization and interventions during long term follow-up were extracted from our local STS and ACC registries. Linear and logistic regressions with clinical covariates were conducted to determine if vein harvest technique group predicted the major outcomes. Propensity score matching (PSM) was completed to simulate randomization and improve covariate balance across the endoscopic and direct vision groups. RESULTS: One thousand nine hundred and eighty-eight (N.=1988) patients were evaluated in this study (N.=1734 endoscopic group and N.=254 direct vision group). The perioperative major adverse outcomes (mortality within 30 days, stroke, reoperation for bleeding, prolonged ventilation and readmission within 30 days) were 17.8% in the endoscopic group and 25.2% in the direct vision group. The rate of leg infections was 0.3% for the endoscopic group and 1.6% for the direct vision group. After adjustment for covariates, the direct vision group had significantly greater risk for prolonged ventilation (P=0.03), MACE (P=0.02) and mortality within 30 days (P=0.01), but only marginally greater risk for leg infections (P=0.052). In the isolated CABG patients, operative death was 1% for the endoscopic group and 1.7% in the direct vision group (P=0.62). After PSM the endoscopic group was similar on all outcomes except for having fewer MACE (P=0.04). In a mean follow-up of 22.1±10.5 months, there were no significant differences in the overall rate and time to event for repeat revascularization, death and myocardial infarction. With maximum follow up of 39.6 months, 84 deaths were documented (N.=67 endoscopic and N.=17 direct vision). CONCLUSION: The outcomes captured by the number of postoperative morbidities, incidence of myocardial infarction and/or the rate of death for the endoscopic technique were comparable to patients in whom the open techniques was used. There was a trend towards a decrease in leg infections with the use of the endoscopic device. Based on this study we consider the device safe and effective with experienced operators.


Assuntos
Ponte de Artéria Coronária , Endoscopia , Veia Safena/transplante , Coleta de Tecidos e Órgãos/métodos , Idoso , Distribuição de Qui-Quadrado , Ponte de Artéria Coronária/efeitos adversos , Ponte de Artéria Coronária/mortalidade , Endoscopia/efeitos adversos , Endoscopia/mortalidade , Feminino , Humanos , Estimativa de Kaplan-Meier , Modelos Lineares , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Infarto do Miocárdio/etiologia , Readmissão do Paciente , Hemorragia Pós-Operatória/etiologia , Pontuação de Propensão , Modelos de Riscos Proporcionais , Sistema de Registros , Reoperação , Respiração Artificial , Estudos Retrospectivos , Medição de Risco , Fatores de Risco , Acidente Vascular Cerebral/etiologia , Infecção da Ferida Cirúrgica/etiologia , Fatores de Tempo , Coleta de Tecidos e Órgãos/efeitos adversos , Coleta de Tecidos e Órgãos/mortalidade , Resultado do Tratamento , Virginia
4.
Ann Thorac Surg ; 55(6): 1425-30; discussion 1430-1, 1993 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-8512391

RESUMO

The Thermo Cardiosystems (TCI) HeartMate, a pneumatically driven, implantable left ventricular assist device, was designed for long-term support of the failing heart. Between February 1990 and August 1992, the HeartMate was implanted in 11 heart transplant candidates because of profound deterioration of left ventricular function. Patients had a mean cardiac index of 1.6 L.min-1 x m-2 and a mean pulmonary capillary wedge pressure of 33 mm Hg despite maximal pharmacologic support with at least three inotropic medications. In addition, 5 patients were being supported with an intraaortic balloon pump. Nine patients were bridged successfully to cardiac transplantation. The mean cardiac index after implantation of the left ventricular assist device was 3.2 L.min-1 x m-2. Support ranged from 2 to 143 days (mean duration, 60 days). One patient died early of low output secondary to right heart failure, and a second died of air embolism, which occurred intraoperatively. All surviving patients became fully ambulatory. There were no thromboembolic complications during a total of 658 patient-days of support on a regimen of only 80 mg of aspirin daily. The 9 bridged patients are currently alive 4 to 34 months after transplantation. The TCI HeartMate provides safe and effective hemodynamic support with low risk of complications and virtual freedom from thromboembolism on a regimen of minimal anticoagulation.


Assuntos
Transplante de Coração , Coração Auxiliar , Adulto , Aspirina/uso terapêutico , Débito Cardíaco/fisiologia , Desenho de Equipamento , Feminino , Coração Auxiliar/efeitos adversos , Humanos , Balão Intra-Aórtico , Masculino , Pressão Propulsora Pulmonar/fisiologia , Infecção da Ferida Cirúrgica/epidemiologia , Tromboembolia/epidemiologia , Fatores de Tempo , Função Ventricular Esquerda/fisiologia
5.
Ann Thorac Surg ; 45(5): 559-60, 1988 May.
Artigo em Inglês | MEDLINE | ID: mdl-3284492

RESUMO

Transaxillary thoracotomy is a well-known but underused approach to both benign and malignant conditions in the chest. The traditional posterolateral thoracotomy affords little advantage over this incision in terms of staging of disease or therapeutic resection. Previous reports have emphasized the wide range of conditions for which this approach is suitable, but advances in the technique and design of stapling devices and routine use of the double-lumen endotracheal tube have further enhanced its indications. We have reviewed 54 consecutive patients who have undergone transaxillary thoracotomy over a 2 1/2-year period. The wide range of procedures performed up to and including pneumonectomy indicates the versatility of the approach. We now consider transaxillary thoracotomy to be the incision of choice for most pulmonary and mediastinal lesions and an attractive alternative to mediastinoscopy for the identification and staging of chest tumors.


Assuntos
Toracotomia/métodos , Axila , Biópsia , Humanos , Neoplasias Pulmonares/patologia , Neoplasias Pulmonares/cirurgia , Neoplasias do Mediastino/patologia , Neoplasias do Mediastino/cirurgia
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